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Thursday, August 2, 2012
MS Symptom Management and the Urologic Implications of MS. Attend this education program on September 8th in Jacksonville, Fl.,
Dr. Bibiana Bielekova, an investigator at the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, said the discovery helps define the effects of one of the newest drugs -- daclizumab -- under investigation for treating MS.
Read more: http://www.upi.com/Health_News/2012/08/01/Unique-cell-type-in-multiple-sclerosis/UPI-67301343879929/#ixzz22QQLirN7
Wednesday, August 1, 2012
Tuesday, July 31, 2012
Free Webinars Covering Financial Planning, Benefits, and Employment Strategies Specifically for People Living with Multiple Sclerosis Coming this Fall
Based primarily on recent Medscape News coverage, the following slideshow collects some of the more prominent investigations on nutrition and the brain into a single resource to aid in counseling your patients.
A new paper published in the New England Journal of Medicine is the first research to identify a specific immune target in MS, a protein known as Kir4.1. Until this discovery, a specific antigen (a substance that evokes the production of one or more antibodies) in MS has not been found. In this study, the immune response to this target was seen in 47 percent of the people with MS.
Autoantibodies are not the primary cause of MS, but as a secondary response, they may give researchers a better idea of what is causing the breakdown in the central nervous system of people with MS.
For this study, researchers from the Technical University of Munich in Germany obtained serum from 397 people with MS, 329 people with other neurological conditions, and 59 healthy serum donors.
When researchers tested the IgG levels in the blood of the people with MS, they found a very specific reaction to the protein KIR4.1. IgG stands for Immunoglobin G, which is the main antibody found in our blood. Antibodies are major components of the immune system. When something is presented in the body that is seen as foreign, like a virus or bacteria, the immune system goes after the invader, and the white blood cells produce an antibody. This antibody is like a footprint marker leading back to the "invader" – it can tell us what the body sees as foreign.
The researchers found there was an immune system response to KIR4.1 KIR4.1 is a potassium channel protein which is vitally important to myelination, neuronal plasticity, and the inflammatory response.
"We found no significant differences in the prevalences or titers of serum anti-KIR4.1 antibodies among persons with a clinically isolated syndrome, those with relapsing-remitting multiple sclerosis, and those with progressive multiple sclerosis and observed no correlations between KIR4.1 antibody positivity and age, clinical characteristics, or characteristics of the cerebrospinal fluid," the authors wrote.
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