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Monday, May 4, 2009

Natalizumab May Activate Oral Herpes Viruses

By Andrew N. Wilner, MD

SEATTLE, Wash -- May 3, 2009 -- Oral herpes virus (HSV-1) eruptions were 3 times more likely in patients with multiple sclerosis who were taking natalizumab than in multiple sclerosis patients on no therapy, according to research presented here at the American Academy of Neurology (AAN) 61st Annual Meeting.

Nicoline Schiess, MD, Johns Hopkins Medical Center, Baltimore, Maryland, and colleagues evaluated the activity of various herpes viruses in 34 patients with multiple sclerosis taking natalizumab and 34 age- and gender-matched healthy controls, as well as 20 patients with multiple sclerosis on no therapy and 20 patients with multiple sclerosis on interferon therapy. The results of their evaluation were presented here on April 28.

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