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Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, for your personal knowledge and to keep you informed of current health-related issues. It is not a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

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Saturday, October 15, 2011

Researchers Recruiting 5,000 First-Degree Relatives of People with MS for Genetic/Environmental Research Study


LARGE GENETIC RESEARCH study for relatives of MS Patients 




A group of researchers at Harvard Medical School, Brigham and Women’s Hospital, and Partners Multiple Sclerosis Center are conducting a new research study entitled “Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis Susceptibility,” for short “Genes and Environment in Multiple Sclerosis” (GEMS). 

The purpose of this study is to identify the genetic, environmental, and immune profiles that may increase a person’s risk of developing multiple sclerosis (MS). While MS is not a disease caused by a single variation in genetic material (DNA) or a single malfunction in immune cells, there are both genetic and immunologic alterations that make the development of MS more likely. Obtaining information about who is at risk for MS will be beneficial in the future if we can identify effective ways to prevent or slow down the progression of this disease.


This large research study involves subjects (between the ages 18-50) who are at risk of developing MS. First degree relatives of patients with MS are being asked to take part in this research study because they might be at a slightly increased risk of developing MS when compared to the general population. First-degree relatives are eligible regardless of whether they have a diagnosis of MS.   We are interested in developing tests that can help predict who might develop MS in the future.

Participation in the study involves answering an online questionnaire and providing a saliva sample by mail, therefore, participants can reside anywhere in the United States and no travel is required. Participants also have the option to donate blood or undergo an MRI study of the brain.

For more information about participating, visit their facebook page: http://bitly.com/GEMSstudy.






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Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

Thursday, October 13, 2011

From New Zealand, an MS Patient describes his MASSIVE Improvement

An MS Patient wishes to inform the world how his life with debilitating Multiple Sclerosis has improved


Click the links found here:



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Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

Current MS Medications Previously Approved and Medications under review or in research



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Remain CURRENT with Multiple Sclerosis news  and information 
REGISTER HERE   MS Views and News 
.
.Providing You with 'MS Views and News', is what we do 
.
On the 4th Wednesday of each month  
Listen-to StuMSRadio Online at 8pm eastern time.
Each month will feature various guests to be interviewed
Call-in to have (5) minutes of airtime.
Speak about your MS or ask questions 
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"MS Views and News" is a 501©(3) Not-for-Profit organization as recognized by the Internal Revenue Service 
.. All contributions are tax deductible to the fullest extent allowed by law 
.===========================================================
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

Tuesday, October 11, 2011

Natalizumab (Tysabri) Effective for Relapsing-Remitting MS

Natalizumab is well tolerated and reduces relapses and disability at two years in patients with relapsing-remitting multiple sclerosis, according to a review published online Oct. 5 in the Cochrane Database of Systematic Reviews.




MONDAY, Oct. 10 (HealthDay News) -- Natalizumab (NTZ) is well tolerated and reduces relapses and disability at two years in patients with relapsing-remitting multiple sclerosis (RRMS), according to a review published online Oct. 5 in the Cochrane Database of Systematic Reviews.


Eugenio Pucci, Ph.D., from Ospedale di Macerata in Italy, and colleagues reviewed available literature through Feb. 19, 2010, to evaluate the efficacy, tolerability, and safety of NTZ in the treatment of patients with RRMS. Three randomized trials were included: one placebo-controlled and two add-on placebo-controlled studies, involving a total of 2,223 participants.


The investigators found conclusive data for efficacy and tolerability, but not for safety. There was statistically significant evidence showing that NTZ was efficacious for both primary and secondary outcomes. Compared to a control group, NTZ reduced the risks of experiencing at least one new exacerbation and of experiencing progression at two years by approximately 40 and 25 percent, respectively. Statistical evidence from MRI parameters favored the use of NTZ. During the two-year follow-up NTZ was well tolerated, and there was no difference between NTZ-treated patients and controls regarding the number of patients experiencing at least one adverse event (AE). Progressive multifocal leukoencephalopathy (PML) was identified in two patients: one had received 29 doses and the other 37 doses of NTZ. The risk of rare and long-term AEs, including PML, cancers, and other opportunistic infections, could not be sufficiently evaluated by this protocol.



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===========================================================
Remain CURRENT with Multiple Sclerosis news  and information 
REGISTER HERE   MS Views and News 
.
.Providing You with 'MS Views and News', is what we do 
.
On the 4th Wednesday of each month  
Listen-to StuMSRadio Online at 8pm eastern time.
Each month will feature various guests to be interviewed
Call-in to have (5) minutes of airtime.
Speak about your MS or ask questions 
.

"MS Views and News" is a 501©(3) Not-for-Profit organization as recognized by the Internal Revenue Service 
.. All contributions are tax deductible to the fullest extent allowed by law 
.===========================================================
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

Reduced Loss of Brain Volume in Multiple Sclerosis Patients Treated with COPAXONE®


Five-year Study Findings Published in the Journal of the Neurological Sciences
JERUSALEM, Israel--Results from a five-year study of treatment-naïve patients with relapsing-remitting multiple sclerosis (RRMS) demonstrated that patients treated with COPAXONE® (glatiramer acetate injection) showed significant reduced loss of brain volume compared to patients treated with other disease modifying therapies (DMTs).
Though all DMT treatment arms resulted in a reduction in brain volume loss compared to the control group of non-treated patients, COPAXONE® had a significantly better effect than both low and high dose interferons, in reducing loss of brain volume. A paper published by Dr. Omar Khan, detailing the study findings, “Effect of disease-modifying therapies on brain volume in relapsing–remitting multiple sclerosis: Results of a five-year brain MRI study,” was recently published in the Journal of the Neurological Sciences.
“These data represent the importance of ongoing research in a practical clinical setting to better understand multiple sclerosis and the impact of therapy on the course of the disease ,” said Jon Congleton, Senior Vice President and General Manager, Teva Neuroscience. “Not only does this study highlight the benefit of COPAXONE® in reducing brain volume loss, it underscores the value of early treatment in influencing long-term outcomes.”
Brain volume loss in multiple sclerosis patients exceeds the rate of healthy control groups. Brain volume loss, sometimes referred to as atrophy, may be correlated with cognitive and physical deficits. Modern magnetic resonance (MR) techniques can reliably measure loss of brain volume over time.
ABOUT THE STUDY
In the study, the COPAXONE® treatment arm resulted in a -2.27 percent change in brain volume (PCVB) as compared to baseline versus -2.62 percent for Avonex® (low-dose interferon), -3.21 percent for Betaseron®/Rebif® (high-dose interferon).

===========================================================
Remain CURRENT with Multiple Sclerosis news  and information 
REGISTER HERE   MS Views and News 
.
.Providing You with 'MS Views and News', is what we do 
.
On the 4th Wednesday of each month  
Listen-to StuMSRadio Online at 8pm eastern time.
Each month will feature various guests to be interviewed
Call-in to have (5) minutes of airtime.
Speak about your MS or ask questions 
.

"MS Views and News" is a 501©(3) Not-for-Profit organization as recognized by the Internal Revenue Service 
.. All contributions are tax deductible to the fullest extent allowed by law 
.===========================================================
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.