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Thursday, June 3, 2010

'Hard To Treat Diseases (HTDS.PK) Scientists' report results that are encouraging for the future of Multiple Sclerosis Treatment


BELGRADE, Serbia, June 3 /PRNewswire-FirstCall/ - Hard to Treat Diseases, Inc. 
(HTDS:PK),http://www.htdsmedical.com announced today that researchers from its Slavica BioChem (www.slavicabiochem.com) division in Belgrade made a great progress in the experimental findings to aid in the suppression or ultimately cure of Multiple Sclerosis which are comparable with investigations of other MS-Research groups around the world.

In a recent press release posted on May 24, 2010 Abbott, and Biogen Idec. announced enrollment of the first patient in a global Phase III study evaluating the efficacy and safety of daclizumab compared to interferon beta-1a (AVONEX(R)) in patients with relapsing-remitting multiple sclerosis (RRMS), the most common form of multiple sclerosis (MS), one of the most common neurological disorders that affects more than 2.5 million people worldwide.

This study is based on investigations of researchers from University Hospital, Basel, Switzerland. Dr Ludwig Kappos, M.D., Head, MS-Research Group, and lead investigator for the study said: "As shown in previous studies, daclizumab appears to selectively target immune cells that are thought to become activated in MS and cause damage to the central nervous system. Daclizumab is a humanized monoclonal antibody that binds to CD25, a receptor subunit that is expressed at low levels on resting T-cells and at high levels on T-cells that are thought to become activated in response to MS. Daclizumab is believed to work by selectively targeting these activated T-cells without causing general T-cell depletion leading to reduction in the number of new or enlarged MS lesions."


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