MS Views and News Be empowered with MS views and news. To receive The MS BEACON e-Newsletter, CLICK HERE - -

Visit our MS learning channel on YouTube, which provides hundreds of MS educational videos presented by MS Experts from across the USA. Archived here: www.youtube.com/msviewsandnews -- Also please visit our Social media platforms: Facebook, Twitter, and Instagram . Each providing important information for the MS community. Furthermore, scroll down the left side of this blog to learn from the resources and links.

Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, for your personal knowledge and to keep you informed of current health-related issues. It is not a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~


Thursday, January 12, 2012

MS and 100 Pounds Fade Away Eating Mostly Raw, Vegan Diet


I can somewhat agree with what this person is writing, concerning her veggie diet
=====================================


Written by: Sandy Henson Corso


I have been on a serious health journey for more than three years now. Here is my story. This is going to be a shocker because lots of people don't know this entire story. Even some of my family and closest friends don't know what I have been through with regard to my health. I will share the details in hopes of inspiring people to eat more plants and fewer animals. 

In 2000 I was diagnosed with Multiple Sclerosis. It was a very, very dark and scary time. When I tell you I got down lots on my hands and knees and prayed for God's help I am not exaggerating! I was scared, very scared. I walked around like a zombie for years. Then I went on about my life, getting married, buying a house, having two beautiful children. After all this, about 3.5 years ago, I was still really scared. I was not feeling good, I had an IV in my arm receiving intravenous steroids, and I was more than 100 pounds overweight. Plus, every day I had to have my husband give me my medication, which was a shot, for my MS. How could this happen? I was in a dark place.

So I decided to make a change. I went to a personal trainer named Heidi who happened to move right next door where I was working. The universe works in strange ways. I sat with her in tears: How could this be? How could I have allowed myself to be so unhealthy and so overweight? She was amazing and assured me I would be fine. I worked with her for about eight months. I lost some weight and inches but most importantly I made fitness part of my life. My next step was to join a gym and see if I could keep up my fitness. I joined and I did keep up. I started running races. I did 5k races and then 5-mile races. 

I then decided to go off my MS medication. My instincts have always been right for me. I believe 100 percent in the power of my own healing through diet and exercise. I do supplement with vitamin D3 and B12, which I believe are both very important. I am not saying everyone should go off their medication -- you have to do what YOUR instincts tell YOU. 


READ MORE



~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
..............................

A First Line, Personalized, Treatment for MS completes phase II studies


information provided to us by Thomas Mann

Tovaxin®

Opexa's lead product candidate is Tovaxin, a personalized T-cell vaccine for the treatment of multiple sclerosis (MS) that is specifically tailored to each patient's disease profile. Opexa believes the potential combination of efficacy, superior safety, improved tolerability and patient-friendly administration schedule may position Tovaxin as the MS treatment of choice as compared to existing therapeutic options.
Tovaxin is designed to reduce the number of specific subsets of autoreactive T-cells known to attack myelin. Tovaxin is manufactured using Opexa Therapeutics’ proprietary method for the production of patient-specific T-cell vaccines, which comprises the collection of blood from the MS patient, the harvest and expansion of disease-causing T-cells from the blood, and the return of these expanded, irradiated T-cells back to the patient. These attenuated T-cells, which comprise the Tovaxin vaccine, are reintroduced into the patient via subcutaneous injection to trigger a therapeutic immune system response.
Tovaxin is being developed as a first line treatment for MS. The treatment will consist of donating blood and creating a vaccine using the patient’s own cells. The vaccine cells will be irradiated to render them unable to divide, but able to evoke an immune response. The vaccines will be administered in the doctor’s office as a subcutaneous injection in the arm given five times a year. The first four injections are administered a month apart with the fifth and final injection being administered two months after the fourth. While many other MS treatments have constant side effects such as flu symptoms, injection site problems, and serious adverse events, Tovaxin has not had any treatment related serious adverse events (SAEs). The most common side effect reported form clinical studies has been mild to moderate injection site reaction that usually resolves without treatment within 24 hours. Tovaxin therapy is specific for the immune response against myelin destroying T cells and does not cause a general immunosuppression. Tovaxin may be a strong alternative for subjects who do not want to start hospital infusions or weekly injections, or have not been able to tolerate the side effects or infections of immunosuppressant drugs on the market. 
Tovaxin could represent a viable alternative for patients who:
  • Have chosen to stop or not start treatments;
  • Are newly diagnosed with MS;
  • Are dissatisfied with currently marketed drugs.

 CONTINUE READING



..Comments for each blog posting are always appreciated. 
     Please use the link found below, to leave comments..
.. All comments are moderated to reduce SPAM and bad language
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 Click to: REGISTER For our MS weekly e-Newsletter
"Providing You with 'MS Views and News', IS What We Do"   ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
..............................

Wednesday, January 11, 2012

Study Shows Potential of Lab Test to Detect Virus Which Causes PML in People with MS – ongoing study may help identify risk for PML in people treated with natalizumab



Biogen Idec researchers have published results on a blood test that detects antibodies to the JC virus, the virus responsible for PML (a severe brain infection). PML has emerged in some people who have taken natalizumab (Tysabri,® Biogen Idec and Elan; Read more about natalizumab and PML). This paper (Annals of Neurology 2011;70:742-750) reports that in an ongoing study of 1,096 people in the U.S. with relapsing MS being treated or considering treatment with Tysabri, 56% had evidence of JC virus antibodies. The presence of antibodies indicates that a person has at some point been infected by or exposed to the virus, which usually lies dormant. Ultimately the study may show whether detection of antibodies to JC virus can predict an individual’s risk for developing PML and help guide treatment decisions.
Details: In studies of patients who have developed PML on Tysabri, all of those tested had serum antibodies prior to the onset of PML. The company has been conducting ongoing studies of its two-step laboratory test (called STRATIFY JC virus™) to determine whether the incidence of PML in Tysabri-treated patients is lower in those who do not have detectable antibodies to JC virus.
In this study, called STRATIFY-1, women had a lower prevalence of antibodies than men (53.4% versus 64.3%), and antibodies were more prevalent with older age. The false-negative rate was 2.7%, meaning that in about 3 out of 100 times, the lab test failed to detect JC virus antibodies in patients who had evidence of the virus DNA detected by a urine test.
The company is continuing to test people starting or already taking natalizumab therapy to determine whether the lab test can reliably predict a person’s risk for developing PML, which may help doctors and patients make more informed treatment choices. Read more about the STRATIFY study.

article source: NMSS


..
..Comments for each blog posting are always appreciated. 
     Please use the link found below, to leave comments..
.. All comments are moderated to reduce SPAM and bad language
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 Click to: REGISTER For our MS weekly e-Newsletter
"Providing You with 'MS Views and News', IS What We Do"   ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
Help us to educate $ DONATE NOW PLEASE $

"MS Views and News"  is a 501©(3) Not-For-Profit organization
 as recognized by the Internal Revenue Service

All contributions are tax deductible to the fullest extent allowed by law
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
..............................

Tuesday, January 10, 2012

Spasticity gene finding provides clues to causes of nerve cell degeneration


January 9, 2012
The discovery of a gene that causes a form of hereditary spastic paraplegia (HSP) may provide scientists with an important insight into what causes axons, the stems of our nerve cells, to degenerate in conditions such as multiple sclerosis.
n the  today, an international team of scientists led by Dr Evan Reid at the University of Cambridge, and Dr Stephan Zuchner from the University of Miami, report that mutations in the gene known as 'reticulon 2' on chromosome 19 cause a form of HSP, a condition characterised by progressive  and  (spasticity) of the legs, caused by selective and specific degeneration of axons
The team identified three mutations in the reticulon 2 gene as causing a type of HSP – in one case, this mutation included an entire deletion of the gene. In addition, the researchers showed that reticulon 2 interacts with another gene, spastin.  in this latter gene cause the most common form of hereditary spastic paraplegia.
Reticulon 2 provides the genetic code for a reticulon protein that is a member of a family of proteins recently shown to play a key role in shaping the endoplasmic reticulum. The endoplasmic reticulum is a network of interconnected sheets and tubules that extends throughout the cytoplasm in nearly all cells. It has a number of functions, including protein synthesis, calcium signalling and regulation of other components of the cell. Recent data suggest that the sheets are involved in protein synthesis, whereas the tubules are specialised to carry out the other functions.
This new study provides the most direct evidence to date that defects in how the endoplasmic reticulum is shaped and formed could underlie axon degeneration. When axons degenerate, signals are unable to pass through the , leading to a breakdown of communication within the central nervous system. This is common in degenerative diseases of the nervous system, such as multiple sclerosis.
"Our work highlights important new disease mechanisms, which may provide a platform for us to study how axons are damaged in devastating illnesses such as HSP, and perhaps even in , which in some cases is very similar to HSP," explains Dr Reid, a Wellcome Trust Senior Research Fellow in Clinical Science. "But we must not forget how this work may immediately directly benefit families affected by hereditary spastic paraplegia, for whom the discovery now opens up the possibility of genetic counselling and testing."
Article source: Medical Press
..Comments for each blog posting are always appreciated. 
     Please use the link found below, to leave comments..
.. All comments are moderated to reduce SPAM and bad language
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 Click to: REGISTER For our MS weekly e-Newsletter
"Providing You with 'MS Views and News', IS What We Do"   ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
Help us to educate $ DONATE NOW PLEASE $

"MS Views and News"  is a 501©(3) Not-For-Profit organization
 as recognized by the Internal Revenue Service

All contributions are tax deductible to the fullest extent allowed by law
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
..............................

Common virus may trigger MS nerve damage



FOR the first time we have an answer to what Epstein-Barr virus (EBV) may be doing in the brains of people with multiple sclerosis. RNA from the virus could be triggering the inflammation of nerve tissue characteristic of the disease.
EBV is present in almost all people with MS, and having glandular fever, caused by the virus, is known to increase the risk of developing MS.
To investigate further, Ute-Christiane Meier at Queen Mary University of London and her colleagues performed a post-mortem analysis of the brains of people with and without MS. They detected EBV in damaged areas of the MS brains. Antibody tests showed that the virus hadn't been actively spreading, but it had released small RNA molecules into nearby areas. Further studies showed this RNA could activate the immune system, triggering inflammation, which could damage nerve cells and cause the symptoms of MS (NeurologyDOI: 10.1212/wnl.0b013e31823ed057).
"If we can pinpoint EBV as a trigger, it's possible that we could potentially prevent the condition by treating the virus," says Meier.

article source: New Scientist


..
..Comments for each blog posting are always appreciated. 
     Please use the link found below, to leave comments.. .. All comments are moderated to reduce SPAM and bad language
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 Click to: REGISTER For our MS weekly e-Newsletter
"Providing You with 'MS Views and News', IS What We Do"   ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
Help us to educate $ DONATE NOW PLEASE $

"MS Views and News"  is a 501©(3) Not-For-Profit organization
 as recognized by the Internal Revenue Service

All contributions are tax deductible to the fullest extent allowed by law
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
..............................

Hadasah's Look at Multiple Sclerosis and other Neurologic illnesses




January 2012
Written by Hadassah's New Director General

Recently, Prof. Tamir Ben-Hur, Head of the Department of Neurology, made an outstanding presentation to HMO’s medical management. As I watched the slides that detailed the many aspects of care and treatment his department provides and the research they are pursuing, I thought again about how much the discipline has changed in recent years. In the “old days,” neurology was considered a rather low-keyed field. Neurologists were essentially diagnosticians, analyzing patients’ conditions and providing the best tools to assist them. There were no modalities to immediately cope with stroke victims, or those with epilepsy and immune-mediated diseases that weaken the respiratory muscles. Dealing with the soft tissues of the brain was a frightening prospect.

Today, neurology and neurologists are infused with excitement. Today, as Prof. Ben-Hur pointed out, neurologists intervene at critical moments with protocols and practices that can and do save lives. Today, they are constantly looking forward, revisiting prior concepts and exploring new avenues of research.

Neurological illnesses affect one in every five people. I believe every one of us knows someone, or more than one person, who suffers from the progressive impact of Parkinson Disease, Alzheimer’s, multiple sclerosis or any of the lesser known neurodegenerative diseases. While there are still no know cures, thanks to today's “new” neurology hope is at hand. Molecular medicine and stem cell science have made a major difference, as have new and sophisticated tools and equipment that have significantly changed neurologists’ ability to effectively intervene.

Consider multiple sclerosis, just one of the many neurodegenerative diseases the Neurology Department treats and investigates. Prof. Dimitrios Karussis and his team performed the world’s first clinical trial using the patient’s own stem cells to inhibit the destructive inflammatory process and promote the brain’s recovery. That discovery prompted them to begin preparing for the next stage of clinical trials. The research also involved using the same principle to treat people with amyotrophic lateral sclerosis, also known as Lou Gehrig’s disease. Following conclusive tests on laboratory animals, the research has now moved into a new and exciting phase. A clinical trial on this potential treatment will begin shortly.

To accurately measure the effectiveness of treatment and the impact of multiple sclerosis on visual functions, Dr. Netta Levin and her team have developed new visual tests using functional MRI technologies, electrophysiological data and newly designed computerized dynamic visual function tests. They are now developing the concepts and technology to make it applicable for everyday clinical use.

In collaboration with Prof. Benjamin Reubinoff, Prof. Ben-Hur’s team is developing the use of human embryonic stem cells to treat multiple sclerosis. They believe their research will ultimately lead to the world’s first clinical trial to test this use of human embryonic stem cells.

About 50,000 people in Israel suffer from epilepsy. This year, Hadassah opened a multidisciplinary Epilepsy Center, the only one in the greater Jerusalem area, where neurologists play a vital role. Again, aided by sophisticated equipment, they diagnose, monitor and provide multi-disciplinary treatment to epilepsy patients.

Strokes have a devastating impact on people’s lives and those of their loved ones. Just a short time ago, rehabilitation was their only hope of returning to normal lives.

The approach to stroke victims has progressed from providing diagnoses and medications to prevent the next stroke, to the point where frequently doctors can intervene in the acute event and change the outcome significantly. According to Prof. Ben–Hur, the seemingly "simple" things make the difference in the mortality rate. The correct monitoring and maintenance of patient's blood pressure, body temperature and sugars can produce excellent outcomes.

I have mentioned just a few highlights of what Prof. Ben-Hur conveyed about the 11 neurology research groups, and the work of the same neurologists in the hospital, in the specialized laboratories, in the clinics at Ein Kerem and on Mt. Scopus, and through hospital-based ambulatory medicine. The facts and figures, graphs and charts encompassed every aspect of his department’s activities. His articulate presentation reinforced everyone’s understanding of the energized and effective world of neurology and what Hadassah’s Department of Neurology can offer our patients, now and in the future.

Yours,

Ehud - Prof. Ehud Kokia
Director General




..Comments for each blog posting are always appreciated. 
     Please use the link found below, to leave comments..
.. All comments are moderated to reduce SPAM and bad language
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 Click to: REGISTER For our MS weekly e-Newsletter
"Providing You with 'MS Views and News', IS What We Do"   ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Disclaimer:  'MS Views and News' (MSVN), does not endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
..............................