An oral drug designed to treat uncontrollable laughing and/or crying (also called pseudobulbar affect), a troubling symptom experienced by some people with MS, ALS, and other neurological disorders, has passed another hurdle by showing positive results in a Phase III trial. According to company sources, Zenvia™ (Avanir Pharmaceuticals) significantly reduced the rate of laughing and crying episodes and appeared to be safe and well tolerated. The company is conducting a complete analysis of the results to present at scientific meetings and to prepare a filing with the U.S. Food and Drug Administration requesting approval to market the drug.
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