By David S. MacDougall
GOTHENBURG, Sweden -- October 17, 2010 -- Clinical outcomes in patients with multiple sclerosis (MS) are adversely affected by increased blood levels of low-density lipoprotein (LDL), total cholesterol, and triglycerides, researchers said here on October 14 at the 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS).
Dyslipidaemia independently predicts an increased risk for cardiovascular complications via mechanisms related to activation of inflammatory processes at the vascular endothelial level, said lead study author Bianca Weinstock-Guttman, MD, Jacobs Neurological Institute, Buffalo, New York.
The risk of disease progression in patients with MS has recently been linked to vascular comorbidities, she noted, but the mechanisms underlying this association remain uncertain.
"Cholesterol is an important component of intact myelin," Dr. Weinstock-Guttman said. "Lipids, especially lipoproteins, are involved in the regulation of several neural functions through local independent mechanisms that are linked to systemic lipid metabolism in the CNS [central nervous system]."
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***********************************************************GOTHENBURG, Sweden -- October 17, 2010 -- Clinical outcomes in patients with multiple sclerosis (MS) are adversely affected by increased blood levels of low-density lipoprotein (LDL), total cholesterol, and triglycerides, researchers said here on October 14 at the 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS).
Dyslipidaemia independently predicts an increased risk for cardiovascular complications via mechanisms related to activation of inflammatory processes at the vascular endothelial level, said lead study author Bianca Weinstock-Guttman, MD, Jacobs Neurological Institute, Buffalo, New York.
The risk of disease progression in patients with MS has recently been linked to vascular comorbidities, she noted, but the mechanisms underlying this association remain uncertain.
"Cholesterol is an important component of intact myelin," Dr. Weinstock-Guttman said. "Lipids, especially lipoproteins, are involved in the regulation of several neural functions through local independent mechanisms that are linked to systemic lipid metabolism in the CNS [central nervous system]."
READ MORE
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1 comments:
But before and after my blood levels of choleterol was quite normal!
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