A web-blog (formerly known as Stu's Views and MS News), now published by MS Views and News, a patient advocacy organization. The information on this blog helps to Empower those affected by Multiple Sclerosis globally, with education, information, news and community resources.
~~ Scroll left side of this blog for needed resources. Also, use our 'search by topic' tool, to find specific information.
Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
Wednesday, October 9, 2013
New technique for imaging myelin loss and repair shows potential for identifying compounds with future potential to treat MS
Oct 03, 2013
Researchers in Cleveland and London, funded by the National MS Society have achieved a new way to visualize and monitor the loss and repair of nerve-insulating myelin over time, creating a non-invasive tool to identify compounds with future potential to treat MS. Their studies used PET (positron emission tomography) imaging in rats as a non-invasive way to detect myelin damage and its subsequent repair by an experimental compound. Yanming Wang, PhD, Chunying Wu, PhD, Robert Miller, PhD, and colleagues at Case Western Reserve University and Imperial College, London, recently reported results in the Annals of Neurology.
Background: In multiple sclerosis, myelin, the fatty substance that surrounds and protects nerve fibers, is attacked and destroyed, leading to many possible neurological symptoms. Several therapies currently under development aim at promoting myelin repair, but there is no established means of observing myelin repair over time in a non-invasive manner. MRI scans are commonly used to image disease activity in the brain, but MRI is not sensitive enough to reveal specific information about myelin damage or repair. Thus, a new imaging technique is crucial for assessing how well new therapies aimed at myelin repair work.