Please visit our MS learning channel on Youtube, which provides hundreds of topics from our education programs, that were video-recorded and archived here: www.youtube.com/msviewsandnews

joomla ecommerce template -- Scroll left side of this blog for needed resources. Also, use our 'search by topic' tool, to find specific information.

Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

=================

CHAMPIONS TACKLING MS - AWARDS Dinner, Honoring Aaron Boster, MD and Jon e. Glaser, DDS - now open for registration. Visit www.events.msvn.org

Tuesday, December 31, 2013

Study finds clues to understanding MS

December 30, 2013
By Bradley J. Fikes7:25 P.M.DEC. 30, 2013

Scientists at the Sanford-Burnham Medical Research Institute have found a possible explanation for the loss of nerve function caused by multiple sclerosis and similar neurodegenerative diseases. The research provides a new approach to finding potential therapies.
A protein called contactin-1 is required to wrap nerves with myelin, a protective sheathing that enables proper function, the scientists found. When myelin is worn away, as in multiple sclerosis, nerves in the brain and spinal cord become damaged and don’t properly transmit sensory and motor signals.
……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

Canada has highest rate of multiple sclerosis in the world

December 30, 2013


LONDON -- It's a disease that strikes down adults at their prime -- and it's found Ground Zero in Canada.

Multiple sclerosis afflicts Canadians at a rate that far outpaces anyplace else in the world, a new survey has found.

"It's really shocking … It is almost like a Canadian disease," said Karen Lee, of the Multiple Sclerosis Society of Canada.

Nearly 100,000 Canadians have the disease, a rate that's 28% higher than the country with the second-highest mark, Denmark, and nine times higher than the global average, according to the survey by the Multiple Sclerosis International Federation.

Read More of this article


……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

Monday, December 30, 2013

Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine

Information shown below, originated from Patients for Stem Cells

Excellent summary on everything your own Mesenchymal Stem Cells can repair. 



Matthew B Murphy1, Kathryn Moncivais1 and Arnold I Caplan2
  1. 1Celling Biosciences, Austin, TX, USA
  2. 2Department of Biology, Skeletal Research Center, Case Western Reserve University, Cleveland, OH, USA
Correspondence: Professor AI Caplan, Department of Biology, Skeletal Research Center, Case Western Reserve University, Cleveland, OH 44106, USA. E-mail:aic@case.edu
Received 8 July 2013; Accepted 22 July 2013
Top

Abstract

Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and immunomodulatory functions that may have the greatest therapeutic impact in vivo. Unlike pharmaceutical treatments that deliver a single agent at a specific dose, MSCs are site regulated and secrete bioactive factors and signals at variable concentrations in response to local microenvironmental cues. Significant progress has been made in understanding the biochemical and metabolic mechanisms and feedback associated with MSC response. The anti-inflammatory and immunomodulatory capacity of MSC may be paramount in the restoration of localized or systemic conditions for normal healing and tissue regeneration. Allogeneic MSC treatments, categorized as a drug by regulatory agencies, have been widely pursued, but new studies demonstrate the efficacy of autologous MSC therapies, even for individuals affected by a disease state. Safety and regulatory concerns surrounding allogeneic cell preparations make autologous and minimally manipulated cell therapies an attractive option for many regenerative, anti-inflammatory and autoimmune applications.

Keywords: 

anti-apoptotic; anti-inflammatory; antimicrobial; mesenchymal stem cell; pericyte; trophic
Top

Introduction

Mesenchymal stem cells (MSCs) have been suggested to be patient-specific drugstores for injured tissue, and with good reason.1 What was originally believed to be a simple differentiation or lineage cascade of mesenchymal tissue cells has proven itself to be a much more elegant and complex entity. MSCs are now known to originate as pericytes, which function as surveyors of their kingdoms, capable of responding to local environmental stimuli with a myriad of beneficial interventions.2 The availability and versatility of these remarkable cells make them an excellent treatment option for a wide variety of clinical pathologies, and it falls to the scientific community to establish clear guidelines for the optimal administration of MSC-based therapies. In the following review, we survey a brief history of MSCs, their anti-inflammatory, immunomodulatory and paracrine effects, and the current status of MSC-based therapies for a multitude of clinical applications.

Continue to read by clicking here
……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

Genzyme Receives Complete Response Letter from FDA on Lemtrada (TM) (alemtuzumab) Application



CAMBRIDGE, Mass. - December 30, 2013 - Genzyme, a Sanofi company (EURONEXT: SAN and NYSE: SNY), announced today that it has received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) for its supplemental Biologics License Application seeking approval of Lemtrada (alemtuzumab) for the treatment of relapsing forms of multiple sclerosis.
A Complete Response Letter informs companies that an application is not ready for approval. FDA has taken the position that Genzyme has not submitted evidence from adequate and well-controlled studies that demonstrate the benefits of Lemtrada outweigh its serious adverse effects. Genzyme understands that the conclusion is related to the design of the completed Phase 3 active comparator studies of Lemtrada in relapsing-remitting MS patients. FDA has also taken the position that one or more additional active comparator clinical trials of different design and execution are needed prior to the approval of Lemtrada.

Genzyme strongly disagrees with the FDA’s conclusions and plans to appeal the agency’s decision.

“We are extremely disappointed with the outcome of the review and the implications for patients in the U.S. suffering with multiple sclerosis who remain in need of alternative therapies to manage a devastating disease,” said Genzyme President and CEO, David Meeker, M.D. “We strongly believe that the clinical development program, which was designed to demonstrate how Lemtrada compares against an active comparator as opposed to placebo, provides robust evidence of efficacy and a favorable benefit-risk profile. This evidence was also the basis for the approvals of Lemtrada by other regulatory agencies around the world.”

Lemtrada is approved in the European Union, Canada, and Australia, and additional marketing applications for Lemtrada are under review by regulatory agencies around the world.

Sanofi does not anticipate that the CVR milestone of U.S. approval of Lemtrada by March 31, 2014 will be met.


About Lemtrada™ (alemtuzumab)
The Lemtrada clinical development program included two pivotal randomized Phase III studies comparing treatment with Lemtrada to Rebif® (high-dose subcutaneous interferon beta-1a) in patients with RRMS who had active disease and were either new to treatment (CARE-MS I) or who had relapsed while on prior therapy (CARE-MS II), as well as an ongoing extension study. In CARE-MS I, Lemtrada was significantly more effective than Rebif at reducing annualized relapse rates; the difference observed in slowing disability progression did not reach statistical significance. In CARE-MS II, Lemtrada was significantly more effective than interferon beta-1a at reducing annualized relapse rates, and accumulation of disability was significantly slowed in patients given Lemtrada vs. interferon beta-1a.


The most common side effects of Lemtrada are infusion associated reactions, infections (upper respiratory tract and urinary tract), lymphopenia and leukopenia. Serious autoimmune conditions can occur in patients receiving Lemtrada. A comprehensive risk management program will support early detection and management of these autoimmune events.

Alemtuzumab is a monoclonal antibody that selectively targets CD52, a protein abundant on T and B cells. Treatment with alemtuzumab results in the depletion of circulating T and B cells thought to be responsible for the damaging inflammatory process in MS. Alemtuzumab has minimal impact on other immune cells. The acute anti-inflammatory effect of alemtuzumab is immediately followed by the onset of a distinctive pattern of T and B cell repopulation that continues over time, rebalancing the immune system in a way that potentially reduces MS disease activity. Genzyme holds the worldwide rights to alemtuzumab and has primary responsibility for its development and commercialization in multiple sclerosis. Bayer HealthCare holds the right to co-promote alemtuzumab in MS in the United States. Upon commercialization, Bayer will receive contingent payments based on global sales revenue.

About Genzyme, a Sanofi Company
Genzyme has pioneered the development and delivery of transformative therapies for patients affected by rare and debilitating diseases for over 30 years. We accomplish our goals through world-class research and with the compassion and commitment of our employees. With a focus on rare diseases and multiple sclerosis, we are dedicated to making a positive impact on the lives of the patients and families we serve. That goal guides and inspires us every day. Genzyme’s portfolio of transformative therapies, which are marketed in countries around the world, represents groundbreaking and life-saving advances in medicine. As a Sanofi company, Genzyme benefits from the reach and resources of one of the world’s largest pharmaceutical companies, with a shared commitment to improving the lives of patients. Learn more at www.genzyme.com.

About Sanofi
Sanofi, an integrated global healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients’ needs. Sanofi has core strengths in the field of healthcare with seven growth platforms: diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and the new Genzyme. Sanofi is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY).
Genzyme® is a registered trademark and LemtradaTM is a trademark of Genzyme Corporation. Rebif® is a registered trademark of EMD Serono, Inc.

Sanofi Forward Looking Statements

This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance. Forward-looking statements are generally identified by the words “expects”, “anticipates”, “believes”, “intends”, “estimates”, “plans” and similar expressions. Although Sanofi’s management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include among other things, the uncertainties inherent in research and development, future clinical data and analysis, including post marketing, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug, device or biological application that may be filed for any such product candidates as well as their decisions regarding labeling and other matters that could affect the availability or commercial potential of such product candidates, the absence of guarantee that the product candidates if approved will be commercially successful, the future approval and commercial success of therapeutic alternatives, the Group’s ability to benefit from external growth opportunities, trends in exchange rates and prevailing interest rates, the impact of cost containment policies and subsequent changes thereto, the average number of shares outstanding as well as those discussed or identified in the public filings with the SEC and the AMF made by Sanofi, including those listed under “Risk Factors” and “Cautionary Statement Regarding Forward-Looking Statements” in Sanofi’s annual report on Form 20-F for the year ended December 31, 2012. Other than as required by applicable law, Sanofi does not undertake any obligation to update or revise any forward-looking information or statements.

Contacts:
Sanofi Media Relations
Jack Cox
Tel: +33 (0) 1 53 77 46 46
E-mail: mr@sanofi.com

Sanofi Investor Relations
Sébastien Martel
Tel: +33 (0) 1 53 77 45 45
E-mail: ir@sanofi.com

Genzyme Media Relations
Erin Pascal
Tel: + 1 857 248 0874
E-mail: Erin.Pascal@genzyme.com

Sanofi Investor Relations
Kristen Galfetti
Tel: +1 908 981 5560
E-mail: ir@sanofi.com

……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

Sanofi MS Drug Added With Genzyme Fails to Win FDA Approval (3)

December 30, 2013

Sanofi (SAN) failed to win U.S. regulatory approval for its multiple sclerosis drug Lemtrada, denting the company’s ambitions of capturing a larger share of the $20 billion market for the disease.
The U.S. Food and Drug Administration said Sanofi’s Genzyme unit didn’t submit evidence from “adequate and well-controlled studies” showing that the benefits of Lemtrada outweigh its side effects, the Paris-based company said in a statement today. Sanofi disagrees with the conclusion and said it will appeal.

Lemtrada, which was approved in the European Union in September, was a key part of Sanofi’s $20.1 billion acquisition of Genzyme in 2011. The FDA indicated one or more additional trials comparing Lemtrada with another drug are needed for approval, Sanofi said. 
……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

Sunday, December 29, 2013

Bad Press can lead to misconceptions

written By Rusty -                             December 29, 2013


As I sit surfing the internet and watching t.v. hoping for any new information on treatment or a cure for multiple sclerosis, I come across a few web sites claiming they have discovered the answers to help and reverse the horrendous effects of MS. Why has no on e else found this fountain of youth?

Here are a few of those web sites.





(All with money back guarantees Just send them your credit card number first)..
>>> No, I am NOT suggesting you contact any of these - Continue reading please<<<


Should the drug companies be worried that they are trying to muscle in on their cash flow? Are they just selling the IDEA of a possible cure.. key word being "possible".

With the FDA so opinionated on stem cell usage, its hard to believe they don't use the same rational for judgment. Why doesn't the FDA use the same logic on organ transplants.

Why don't these companies offer these programs at no charge to start with, and payment only if it works, like it reports too. What are they worried about?

Are these just fast talking wannabe rich people trying to sell some unproven elixir or process with no proven or tested results.

I have sent each of these sites the offer of myself ( an MS sufferer ) to test their solution with double the payment if their solution works for me., along with an example of success for their product. It worked well for the Subway sandwich chain and Jarrod..


Why wouldn't they do it?  

Comment please




special amendment: Stuart just read this article: http://www.newsday.com/business/press-releases/multiple-sclerosis-natural-treatment-review-exposes-fastest-way-to-stop-ms-symptoms-1.6688998    and thinks that the Newspaper did wrong in Justifying this information.

what do you think?








……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

Saturday, December 28, 2013

Reducing Stress Part II: Get Out Of Your Head, Create A Scrapbook -

by Laurie Erdman



The greatest source of stress in our lives is work. But unless you win the lottery (I hear you have to play to win), work is inevitable. That means stress is inevitable.

I heard it said that no one dies of a snakebite. They die of the venom. The same could be said of stress. No one dies of stress, but they die from their reaction to stressful events.

Last week I introduced you to step one of my three-step formula for relieving stress naturally. I hope you dove right in and started implementing. This week, I’m sharing the final steps in the formula.

Step Two: De-Stress Your Mind

When I ask audiences the question, “What is stress?” I typically receive answers such as “deadlines,” “traffic,” “over-commitment,” “not enough time,” and even “having to deal with “stupid” people.” These answers suggest that many of us believe stress is something that happens to us. In reality, stress is merely our response to all those external factors.
The stress response is a function of our autonomic nervous system’s flight-or-fight response. Specifically, stress is triggered by a thought or belief that we are in danger — our body then goes into overdrive producing cortisol and adrenaline to help us get out of danger as fast as possible.

In modern life, we spend far more time engaging this stress response than we do engaging our relaxation response. This has serious consequences for our health, as too much stress can accelerate the aging processsuppress our immune systems and leave us feeling fatigued and depressed

The key takeaway here is that stress begins in our minds via a thought or belief. Thus, it’s important to neutralize stress by fueling our minds with more positive, happy, gratitude-filled thoughts in order to trigger our stress responses less often.

Stress-Relieving Tips for your Mind

  1. Cultivate gratitude. We are going to have things go wrong in our day. It’s inevitable. We can take the sting out of these negative events by focusing on what’s great in our life. A gratitude practice will help you focus. Each evening, write down three things you are grateful for. They can be as simple as seeing a gorgeous sunrise to being complimented on your new shoes.
  2. Meditate regularly. A consistent meditation practice — even if it’s only five minutes a day — may help lower blood pressure, and can help us control the thoughts that can trigger stress. The next time you get stressed because your boss just added another task to your already overflowing to do list, stop and take a breath. Shake out your body, sit back down and meditate for 5 minutes.
  3. Learn to say no. Being overbooked, worked and committed will lead to stress. We often feel obligated to say yes to everything for fear we won’t be liked. The greatest act of stress relief is exercising your right to say no. You can explain to others that you are overcommitted and you just must say no. And yes, you can even tell your boss no, just explain that one more project will mean the quality of your work will drop. Negotiate priorities.

Step-Three: Don’t Lose Sight of Your Purpose

Each of us is more than the work we do. We are creative, in relationships, spiritual beings, and passionate. Connecting with our whole selves by fueling our sense of purpose is the keystone for less stress and more happiness.

“What’s that?” you say? What is purpose and what does it have to do with stress? As I’ve written before, purpose can be thought of as a person’s calling in the world — but it’s really broader than that. It encompasses everything from meaningful work to relationships to the hobbies that brings us joy and meaning. Purpose is the expression of our own unique spirit.

When we starve our purpose — by not engaging with our work, suppressing our creativity, or ignoring our relationships (including the one with ourselves) — we trigger our stress response. When our life is full of nothing but work and obligations, we begin to get bitter, resentful, depressed, and even angry. Fueling all facets of our life is the antidote and gives us even more for which we can be grateful.

Stress-Relieving Tips for Your Purpose

  1. Re-attach to your relationships. When we’re working crazy hours, we can find ourselves detached from our relationships. Each week, schedule some time with a loved to just be together, hang out, and laugh. No work talk allowed, and no checking the Smartphone. Disengage from work and reengage with those that matter.
  2. Get creative. Remember how much fun you had as a kid doing crafts. You might have stopped because your last creation wasn’t perfect. Or you didn’t have the time. Carve out some time to be creative and tap into your inner kid. Creativity can be cooking dinner, handwriting a card to a friend or creating a vision board. Get out the scissor and glue stick and just play.
  3. Get spiritual. It’s human nature to seek connection to a higher power, however that may look for you. There’s even evidence that we are hard-wired for spirituality. Yet when we are overworked and chronically stressed we can forget about our place in the bigger picture. Connecting with your spiritual roots through prayer, meditation, chanting or other forms of spiritual ritual is an excellent way to get perspective on what’s stressing you and relieve that pressure.
  4. Managing Workplace Stress: The Takeaway

We cannot eliminate or escape stress at the workplace. It is a fact of modern life. Yet we can neutralize stress in all areas of our lives by fueling our lives with meaningful actions, thoughts, and beliefs. We all deserve to live a happy, contented life. It’s never too late to start making yours.

How will you relieve stress today? Let me know in the comments below.

- See more at: http://www.theignitewellbeinginstitute.com/reducing-stress-part-ii-head-create-scrapbook-pray/#!


Laurie Erdman, JD, MS, CHHC is a speaker, Get More Energy Strategist and the CEO of The Ignite Well Being Institute LLC where she helps companies sustain fast growth by energizing their people. 


To download her FREE book: Burnout. Identify It. Extinguish It. Ignite Your Life visit www.TheIgniteWellBeingInstitute.com. - 





……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

With 2013 coming to a close, please read...


DEAR ALL - 

Thank you for following what we do, to provide information, education and resources to those affected by Multiple Sclerosis. Many hours go into the development of our education programs, the planning, the day of activities and then the reconciliation of each meeting. 

This year, we began video-recording our programs so that we could archive these as an enduring material making our programs available for anybody with internet access to watch and to learn.

The hours, the time, the video recordings, and many of the programs all take money..  Occasionally we do programs even without grant dollars to do them. 

Private contributions were lower this year than previous years. Sure the economy is still strapping for many. I understand this.

However, I also know that the end of the year is soon upon us and many of you will be making your last minute end of year contributions for tax deductions.

MS Views and News is a 501c3 Not for profit organization. Your contributions to us are tax deductible to the fullest extent allowed by law.

Multiple Sclerosis can effect anybody at anytime. There are no age limits nor religious or ethnic boundaries. There are no fences or borders. 

MS Views and News helps to erect confidence by addressing the need for people to learn about the disease, the medications, symptom management and a variety of other topics relating to Multiple Sclerosis

Consider Your dollars in helping us to help the educate the MS community. Consider MS Views and News for this end of year contribution.

Please Click www.donations.msviewsandnews.org  and donate.
No amount is too small. Help us to help others. 
Donate, Please


Thank You and have a Happy New Year 

Stuart Schlossman 
President and an MS Patient
MS Views and News


















……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

Friday, December 27, 2013

Help Prevent Flare-Ups

Call it a flare-up, an exacerbation, an attack, or a relapse. Whatever you call it, it's not something you expect. When you have relapsing-remitting multiple sclerosis (MS), you can go days or years without major changes in your symptoms. Then, suddenly, things change.
You'll work closely with your doctor to feel better. You can also reset your schedule to take special care of yourself. Exercise, stretching, and relaxation can help you manage MS symptoms -- and they boost your mood, too.

Symptoms of a True Flare

Here's how to tell if you're having a relapse of MS, when the illness is active again:
  • You develop a new symptom of MS. For example, you’ve never had vision problems before, and suddenly you can’t see clearly out of your left eye.
  • A regular problem gets worse. Maybe you’ve had some numbness in your left leg before, but now you can’t feel anything below your knee.
  • Your symptoms last for 24 hours or longer. A relapse means a change in your brain, called a lesion. "If a symptom lasts less than 24 hours, it’s something transient that’s not related to a new lesion," says Edward Fox, MD, PhD, director of the MS Clinic of Central Texas.
  • Symptoms level off after a while and stop getting worse.
MS flares can last days, weeks, or even as long as a year.
"Then they usually do improve, but recovery can be quite slow," says Bruce Cohen, MD, of the Northwestern University Feinberg School of Medicine. You may recover completely, or you could have some permanent loss of function or sensation.


……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

MS breakthrough: London researchers have fine-tuned a high-powered MRI to actually measure the amount of damage to that protective sheath

HEALTH RESEARCH

MS breakthrough for Western team



By Jonathan Sher, The London Free Press
London scientists have made a breakthrough fighting the scourge of multiple sclerosis, fine-tuning MRIs to detect the disease before it ravages its victims.
“This could be a real game-changer,” said Dr. Bruce Bebo, who this year will decide how to invest $50 million in research raised by the National MS Society in the United States.
Bebo marvelled Thursday from afar at the work of a London research team headed by Dr. Ravi Menon that’s aimed at what has been an elusive target — finding and treating MS before it causes physical and cognitive ­impairment.
The challenge is especially pressing in Canada, where MS rates are the highest in the world — nine times higher than the world average.
Neurologists have long used MRIs to diagnose MS by showing damage to the protective sheath that insulates the body’s central nervous system.
Now, London researchers have fine-tuned a high-powered MRI to actually measure the amount of damage to that protective sheath —called myelin — as well as the deposits of iron typically found with the disease.
The team from Western ­University perfected the scans first on rats in a study published this month in the journal Proceedings of the National Academy of Sciences.
“It’s a huge step (forward),” Menon told The Free Press.
They then tested it on ­people, and though that study won’t be published until January, ­preliminary data showed that damage might be pinpointed
long before patients are ­traditionally diagnosed, potentially before they had suffered any ill effects.
“It’s really the holy grail, being able to track myelin,” Bebo said.
Though it’s not practical or affordable to screen everyone for MS using an MRI, research is underway to identify those most at risk from the disease. Some day, that work might lead to simpler tests such as a blood test to find those more at-risk who could then be scanned before the onset of symptoms, Bebo said.
In the meantime, more precise MRIs may help people already being treated for the disease with conventional drugs that suppress their immune system — it’s the immune system that attacks the myelin.
That treatment is by trial and error: If patients continue to deteriorate, doctors switch medications. Menon’s MRIs might help doctors switch away from failing medications before the damage occurs, Bebo said.
New research is aimed at reversing the damage to myelin, a task that may deliver even greater benefit if MS is discovered early, he said.
News of the breakthrough brought optimism this week to a Londoner who has grown skeptical over 30 years about “breakthroughs” as he helped his wife and the local MS society.
“It’s been a slow grind to hell,” Bob Sadler said of the challenges faced by his wife Margo and others with the disease. “An early detection system would be great.”
Menon’s team is not the only one seeking a more precise way to find MS and track its course. American researchers at Case Western Reserve University School of Medicine this month published research using a different type of scanner aimed not at the brain but the spinal cord, using gamma rays in what’s commonly called a PET scanner.
Source: lfpress.com


……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.

a FREE WiFi "WARNING" -- Not MS related

Not MS related But Truly IMPORTANT to Know

I obtained this from the State of Florida


Print this from your browserView PDF Online
Free Wi-Fi May Cost Your Your Identity

These days, everyone is on-the-go. As a result, free Wi-Fi is now offered in many public places such as hotels, airports and coffee shops. This has made it easier than ever to stay connected while you travel, but not without risk. Most individuals don’t think twice about accessing an open network, even to make a purchase or check a bank balance. However looks can be deceiving and not all Wi-Fi hotspots are legitimate. Fraudulent individuals can set up a real Wi-Fi hotspot in a public area such as a café, with the sole purpose of stealing personal information.
How It Works

Fraudsters set up ad-hoc networks or computer-to-computer networks from a laptop in public areas, particularly airports, to gain access to others’ personal devices. They use labels like "Free Wi-Fi" or "Wireless Connection" to appear legitimate. When using your personal computer or smart phone in a public area, you may choose to connect to the network, not knowing it is not legitimate, or your device may automatically connect. Once the connection is established, a fraudster can see everything you browse online, including personal or financial information. Furthermore, if your computer allows file sharing, attackers can access personal files and data on your computer and may even install malicious software.

Protect Yourself The easiest way to protect yourself from Wi-Fi fraud is to avoid connecting your personal device to any free wireless networks. If you decide to use a free Wi-Fi connection, here are some useful tips to keep in mind:
  • Beware of Evil-twin hot spots. Scammers will sometimes set up a Wi-Fi hotspot near a business that already provides Wi-Fi to its customers. They may even use the same Wi-Fi name as the legitimate internet connection offered by the business in order to lure victims into connecting to their network. If you see two hot spots with the same name, make sure you check the network description of each one. A normal wireless network will simply say "wireless network" - make sure to avoid any networks that say "computer-to-computer" network.

  • Disable automatic connections. Make sure that your computer has not been configured to automatically connect to any wireless networks within your range. Otherwise, your computer may automatically connect to a bogus Wi-Fi network.

  • Set up a Virtual Private Network (VPN). If you regularly access online accounts through Wi-Fi hotspots, use a virtual private network. VPNs encrypt traffic between your computer and the internet, even on unsecured networks. You can obtain a personal VPN account from a VPN service provider. In addition, some organizations create VPNs to provide secure, remote access for their employees.

Source: 
For additional information, contact the Florida Department of Agriculture and Consumer Services at www.800helpfla.com or call 1-800-HELP-FLA (435-7352) within Florida, (850) 410-3800 from outside of Florida or 1-800-FL-AYUDA (352-9832) en Español.




……..


To comment - click the comment link shown below
…….
Share our Articles with others
……
REMAIN CURRENT with MS News and and Information
Register at:  www.msviewsandnews.org  
-------------
YOUR HELP WILL Help us to Educate those affected by Multiple Sclerosis
Donations are Tax Deductible to the Fullest extent allowed by Law
Donate Now Please - Click here
Thank you
…………………….
.