** Stu's Views & M.S. News **: Cladribine and Natalizumab can adversely interact

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Sunday, August 22, 2010

Cladribine and Natalizumab can adversely interact

August 21, 2010
written by: Cherie C. Binns RN BS MSCN

As I am researching interaction potential between Cladribine (may be approved within the next 3-6 months for treatment of multiple sclerosis) and medications that may adversely interact, natalizamab or Tysabri comes up.

According to this link: http://www.drugs.com/drug-interactions/cladribine-with-natalizumab-684-0-1693-0.html administration of Cladribine to someone who has taken Tysabri has the potential to increase the risk of PML. It does not say if there is a washout period of Tysabri prior to initiation of Cladribine.

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