MS Views and News Be empowered with MS views and news. To receive The MS BEACON e-Newsletter, CLICK HERE - -

Visit our MS learning channel on YouTube, which provides hundreds of MS educational videos presented by MS Experts from across the USA. Archived here: www.youtube.com/msviewsandnews -- Also please visit our Social media platforms: Facebook, Twitter, and Instagram . Each providing important information for the MS community. Furthermore, scroll down the left side of this blog to learn from the resources and links.

Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, for your personal knowledge and to keep you informed of current health-related issues. It is not a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~


Saturday, October 22, 2011

Cognitive Decline, Brain Atrophy More Rapid for Men With MS


October 20, 2011 (Amsterdam, the Netherlands) — A new investigation finds that 6 years after diagnosis, brain volumes and, particularly, cognition were more severely affected in men with multiple sclerosis (MS) than in women with the disease.
White and grey matter atrophy was present in all patients, and deep grey matter structures were also affected, but again particularly in men, the researchers, with lead author Menno M. Schoonheim, a PhD candidate from the Neuroscience Campus Amsterdam, Department of Radiology, VU University Medical Center, Amsterdam, the Netherlands, report.
Thalamic atrophy was most related to cognitive dysfunction out of all the brain structures investigated, Mr. Schoonheim added, and this atrophy was present in both men and women. However, the cognitive effect of the atrophy was mostly seen in the men. Volume changes in the right thalamus best predicted cognition, the authors note, and results were "clearly different" between the sexes.
"This highlights again that gender is important, not only in predisposition but also in clinical progression and cognitive status," Mr. Schoonheim concluded. "However, longitudinal studies are needed to investigate the progression throughout the disease, because this is still a cross-sectional study."
Their results were presented during the Young Scientific Investigators session here at the 5th Joint Triennial Congress of the European and Americas Committees for Treatment and Research in Multiple Sclerosis (ECTRIMS/ACTRIMS).
Grey and white matter atrophy is common in MS, as is cognitive dysfunction, the authors point out. MS is known for its sex effects, with women being more susceptible to the disease, but with men generally facing a worse prognosis.
However, few studies have looked at specific sex effects on atrophy, the authors note. In this study, the researchers investigated the relationship between atrophy and cognition in MS, "focusing on modification of this relationship by gender."
Structural 3T magnetic resonance imaging, including 3DT1 for brain volumes, and cognitive evaluations were performed in 50 healthy control patients (20 men) and 120 patients with relapsing-remitting MS (40 men), part of an early-inception cohort, 6 years postdiagnosis. Sex groups were comparable with regard to age, education level, disability, lesion volume, and disease duration.
Normalized grey matter, white matter, and whole-brain volumes, corrected for head size, were calculated using a method called SienaX, and all subcortical grey matter volumes were determined using FIRST, a method that analyzes brain regions including the thalamus, caudate nucleus, putamen, and others, and provides measures of both right and left structures.

Continue reading from Medscape - registration required


===========================================================
Remain CURRENT with Multiple Sclerosis news and information  
Providing You with MS Views and News, is what we do 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
On the Fourth Wednesday of Each Month
Visit: StuMSradio - With Deanna and Stu
 CALL-IN To listen, speak with us or speak with a guest
* Call (347) 215-9265 *
or click: Multiple Sclerosis-UnPlugged to listen online
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
Help us to educate $ DONATE NOW PLEASE $
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
..............................

No comments: