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Thursday, September 4, 2014

Biogen Idec Data at Joint ACTRIMS-ECTRIMS Meeting Highlight Robust Multiple Sclerosis Portfolio and Commitment to Advancing Patient Care

- Data Further Support Industry-Leading Portfolio of MS Treatments and Innovative Pipeline Therapies -
- Innovative Programs Reinforce Commitment to Improving the Lives of People Living with MS -

CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Biogen Idec (NASDAQ: BIIB) will present more than 90 company-sponsored platform and poster presentations on data supporting its marketed and investigational therapies for multiple sclerosis (MS), as well as the company’s programs to address unmet needs in patient management, at the sixth Triennial Joint Meeting of ACTRIMS and ECTRIMS in Boston, September 10 – 13, 2014. The breadth and volume of data exemplify Biogen Idec’s industry-leading expertise in research and development, comprehensive product portfolio, and enduring commitment to the MS community. ACTRIMS-ECTRIMS is the joint meeting of the Americas Committee for Treatment and Research in Multiple Sclerosis and the European Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS-ECTRIMS).

“We are dedicated to advancing MS care through innovative clinical research on promising CNS targets with the potential for treating this disease and through novel initiatives that address critical disease management issues,” said Douglas E. Williams, Ph.D., executive vice president, Research and Development at Biogen Idec. “This includes our collaboration with the MS community to better understand the patient experience to help patients and physicians better work together to manage the disease.”

Biogen Idec data to be presented at ACTRIMS-ECTRIMS include results from studies of its currently approved products, TECFIDERA® [delayed-release dimethyl fumarate (DMF; also known as gastro-resistant DMF)], TYSABRI® (natalizumab), FAMPYRA® (prolonged-release fampridine tablets) and PLEGRIDY™ (peginterferon beta-1a), as well as findings from the clinical programs of its MS pipeline candidates, ZINBRYTA™ [daclizumab high-yield process (DAC HYP)] and Anti-LINGO-1 (BIIB033).

Biogen Idec will also present information on several of the company’s initiatives that seek novel solutions to improve MS patient management, reinforcing the company’s commitment to comprehensively meet the needs of people with MS. These include highlights from the Value-Based Medicine (VBM) group, focused on developing and deploying new technology to help enhance individualized treatment decisions and a consensus opinion study of U.S. neurologists to assess practice patterns in the management of MS, and to inform U.S. consensus guidelines for treatment initiation. Additionally, highlights from an international survey of patients and neurologists designed to understand the current “State of MS,” including the quality of communication between MS patients and their physicians, will be presented.

Biogen Idec will also host a journalist and advocacy group briefing about the “State of MS” survey findings on Wednesday, September 10 at 11:30 a.m. – 1 p.m. EST. The discussion will focus on the relationship and communication between neurologists and people living with MS.

Highlights of Biogen Idec’s ACTRIMS-ECTRIMS Data

  • Consensus Opinion of U.S. Neurologists on Practice Patterns in Radiologically and Clinically Isolated Syndrome and Relapsing-Remitting MS – Poster #295 – Thursday, September 11, 2014 – 3:30-5:00 PM
  • The State of MS: Current Insight Into Patient-Neurologist Relationships, Barriers to Communication, and Treatment Satisfaction– Poster P824 – Friday, September 12, 2014 – 2:45-4:15 PM
  • Value Based Medicine: Enabling Evidence-Based and Individualized Treatment Decisions for Patients With Multiple Sclerosis – Poster P825 – Friday, September 12, 2014 – 2:45-4:15 PM

  • Five-Year Follow-up of Delayed-Release Dimethyl Fumarate in RRMS: Integrated Clinical Efficacy Data from the DEFINE, CONFIRM, and ENDORSE Studies – Poster P110 – Thursday, September 11, 2014 – 3:30-5:30 PM
  • Long-term Follow-up of the Effect of Delayed-Release Dimethyl Fumarate on No Evident Disease Activity in Patients with Multiple Sclerosis – Platform FC3.5 – Friday, September 12, 2014 – 9:03 AM

  • Correlations Between Patient-reported Ambulatory Function (MSWS-12) and Objective Disability Measurements in SPMS: Analysis of ASCEND Baseline Data – Poster P777 – Friday, September 12 – 2:45 – 4:15 PM

  • Effect of Peginterferon Beta-1a on MRI Measures and Freedom From Measured Disease Activity: 2-year Results From the Phase 3 ADVANCE Study – Poster P067 – Thursday, September 11, 2014 – 3:30-5:00 PM
  • Clinical Efficacy of Peginterferon Beta-1a in Relapsing-Remitting Multiple Sclerosis: 2-year Data From the Phase 3 ADVANCE Study – Platform FC2.5– Friday, September 12, 2014 – 9:03 AM

  • Psychometric Testing of the Early Mobility Impairment Questionnaire for Multiple Sclerosis – Poster P784 – Friday, September 12, 2014 – 2:45-4:15 PM
  • Walking Ability and Balance in Patients with Multiple Sclerosis Treated with Prolonged-Release Fampridine: Randomized, Double-Blind MOBILE Study – Poster P922 – Friday, September 12, 2014 – 2:45-4:15 PM

  • Safety and Tolerability of Daclizumab HYP Treatment in Relapsing-Remitting Multiple Sclerosis: Results of the DECIDE Study – Poster P094 – Thursday, September 11, 2014 – 3:30-5:30 PM

  • Primary Results of DECIDE: A Randomized, Double-Blind, Double-Dummy, Active-Controlled Trial of Daclizumab HYP vs. Interferon Β-1a in RRMS Patients – Platform FC1.1 – Friday, September 12, 2014 – 8:15 AM

Anti-LINGO -1
  • A Phase II Study of the Anti-LINGO-1 Monoclonal Antibody, BIIB033, in Subjects With Acute Optic Neuritis: Baseline Data – Poster P731 – Friday, September 12, 2014 – 2:45-4:15 PM
Full session details and data presentation listings for the 2014 Joint ACTRIMS-ECTRIMS Meeting can be found at the meeting website,

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