Please visit our MS learning channel on Youtube, which provides hundreds of topics from our education programs, that were video-recorded and archived here: www.youtube.com/msviewsandnews -- Be empowered with MS news by registering with us: www.register.msviewsandnews.org

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Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

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Saturday, August 21, 2010

New "T-Cell" Research May Impact Treatment of MS

August 20, 2010

The internationally-renowned scientific journal Immunity, from the Cell Press group, publishes online today, and will publish in its August 27 print issue, the results of a study conducted by a team of researchers led by Dr. AndrĂ© Veillette, Director of the Molecular Oncology research unit at the Institut de recherches cliniques de MontrĂ©al (IRCM). Their scientific breakthrough could have an impact on the treatment of multiple sclerosis and other autoimmune diseases, which affect tens of thousands of Canadians.

Dr. Veillette's team discovered the function of a protein located in T cells, which are immune cells known as lymphocytes that play a central role in the protection against viruses and other microbial agents. They also take part in the development of certain diseases, including diabetes and multiple sclerosis. The protein in question is the "phosphatase" PTP-PEST, an enzyme that removes phosphates from other proteins in the cell.

"By removing PTP-PEST from mouse T cells, we determined that this protein was required for repeated immune responses such as those occurring during vaccination," explains Dr. Dominique Davidson, a researcher in Dr. Veillette's laboratory and first author of the study. "More particularly, we showed that PTP-PEST controls the activity of Pyk2, a molecule that stimulates the ability of cells to interact with one another and move within the body."

The researchers showed that, through this mechanism, PTP-PEST stimulates the participation of T cells in an immune reaction. Once activated, T cells encourage other immune cells to join in an immune response, thereby explaining their pivotal role in this process. The team's results also show that the elimination of PTP-PEST in T cells can prevent certain autoimmune diseases, at least in mice. This suggests that suppressing the function of PTP-PEST through medication could be of value for the treatment of some human diseases.

"The removal of PTP-PEST can unfortunately prevent immunization and weaken the response to a vaccine," concludes Dr. Veillette. "Fortunately, it can also prevent overactive immune responses and could eventually help treat autoimmune diseases. It's like a double-edged sword."



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Nova Scotia supports debated MS trials

By Bradley Bouzane, Postmedia News August 20, 2010

Nova Scotia is the latest province to throw its weight behind a proposed clinical trial in Canada to administer a controversial treatment to multiple sclerosis patients.

N.S. Premier Darrell Dexter said Friday that it was joining other provinces in supporting a national randomized clinical trial of the so-called liberation treatment.

"We've said we think there needs to be leadership from the federal government on the question of national trials, and that we would participate in those trials," Dexter said, adding the trials would have to meet guidelines and include patients from across the country.

"Of course, we want to ensure we're proceeding in an appropriate and cautious manner because this is a controversial therapy, but also one that offers hope to people who are suffering from MS. If it shows promise and there's the possibility there will be benefit, we'll do our part to pursue it."

Read more


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Friday, August 20, 2010

MS Views and News Inc., is seeking volunteers for various roles...

Volunteer efforts that are needed for 'MS Views and News Inc' ( MSV&N) are found below.
 
1) Grant writing -- we need Federal and State Grants to help grow this company.
 
2) Following up with previously submitted sponsorship requests to corporations.
 
3) Obtaining listings of Corporations / Philanthropists that give to "Not for Profits" that provide education and educational seminars.
 
4) Applying for Sponsorships with Corporations and to Philanthropists that give to "Not for Profits" that provide educational information.
 
5) Following up with the applied-for sponsorships.
 
6) Putting together fundraisers (from beginning to finish).
 
7) Providing our Organization Flyer to MS Centers and Neurology offices in Miami-Dade, Broward and Monroe Counties.
 
8) Social Media -- Someone to be involved daily with facebook and/or twitter - providing our information and educating person affected by MS with and of MSV&N.
 
If you or anybody you know can volunteer to help us with any of the above efforts, please let us  know by writing to: info@msviewsandnews.org.
 

Thanking you in advance.
 
Appreciatively, 
 
Stuart Schlossman
President & Founder of MS Views and News, Inc.
Editor of Stu's Views and MS Related News

 
 
'MS Views and News' is unique in what we do. Bridging the gap to all major MS Organizations. Providing information and resources from our website, daily via our blog and weekly by our e-newsletter (Stu's Views and MS Related News). 

Thursday, August 19, 2010

CCSVI and Multiple Sclerosis (MS)

The National MS Society
and MS Learn Online present...

A new Feature Presentation:
 
 
A video webcast that explores...
 
  • What is CCSVI?
  • Should I be tested and treated for CCSVI?
  • What is being done to learn more?
 
Click here to view the webcast, or copy into your browser: http://www.nationalmssociety.org/multimedia-library/ms-learn-online/index.aspx


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'Shop for a Cause', will benefit an MS Not for Profit


Dear MS Friends,                                                     Aug 2010

This offer is for You, Your family and Your friends. Please forward this email to others in your address book. You will be saving at Macy's and helping MSV&N to raise money.

SHOP for a CAUSE - Find THE MAGIC of Giving Back on Saturday October 16th, 2010.
It's Fast and Simple. Purchase a $5.00  Macy's Coupon from 'MS Views and News' and get up to a 20% discount from Macy's on October 16th.  The coupon will also allow you to ENTER FOR A CHANCE TO WIN A $500.00 Gift Card.

MS Views and News has partnered with Macy’s nationwide (USA) in a Shop for a Cause event. Macy’s has been sponsoring this event since 2006. 

For only a $5.00 donation to MSV&N you will receive one ticket to be used at any Macy’s department store, anywhere at all.  This coupon entitles you to shop at Macy’s on Saturday, October 16, 2010. Shop for a Cause tickets provide discount savings in most departments all day long. Shop for a Cause is special because you can save on most items throughout the store and online. Additionally you will be entered for an opportunity to win a $500 gift card. Your charitable donation to 'MS Views and News' (MSV&N) is tax deductible.







Kindly submit your $5.00 donation plus an additional $0.50 to cover postage and handling, for a total of $5.50, and you will be sent your saving coupon by mail.  All Macy’s tickets will be sent upon receipt of your contribution. 


Please mail your check or cash donation to: 
MS Views and News, Inc.
8669 SW 51st Street
Cooper City, Fl. 33328-4301

Credit card donations, including Master Card and Visa, will be accepted by email (see below) or telephone to Stuart Schlossman at 954-684-1683. Please be sure to provide a mailing address for any coupon which requires mailing. 


Feel free to contact (jebmol@aol.com) or the founder and president of MS Views and News, Stuart Schlossman (stuart@msviewsandnews.org) with any questions.

Please respond quickly so that you receive your ticket in a timely fashion.
Tickets are limited so act fast and act now.
We extend our profoundest gratitude to you for helping us and for supporting the MS community.


Most Sincerely,

Jill Molberger
Campaign Leader


"MS Views and News" (MSV&N) is a 501©(3) organization as recognized by the Internal Revenue Service

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Podcast #4 - MS Pain and Symptoms



CLICK: 

You Tube Video of Podcast #4 on MS Pain and Symptoms

Leave comments or suggestions here, there or somewhere


Wednesday, August 18, 2010

REMAIN up to date with MS News and Information



   

MSVN was founded in 2008. This organization helps those affected by Multiple Sclerosis to obtain information.

Whether an MS patient, a caregiver or a medical professional:  
If you are not yet receiving the weekly MS e-Newsletter, titled "Stu's Views and MS News", or having access to our website and MS blog, then please consider registering after reading the information found below:

Enter a place where information and knowledge is provided for anybody affected by Multiple Sclerosis.
This includes the patients, caregivers, medical providers and/or anybody just interested in having availability to MS information.

Unique in what we do by Bridging the information gaps from all major MS organizations. 

On our website's homepage (http://www.msviewsandnews.org), you will find a link to register for our website and weekly publication of "Stu's Views and MS News", an MS e-Newsletter, which is being received by e-recipients around the globe.

Other features of the MS Views and News website includes:
* Our MS Resources section where you will find our MS Resource weblinks and our MS video library. 
* Find our articles from Ask the MS Nurse and an Occupational Therapist
* Review our menu items on CCSVI and Stem Cell information
* Additionally, find and click the link found on the left side of homepage to view our Library of MS Archives. 
* MS Facts and information is available in (11) different languages.
 (This is beneficial for MS patients or family members/caregivers, who don't read English, but need Multiple Sclerosis information).

A Must see is our MS BLOG (http://wwwmsviewsandrelatednews.blogspot.com/), where you will find easy-to-read MS articles. From this blog you will have access to many other MS informational resources and organizations as well as other MS bloggers.  Find the category listings and other links found on the right side column of this blog to help you to better understand Multiple Sclerosis.

Once registered at our website, you will begin receiving our weekly MS e-Newsletter, called: “Stu’s Views and MS News” and you will have access to our bi-weekly MS Podcasts.

MS Views and News, Inc., strives to keep those affected by Multiple Sclerosis, informed and up-to-date with MS information.

Contact Stuart to learn how you can follow us on FaceBook, Twitter, Medpedia, and Linked-In.
If you have any information, questions or comments, please send an email to: stuart@msviewsandnews.org


Best Wishes,
 Stuart Schlossman
President and Founder of MS Views and News, Inc. 
Editor of: “Stu's Views and MS Related News” 

Our Mission:  MS Views and News’ is dedicated to the global collection and distribution of current information concerning Multiple Sclerosis. In collaboration with other organizations, ‘MS Views and News’ uses state-of-the-art communication channels to provide information for those affected by, or interested in MS.


"MS Views and News" (MSV&N) is a 501©(3) organization as recognized by the Internal Revenue Service

Updated August 2010

Saskatchewan won't wait for national consensus on MS study

By Hannah Scissons, Saskatoon StarPhoenix - August 17, 2010

SASKATOON — It's great news that Manitoba is calling for nationwide clinical trials of a controversial treatment for multiple sclerosis, Saskatchewan's health minister said Tuesday, but the province isn't going to wait for consensus before funding its own trials.


Don McMorris was among provincial and federal health ministers who received a letter this week from Manitoba Health Minister Theresa Oswald, seeking support for a "pan-Canadian randomized clinical trial of the efficacy of the so-called liberation procedure."


"It's an interesting request and we're not opposed to it," said McMorris.


"But . . . I do know that by the time we get 10 provinces, three territories and a federal government all on the same page on this, as far as extent, cost, that is going to take quite a while — whereas we can lead here in Saskatchewan."


Premier Brad Wall announced last month the province is willing to fund clinical trials of the treatment, based on a theory of Italian neurologist Dr. Paolo Zamboni that MS is related to narrowed or blocked veins in the neck.

Read more 


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Fatigue is one of the most common symptoms of Multiple Sclerosis

Source: National MS Society


Fatigue is one of the most common symptoms of MS, occurring in about 80% of people. Fatigue can significantly interfere with a person's ability to function at home and at work, and may be the most prominent symptom in a person who otherwise has minimal activity limitations. Fatigue is one of the primary causes of early departure from the workforce.

What Makes MS Fatigue Different?

Several different kinds of fatigue occur in MS. For example, people who have bladder dysfunction (producing night-time awakenings) or nocturnal muscle spasms, may be sleep deprived and suffer from fatigue as a result. People who are depressed may also suffer fatigue. And anyone who needs to expend considerable effort just to accomplish daily tasks (e.g., dressing, brushing teeth, bathing, preparing meals) may suffer from additional fatigue as a result.

In addition to these sources of fatigue, there is another kind of fatigue—referred to as lassitude—that is unique to people with MS. Researchers are beginning to outline the characteristics of this so-called "MS fatigue" that make it different from fatigue experienced by persons without MS.

Generally occurs on a daily basis
May occur early in the morning, even after a restful night’s sleep
Tends to worsen as the day progresses
Tends to be aggravated by heat and humidity
Comes on easily and suddenly
Is generally more severe than normal fatigue
Is more likely to interfere with daily responsibilities
MS-related fatigue does not appear to be directly correlated with either depression or the degree of physical impairment.


Cause of Fatigue in MS Remains Unknown

The cause of MS fatigue is currently unknown. Ongoing studies are seeking to find an objective test that can be used as a marker for fatigue and for precise ways to measure it. Some people with MS say that family members, friends, co-workers, or employers sometimes misinterpret their fatigue and think the person is depressed or just not trying hard enough.


Continue reading directly from the Source

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Stem Cell Research updates

From Julie Stachowiak, Ph.D., your Guide to Multiple Sclerosis 

This was intended to go out last week, but a glitch delayed it. In that time, I have received some comments about the ISSCR indicating that not everyone thinks they are unbiased scientists. Take a look at the blog below and see what you think (and leave a comment in the blog comment section - help us all out if you are "in the know" or have an opinion).

(From last week:) Check this out - a professional organization, The International Society for Stem Cell Research, has become tired of all the claims of "cures" and "treatments" offered by so-called stem cell clinics. They have set out to educate potential patients with educational materials and questions to ask, as well as look into the patient protections offered by the clinics themselves. They are doing this to keep stem cell science reputable and to help people make good choices, not to limit them.

I wish someone would do this with places offering CCSVI diagnostics and treatments, as well as maintain a database of outcome data - in other words, follow what happens to all of these folks getting treated in other countries (as well as in the US). Since clinical trials are just getting started and demand far outstrips spaces, a collection of case reports (the good and the bad, as well as the neutral outcomes) would start to give us a much more comprehensive picture than the "miracle stories" and couple of "tragedies" that we see on YouTube and portrayed in the media. Just a thought. Take care of yourselves, my friends.
 

Learn More About Stem Cell Research and Treatment 

This is a great initiative. The International Society for Stem Cell Research has recently started a a the ISSCR Task Force on Unproven Stem Cell Treatments to investigate individual clinics that claim to be providing stem cell treatments and cures. Called "A Closer Look at Stem Cell Treatments," their website gives people the opportunity to submit the name of clinics for review. From what I understand, the Society is not going to look at patient outcome data, but really wants to make sure that patients' rights are protected and that the clinics are being supervised by regulatory bodies in their countries or regions. Read more...  



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Tuesday, August 17, 2010

Multiple Sclerosis Myelin Related: Saving the brain's white matter with mutated mice

Tel Aviv University develops genetically mutated stem cells for myelin research



Vanishing White Matter (VWM) disease is a devastating condition that involves the destruction of brain myelin due to a mutation in a central factor. To understand the disease and test potential treatments that could apply to other disorders, such as multiple sclerosis, Prof. Orna Elroy-Stein of Tel Aviv University's Department of Cell Research and Immunology is leading a scientific breakthrough by developing laboratory mice which carry the VWM mutation -- an important new tool.


The mice harbor a mutation of the eIF2B enzyme, which regulates protein synthesis in every cell throughout the body. The key to the new development, says Prof. Elroy-Stein, was the use of genetically-engineered embryonic stem cells to introduce the mutation.


The brain is made up of two components: grey matter, or nerves, and white matter, or glial cells which support the nerves and produce myelin, which wraps around and protects nerve extensions. Recently described in the prestigious journal Brain, the creation of these mutated mice allows for new research on VWM diseases, which trigger loss of myelin in the brain, leading to paralysis and possible death.

Read more. Click Here

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