ms.about.com
Thursday January 15, 2009
There is potential good news coming for users of Avonex, Betaseron and Rebif. Those interferon treatments need to be injected and, let's just go ahead and say it, nobody likes injections.
Nerveda and Aegis Therapeutics announced that they have had successful preclinical results on a nasal spray to deliver the interferons.
The reason you simply can't have an pill for interferon treatment in multiple sclerosis is that this line of treatment relies on delicate protein molecules. Basically, protein molecules like to cling and bond to each other. If they do that too much, the immune system doens't react to them and produce the antibodies needed to reduce relaspe rates. A pill would be too unstable and too "bonded together" for it to be an effective interferon treatment.
A nasal spray would be a big deal. It's an effective (and much less painful) way to deliver interferon treatment. Expect to see clinical trails starting soon..
Leaving Comments, Suggestions and/or Questions, are Always Appreciated. - Thank you
============================================
2 comments:
What will they think of next? This sounds promising...
Lest anyone get too excited too early about this, "preclinical" means that there is an average of 4-7 years before it can come to market. This is not something you or I can do to alleviate site reactions at this point in time or in the foreseeable future.
I love the concept and hope it can be made real but we will not see it available outside of clinical trials for a long time.
If you want to participate in a trial, go to www.clinicaltrials.gov type in Multiple sclerosis then you can see which trials are enrolling for which drugs. It will also tell you the criteria for enrollment when you click onto individual trials.
Post a Comment