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Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

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Saturday, July 23, 2011

New multiple sclerosis research avenues opened, scientists say

Healthcare News
22/07/2011
Recent research will allow new types of research to be done into multiple sclerosis, research shows.
Multiple sclerosis research has taken a step forward thanks to new findings which could bring hope to many people using assisted livingto cope with the condition.

A team from Ohio State University have created a new cell-culture system related to mechanisms which take effect in those with multiple sclerosis.

This system, which allows two types of cells to interact in the laboratory as they would in nature, will allow scientists to study how myelination is switched on and off.

Chen Gu, lead author, explained: "This channel is important because it is what leads to electrical activity and how neurons communicate with each other downstream.

"If that process is disrupted by demyelination, disease symptoms may occur."

In other news, a Scripps Research Institute study has halted multiple sclerosis in mice through the use of a compound which shuts down white blood cell TH17 which malfunctions in those with the condition.

Read about Barchester expertise in offering multiple sclerosis support.
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Remain CURRENT with Multiple Sclerosis news  and information, 
when registered at our  MS Views and News website
.
.Providing You with 'MS Views and News', is what we do 
.
On the 4th Wednesday of each month  
Listen-to StuMSRadio.com at 8pm eastern time.
Each month will feature various guests to be interviewed
Call-in to have (5) minutes of airtime.
Speak about your MS or ask questions 
.
Your donation will Help us to educate

"MS Views and News" is a 501©(3) Not-for-Profit organization as recognized by the Internal Revenue Service 
.. All contributions are tax deductible to the fullest extent allowed by law 
.===========================================================
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

Friday, July 22, 2011

Are Newer MS Drugs Worth Their High Price Tag?

By Amanda Gardner
HealthDay Reporter
 | HealthDay






THURSDAY, July 21 (HealthDay News) -- Newer "biologic" drugs for multiple sclerosis do benefit some patients, a new study finds, but they are extraordinarily expensive and may not be cost-effective when compared to more basic treatments.
That's not to say that people with MS should not be taking these so-called disease-modifying therapies (DMTs) -- such as interferon or Tysabri. Rather, moves should be made to make the drugs more affordable, the researchers said.
Although these drugs aren't a cure, "they delay disease progression [and are] the best we can do at this point," explained Katia Noyes, lead author of a paper appearing in the July 20 online issue of Neurology. And right now, she noted, "these medications are available in European countries for about one-third of the cost as in the U.S."
The authors noted, for example, that in 2010 a year's supply of one type of interferon drug would cost an estimated $12,000 in the United Kingdom, compared to $34,000 in the United States.
Lowering U.S. prices by two-thirds (67 percent) would make the drugs much more cost-effective, the authors stated. So would starting the medications earlier, so as to better stave off MS-linked disability.
"This in no way suggests that anyone appropriate for treatment should not be on it, [but] the study reminds us that costs of the therapies, particularly the out-of-pocket costs for people with MS, are an important consideration," said Nicholas LaRocca, vice president for health care delivery and policy research at the National Multiple Sclerosis Society (NMSS) in New York City.
The NMSS was one of the study's sponsors.
The drugs can typically cost about $30,000 a year, said Noyes, who is associate professor and division chief of health policy and outcomes research at the University of Rochester Medical Center.
According to the NMSS, about 400,000 people in the United States have multiple sclerosis, about 85 percent of whom have relapsing-remitting MS, for which DMTs are used.
The authors' model was based on data on 844 people with relapsing-remitting MS in the United States. It took into account not only the cost of DMTs, but also hospital and office-based care, diagnostic tests, nursing home costs and time taken off from work.
According to the investigators' calculations, DMTs represent about half of all health care costs over 10 years for a person with MS.
And overall, the health gains seen from these medications were "modest," the authors stated.
For instance, people taking interferon beta-1b experienced an average of about six years with no relapses over the course of a decade, compared to five years without relapses for those not taking DMTs.
Still, the benefits were highly variable between individuals.
"Everyone with MS is different and although some people derive modest benefit from therapy, others benefit greatly and are able to continue working and living a full and active life because of their therapy," LaRocca said.
And the study didn't look at other aspects of disease progression, such as how severe the relapses were, or the timing, which would also affect quality of life.
"We may be ready to think about some mechanisms of controlling pharmaceutical prices. Most countries have these mechanisms in place," said Noyes. "[Or] maybe there should be a push for developing more effective medications."
An accompanying editorial pointed out that costs may naturally go down with the advent of more oral DMTs (as opposed to the injectables that are primarily in use now) and as drug company patents expire and generics are introduced.



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Remain CURRENT with Multiple Sclerosis news  and information, 
when registered at our  MS Views and News website
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.Providing You with 'MS Views and News', is what we do 
.
On the 4th Wednesday of each month  
Listen-to StuMSRadio.com at 8pm eastern time.
Each month will feature various guests to be interviewed
Call-in to have (5) minutes of airtime.
Speak about your MS or ask questions 
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Your donation will Help us to educate

"MS Views and News" is a 501©(3) Not-for-Profit organization as recognized by the Internal Revenue Service 
.. All contributions are tax deductible to the fullest extent allowed by law 
.===========================================================
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

Less Common Symptoms of Multiple Sclerosis

The National MS Society
and MS Learn Online present:

A Feature Presentation:


An interview with
Dr. Stephen Krieger on:
  • What are some less common symptoms?
  • Can they be managed?
  • How can you tell if it's an MS symptom?

Click here to view the webcast, or copy into your browser: http://www.nationalmssociety.org/multimedia-library/ms-learn-online/index.aspx..





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Remain CURRENT with Multiple Sclerosis news  and information, 
when registered at our  MS Views and News website
.
.Providing You with 'MS Views and News', is what we do 
.
On the 4th Wednesday of each month  
Listen-to StuMSRadio.com at 8pm eastern time.
Each month will feature various guests to be interviewed
Call-in to have (5) minutes of airtime.
Speak about your MS or ask questions 
.
Your donation will Help us to educate

"MS Views and News" is a 501©(3) Not-for-Profit organization as recognized by the Internal Revenue Service 
.. All contributions are tax deductible to the fullest extent allowed by law 
.===========================================================
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

New Australian research has found a link between glandular fever and multiple sclerosis (MS).

Medical reporter Sophie Scott
Posted July 22, 2011
MS affects 20,000 people in Australia and is a condition where the immune system attacks the brain and spinal cord.
Many of those diagnosed are young, healthy women.
Now a new study from the Australian National University (ANU) has found those who have glandular fever antibodies have a much greater risk of developing multiple sclerosis.
The research, published in the journal Neurology, could lead to new treatments for the condition.
ANU Associate Professor Robyn Lucas studied 300 patients with MS and 500 healthy participants.
She also found a strong relationship between those who had MS and genetic changes relating to the immune system.
Professor Lucas says the findings are consistent with other studies showing an association between markers of past episodes of glandular fever and MS risk.
"We have shown further interaction with other immune system genes in the HLA class 1 region and CLTA-4," she said.
Professor Lucas says the Australian work is promising.
"It starts to bring together the different risk factors that we know are involved in MS. It points us in the right direction for further research to prevent and cure MS," she said.
The research was part of the Ausimmune study, a major study looking at the possible environmental triggers for multiple sclerosis.

Source: ABC News-au



===========================================================
Remain CURRENT with Multiple Sclerosis news  and information, 
when registered at our  MS Views and News website
.
.Providing You with 'MS Views and News', is what we do 
.
On the 4th Wednesday of each month  
Listen-to StuMSRadio.com at 8pm eastern time.
Each month will feature various guests to be interviewed
Call-in to have (5) minutes of airtime.
Speak about your MS or ask questions 
.
Your donation will Help us to educate

"MS Views and News" is a 501©(3) Not-for-Profit organization as recognized by the Internal Revenue Service 
.. All contributions are tax deductible to the fullest extent allowed by law 
.===========================================================
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.