Article information provided by Cherie C. Binns RN, BS., MSCN
http://www.medscape.com/viewarticle/586261
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Immunomodulation and Postpartum Relapses in Patients With Multiple Sclerosis
Kerstin Hellwig, MD; Christian Beste; Sebastian Schimrigk; Andrew Chan
Ther Adv Neurol Disorders. 2009;2(1):7-11. ©2009 Sage Publications, Inc.
Posted 02/04/2009
Abstract and Introduction
Abstract
Multiple sclerosis (MS) mainly affects young women during a life period with desire for children. Relapse rate decreases during pregnancy and rises after delivery. Therefore, studies on satisfactory postpartum relapse prevention and its efficacy are essential. Previous smaller and uncontrolled studies suggested that intravenous immunoglobulin (IVIG) administration reduced the relapse rate following delivery. The objective of our observational study was to compare the efficacy of IVIG application, treatment with other immunomodulatory compounds or no treatment at all on the postpartal relapse rate in female MS patients from our pregnancy database.
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