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Friday, December 10, 2010

Lipoatrophy, Mitoxantrone for Secondary Progressive Multiple Sclerosis, and more - from International Journal of MS Care - Winter Issue


Information provided by: Cherie C. Binns RN BS MSCN

  
Here is the listing of this issue's contents.
Editorial
Lael Stone, MD, Editor-in-Chief  

Said Masri, MD; Andreas Blodau, MD; Norbert Zessack, PhD; Michael Lang, MD 

Linda Moore, EdD, MSN, APRN, MSCN; Michael Kaufman, MD; Jill Conway, MD

Anthony A. Gaspari, MD; Colleen Harris, MN, NP

Preventive Screening in People with Multiple Sclerosis
Megan Weigel Barrett, DNP, ARNP, MSCN; Beverly Roberts, PhD, FAAN, FGSA

Best Practices in Skin Care for the Multiple Sclerosis Patient Receiving Injectable Therapies
Lynn McEwan, NP, MScN, MSCN; Janet Brown, RN, MSCN; Josée Poirier, BSc, MSCN; Janene Spring, RN, BScN, MSCN; Judith Brouillette, RN, BSc, MScN, MSCN; Kathleen Carr, RN, MSCN; Christine Guérette, RN, BSc, MBA, MSCN; Colleen Harris, MN, NP, MSCN; Donna Howard, RN, BScN, MSCN; Diane Lowden, NMSc(A), MSCN; Nicolee Richard, BScN, MSCN

Health-Related Quality of Life Among Young Adults with Multiple Sclerosis
Robert J. Buchanan, PhD; Chunfeng Huang, PhD; Michael Kaufman, MD

A Novel Application of Acceptance and Commitment Therapy for Psychosocial Problems Associated with Multiple Sclerosis
Sean C. Sheppard, MA; John P. Forsyth, PhD; Edward J. Hickling, PsyD; JeanMarie Bianchi, BA
 
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Thursday, December 9, 2010

Teva multiple sclerosis pill shines in big study


Thu Dec 9, 2010 1:27pm GMT
* Teva hopes for U.S. regulatory green light in 2 years
* Teva developing laquinimod drug with Active Biotech
* Laquinimod a rival to new Novartis pill Gilenya


JERUSALEM, Dec 9 (Reuters) - Teva Pharmaceutical Industries expects its pill-based treatment for multiple sclerosis to receive U.S. regulatory approval within two years after a clinical trial met its main goal, it said on Thursday.

Laquinimod, being developed with Sweden's Active Biotech , is jockeying for position in the emerging field of oral treatments for multiple sclerosis (MS), where Novartis's  recently approved Gilenya is the current leader.



READ MORE...



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Purple fruit health claims are premature

Eating purple-coloured fruit such as blueberries “could help ward off Alzheimer’s, Multiple Sclerosis and Parkinson’s”,The Daily Telegraph has reported. The newspaper says the foods act by soaking up harmful iron compounds.

This theory is based on a scientific paper that looked at the chemical and biological actions of iron and chemicals that bind to it. The author summarises a body of evidence that suggests that a form of iron may play a role in many different diseases, also providing a number of simple predictions of how this might occur.

Crucially, this paper only presents a theory, and we do not yet know if the theory is true. Foods that might react with iron, such as blueberries, are also only mentioned in passing in this paper. Stronger evidence is needed to see whether iron plays a role in the development of diseases such as Alzheimer’s disease. If it does, this could be followed by studies looking at how food might intervene in the actions of iron.



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Keep Informed and up-to-date with information concerning
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Wednesday, December 8, 2010

Impact of pediatric multiple sclerosis varies by race


New research has just been released, shining a startling new light on the subject of pediatric multiple sclerosis (MS), a chronic neurological disorder of the brain, spinal cord and optic nerves. 
MS affects some cognitive functions more severely in black children than white children, according to the study published by an interdisciplinary team at the University of Alabama at Birmingham (UAB) in the Dec. 7 issue of Neurology magazine.
The UAB researchers say their report is the first to reveal that the severity of cognitive difficulties in pediatric MS may vary between black and white children. The results reportedly provide valuable insight that could help individualize treatments for children suffering from the disease.
“We don’t yet understand the biological reasons, but the bottom line is treatment options must be re-evaluated and be aggressive enough, especially with black patients, to prolong quality of life for as long as possible,” says Kelly Ross, M.A, a psychology doctoral degree candidate in the UAB College of Arts and Sciences and lead author of the study.




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Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
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ONLINE RESEARCH STUDY for: Patients with Multiple Sclerosis and Caregivers


A study is being conducted to investigate the symptoms of dysphagia, or swallowing disorders, in people with MS.

·        Dysphagia can impact a person’s health and quality of life.
·        Information about the perception of difficulty swallowing can help prevent problems caused by this disorder.


If you are a person with MS between the ages of 18-70 who wishes to volunteer for this study, both you and your caregiver or loved one may complete a brief questionnaire online.

Participation is voluntary and is not affiliated with MS News and Views or Stu's Views and MS News.

* Both you AND your caregiver/loved one should complete the questionnaire using the instructions below:

1.     You and your family member/caregiver will select a 3-digit code to enter on the questionnaires.  It is essential that you both use the SAME 3-digit code so that your questionnaires will be linked to each other. 

For example, you both enter the 3-digit code, “123”on your questionnaires.

2.     You, the individual with MS, will go to:

Your family member/caregiver will go to:

*The questionnaire will prompt you to enter your shared 3-digit code.



This study has been approved by the IRB at Southern Connecticut State University.







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Keep Informed and up-to-date with information concerning
 Multiple Sclerosis when registered at
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Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
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The Value of Time - a Patient's Story

The Value of Time - written by Susan Dorne, OT

I’m hanging on tight, hearing the engines roar, and feeling the vibrations as my time machine comes to a screeching halt!  I see my last article was in 2009 and here we are entering 2011. Seriously, could it go any faster?

As I seem to reiterate the same thing each year, I’m learning more and more about the value of time. Something I so easily lose track of and wonder if I’m making the most of it.

We are all given the same amount of time each day but what we do with it is simply up to us.  I do realize there are many things out of our control but I believe there is just as much or perhaps even more that is.  It may be the need to recognize or be aware of it, slowing down just to see. 






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 Multiple Sclerosis when registered at
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Could fending off Alzheimer's Disease and Multiple Sclerosis, be possible by Eating purple fruit

The Telegraph -  7:00AM GMT 08 Dec 2010


Eating purple coloured fruit such as blueberries could help ward off Alzheimer’s, Multiple Sclerosis and Parkinson’s because it soaks up harmful iron compounds, new research suggests.



Research from Professor Douglas Kell, at the University of Manchester, has found that the majority of debilitating illnesses are in part caused by faulty compounds of iron which cause the production of dangerous toxins that damage the body.
These toxins, called hydroxyl radicals, cause degenerative diseases of many kinds in different parts of the body.
In order to protect the body from these dangerous varieties of poorly-bound iron, it is vital to take on nutrients, known as iron chelators, which can bind to the iron tightly and detoxify it.


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 Multiple Sclerosis when registered at
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Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
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Small, Early Study Suggests Skin Patch Can Suppress MS Immune Activity

Dec  2010

A small study in people with relapsing-remitting MS showed that applying a skin patch containing components of myelin, the material that surrounds nerve fibers and is the target of immune attacks in MS, succeeded in suppressing immune activity. Maciej Juryńczyk MD, Krzysztof Selmaj MD, PhD (University of Lodz, Poland) and colleagues report their findings in Annals of Neurology. (2010;68:593-601) Further studies will be needed to determine whether this approach is safe and effective for treating MS.
Background: Multiple sclerosis involves immune attacks launched against the brain and spinal cord. A main target of this attack is myelin, the substance that insulates nerve fibers and facilitates proper nerve impulse conduction. Researchers have long explored whether the immune system could be trained to ignore myelin by inducing “tolerance.” One approach is to inducing tolerance is to injecting people with MS with myelin peptides, that is, fragments of proteins found in myelin. 
The results of such studies in MS have been mixed and have not yet shown this to be a safe and effective therapeutic strategy, although work in this area continues. For example, a previous large clinical trial of orally administered myelin protein altered some immune activity but was clinically ineffective, as was a more recent clinical trial of an injected myelin peptide in secondary-progressive MS.
The Study: In this placebo-controlled study, the team enrolled 30 people with relapsing-remitting MS (http://nationalmssociety.org/about-multiple-sclerosis/relapsing-ms/relapsing-remitting-ms-rrms/index.aspx). Treatments were administered via an adhesive patch placed on the right upper arm. Participants were randomly assigned to receive either an inactive placebo patch; a patch containing a mixture of 1 mg each of proteolipid protein (PLP), myelin oligodendrocyte protein (MOG), and myelin basic protein (MBP) peptides; or a mixture containing 10 mg each. The patches were changed once each week for four weeks, and then once each month for 11 months. Immune cell reactions were determined via skin biopsies and blood samples. The study was not designed to detect a clinical impact of the treatment, but rather to look for signs of altered immune responses


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Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
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