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Wednesday, October 7, 2009

Glatiramer Acetate Treatment Reduces Risk of Early MS Progressing to Clinically Definite Disease

Treatment with glatiramer acetate can reduce by almost half the risk of patients progressing from the very early signs of multiple sclerosis (MS) to clinically definite disease, according to a study published early online and in an upcoming edition of The Lancet.

Giancarlo Comi, MD, Department of Neurology, University Vita-Salute, Milan, Italy, and colleagues conducted a randomised, double-blind trial at 80 sites in 16 countries.

A total of 481 patients presenting with a clinically isolated syndrome were randomly assigned to receive either subcutaneous glatiramer acetate 20 mg per day (n = 243) or placebo (n = 238) for up to 36 months, unless they converted to clinically definite MS.

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