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Sunday, March 1, 2015
Saturday, February 28, 2015
Friday, February 27, 2015
The stem cell research division of the Tisch MS Research Center of New York is pleased to announce the completed enrollment of 20 patients to participate in the phase I clinical trial investigating the safety and efficacy of autologous, mesenchymal stem cell-derived neural progenitors (MSC-NPs) for the treatment of multiple sclerosis. We are no longer recruiting for this study. Interim results of this clinical trial will be presented at upcoming scientific conferences and simultaneously announced on our website. All questions regarding participation in any future clinical trials should be discussed with your neurologist.
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Dave's ActiveMS'ers Blog
Thursday, February 26, 2015
Saturday, February 21, 2015
Stem cells were more effective in suppressing the immune system than mitoxantrone, according to research published in Neurology.
Researchers from the University of Genoa in Italy examined 21 patients who received bone barrow to determine if their immune system would be suppressed at the same rate as patients who received mitoxantrone. A dozen patients received mitoxantrone, while 9 patients had stem cells harvested from their bone marrow. The stem cells were reintroduced to the patient’s bodies intravenously. Then, the stem cells traveled to the bone marrow and produced new cells which grew to become immune cells.
After a follow up period of 4 years, patients who received stem cells had 80 percent fewer new brain damage areas than those patients who received mitoxantrone. The stem cell group had an average 2.5 new brain lesions in comparison to 8 new lesions in the mitoxantrone receiving group.
About half (56 percent) of the mitoxantrone treated patients were discovered to have at least one new gadolinium enhancing lesion, which is another type of lesion. The stem cell treatment group had no new gadolinium enhancing lesions found.
“This process appears to reset the immune system,” study author Giovanni Mancardi, MD explained in a press release. “With these results, we can speculate that stem cell treatment may profoundly affect the course of the disease.”
The progression of disability was not different between the 2 groups. The researchers noted the serious side effects that occurred within the stem cell treatment group were anticipated and resolved without further permanent consequences.
Friday, February 20, 2015
PUBLIC RELEASE: 19-FEB-2015
WASHINGTON, DC - Women with multiple sclerosis (MS) may have lower levels of important antioxidant and anti-inflammatory nutrients, such as folate from food and vitamin E, than healthy people, according to a new study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015.
For the study, researchers identified 27 Caucasian women with MS and compared them to 30 healthy Caucasian women between the ages of 18-60 and with body mass index of less than or equal to 30 kg/m2. Participants reported on their diet and nutrition over the previous year prior to starting vitamin D supplementation.
On average, the women who had MS had lower levels of five nutrients with antioxidant or anti-inflammatory properties: food folate, vitamin E, magnesium, lutein-zeaxanthin and quercetin. For food folate, the women with MS had average intake of 244 micrograms (mcg), while the healthy women had an average intake of 321 mcg. The recommended daily allowance is 400 mcg. For magnesium, the women with MS had average intake of 254 milligrams (mg), while the healthy women met the recommended daily allowance of 320 mg with an average of 321 mg. The women with MS also had a lower average percentage of their calories from fat than the healthy participants.
"Since MS is a chronic inflammatory disorder, having enough nutrients with anti-inflammatory properties may help prevent the disease or reduce the risk of attacks for those who already have MS," said study author Sandra D. Cassard, ScD, with John Hopkins University in Baltimore, MD. "Antioxidants are also critical to good health and help reduce the effects of other types of damage that can occur on a cellular level and contribute to neurologic diseases like MS. Whether the nutritional differences that we identified in the study are a cause of MS or a result of having it is not yet clear."
Three young artists convey their experiences of multiple sclerosis in the hope of helping others with their diagnoses.
To find something good out of something bad was the brief given to three young people. They all have multiple sclerosis (MS) and have been creating artistic works that examine how it has affected them in positive ways.
The final pieces - a combination of portraits, photographs and jewelery - are part of a project being run by multiple sclerosis charity Shift MS.
They show, they say, that "no two people have the same experience of MS".
Photographer Hannah Laycock is 32 and works in London. She was diagnosed with MS in 2013 after showing symptoms since February of the same year. Her initial fear was that she had motor neurone disease, which her father has had since 2009. Instead it was confirmed that she had MS.