Please visit our MS learning channel on Youtube, which provides hundreds of topics from our education programs, that were video-recorded and archived here: www.youtube.com/msviewsandnews

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Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

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CHAMPIONS TACKLING MS - AWARDS Dinner, Honoring Aaron Boster, MD and Jon e. Glaser, DDS - now open for registration. Visit www.events.msvn.org

Saturday, March 15, 2014

THE BRAND YOU KNOW AND TRUST - NOW AVAILABLE IN A 3-TIMES-A-WEEK DOSE

Stu's Views - Remaining with a proven medication sure beats a generic substitution, where you really do not know what might be in the formula.

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Introducing 3-times-a-week COPAXONE® 40 mg
Experience treatment on your terms with 3-times-a-week COPAXONE® 40 mg.
NEW 3-times-a-week COPAXONE® (glatiramer acetate injection) 40 mg is an injectable therapy, indicated for the treatment of people with relapsing forms of multiple sclerosis. With 3-times a week COPAXONE®40 mg, you can feel confident that your therapy offers
  • Proven effectiveness1
  • Demonstrated safety and tolerability profile1
  • The #1 prescribed brand for relapsing MS in the US2*
  • The Shared Solutions® network of personalized support
Your co-pay for 3-times-a-week COPAXONE® 40 mg could be lowered to $0 per month out of pocket.††
Take control of your relapsing MS now. Call Shared Solutions® today at 1-800-887-8100. See why so many in the relapsing MS community have put their trust in COPAXONE®, and experience the future with new 3-times-a-week COPAXONE® 40 mg.

Want to find out more about NEW 3-times-a-week COPAXONE® 40 mg from a leading MS expert?  CALL AN MS-CERTIFIED NURSE - 1.800.887.8100

Get started today.
Get started today.
Call Shared Solutions® at 1-800-887-8100



TAKE CONTROL WITH PROVEN EFFECTIVENESS

Since the approval of COPAXONE® (glatiramer acetate injection) for relapsing‐remitting MS in 1996, many in the MS community have trusted in its proven effectiveness across 5 large clinical studies. Most recently, 3-times-a-week COPAXONE® 40 mg was studied in the largest pivotal trial ever conducted for COPAXONE®.1




3-times-a-week COPAXONE® 40 mg: Proven to reduce the number of relapses

3-times-a-week COPAXONE® 40 mg reduced the number of relapses by 34% compared to placebo (an inactive substance).


Primary study results

Relapses, also called flare-ups or attacks, can cause new symptoms to occur or make old symptoms worse.
34
Fewer relapses
compared with
placebo1

3-times-a-week COPAXONE® 40 mg: Proven to reduce the number of brain lesions1

COPAXONE® 3-times-a-week 40 mg showed a significant cumulative reduction in the underlying disease activity as measured by brain lesions on magnetic resonance imaging (MRI) at 6 and 12 months compared to placebo.


Secondary study results

T2 lesions show areas where the brain tissue has been damaged.
35
Reduction in
the total
number of new
and enlarging
T2 lesions


Secondary study results

T1-enhancing lesions, also known as Gadolinium-enhancing T1 lesions, show areas where brain tissue is currently being attacked.
45
Reduction in
the local number
of enhancing
lesions on
T1-weighted
images
Expand Study Details


Take control now. Call Shared Solutions® today at 1-800-887-8100 to find out how you can get started on 3-times-a-week COPAXONE® 40 mg.



STAY THE COURSE WITH A THERAPY YOU TRUST

3-times-a-week COPAXONE® 40 mg offers you a demonstrated safety profile.1 With 3-times-a-week COPAXONE® 40 mg, you can feel confident in your decision to stay committed to your relapsing MS therapy.
Drug Interactions

Although not fully studied, COPAXONE® has not demonstrated any significant interactions with medications commonly used in MS patients.
This includes combination use with corticosteroids (up to 28 days)
COPAXONE® has not been formally evaluated in combination with interferon beta
COPAXONE® is Pregnancy Category B

There is no evidence of risk in humans.

Animal studies have failed to demonstrate a risk to the fetus, and there are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, COPAXONE® should be used in pregnancy only if clearly needed.

If you are pregnant or planning to become pregnant, let your doctor know.

Continue reading, HERE

Call Shared Solutions® today at 1-800-887-8100 to find out how you can feel confident with 3-times-a-week COPAXONE® 40 mg.

STAY THE COURSE WITH A THERAPY THAT FITS YOUR LIFESTYLE


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Friday, March 14, 2014

MS Symptoms and Types of Multiple Sclerosis

Symptoms & Types

For every person, the disease develops differently. Yet the early warning signs are quite similar. Learn the symptoms, the types of MS, and possible complications.

Symptoms

It’s important to recognize the early symptoms of MS.
Take WebMD’s MS Health Check to see how you’re handling your health and well-being and test your knowledge about multiple sclerosis.
Tremors are recognizable symptoms of MS. Here’s what you should know.
Fatigue is a big problem if you have MS. Conserve your personal energy with these tips.

Warning Signs

Certain warning signs might mean MS -- or they could signal another disease, like stroke.
Vision problems can be the first symptoms of MS. Learn more about these first signs.
Thinking and memory problems are often early signs of MS. Learn more about these symptoms.

Types

Read about Types of MS by clicking here





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Multiple Sclerosis and Exercise

Exercise can help ease the symptoms of multiple sclerosis, but it's important to take certain precautions if you want your exercise program to be successful. The most important thing to remember is to not overdo it.
You may have heard the sayings "no pain, no gain" or "feel the burn," but those approaches are not helpful for people with MS. If you overdo it, you can end up straining an already taxed muscular system, increasing pain and causing your body and mind to become overstressed, overworked, and overtired.
Check with your doctor before beginning any exercise program. He may make recommendations about:
  • The types of exercise best suited to you and those you should avoid
  • The intensity of the workout (how hard you should work)
  • The length of your workout and any physical limitations
  • Referrals to other professionals, such as a physical therapist, who can help create a personal exercise program that meets your needs. The type of exercise that works best for you depends on your symptoms, fitness level, and overall health.

Tips for Safe Exercise With Multiple Sclerosis

  • Always warm up before beginning your exercise routine and cool down at the end.
  • If you plan to work out for 30 minutes, start with 10-minute workout sessions and work your way up.
  • Work out in a safe place; avoid slippery floors, poor lighting, throw rugs, and other potential tripping hazards.
  • If you have trouble balancing, exercise within reach of a grab-bar or rail.
  • If at any time you feel sick or you begin to hurt, STOP.
  • Select an activity that you enjoy and have fun. Water aerobics, swimming, tai chi, and yoga are examples of exercises that often work well for people with MS.

What Should I Do if I Get Overheated?

Some people with MS are sensitive to heat, which means they notice that their symptoms either reappear or become worse when their body heat rises. This will happen when you exercise. Here are some tips to avoid overheating.
  • Don't exercise during the hot time of the day (10 a.m. to 2 p.m.). Try to exercise in the morning or evening if you are exercising outside.
  • Drink plenty of cool fluids.
  • Become aware of your body. If you notice any symptoms that you didn't have before you began exercising, slow down or stop exercising until you cool down.
  • Swimming and water aerobics are good ways to stay cool while you exercise. Also, make sure that there are non-slip floors in the locker room and around the pool.

Source: Webmd


WATCH videos of Adaptive Exercise for MS by visiting our Video archives found here: www.youtube.com/msviewsandnews 


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Thursday, March 13, 2014

Lemtrada: New Multiple Sclerosis drug on the market for Canadian patients








Lemtrada is a new multiple sclerosis drug now on the market for Canadians


By Oona Woods

There is a new drug on the market for Canadians who have the most common form of Multiple Sclerosis. Lemtrada has been approved for use after a University of Ottawa-based team conducted clinical trials over the last four years.

The drug kills white blood cells which stops them from entering the brain and attacking it.
Lemtrada has been given the green light both here and in Europe but not America. It was previously marketed for Leukemia sufferers under the name Campath.

Ottawa MS patient Kelly Lauzon was diagnosed with MS in 2000. For the following decade she had recurring relapses of the disease.

“Prior to being on this drug I was relapsing every 12 months,” she said.
“For me, I was always affected by my vision, I would basically go blind. This means I can’t drive, I was counting steps in my own home.”

Lauzon says she has not had a single relapse since being on Lemtrada. She has also noticed an improvement in her ability to sleep through the night.

“After one month of this trial I woke up literally in tears saying to my boyfriend, ‘is this how normal people sleep?’ It had been so long I forgot,” she said.

Trials of the drug resulted in one death in the past, but doctors say they are administering it intravenously and that avoids double contact with the liver, which caused problems. Side effects can affect the thyroid along with milder ailments like fevers, rashes and nausea.
Dr Mark Freedman is a Neurologist and Professor of Medicine with the University of Ottawa. He says the drug is a highly effective therapy that can be injected once a year and then not maintained.


Before reading more of this article  - Know that the FDA recently declined the use of this medication in the USA. Please read a petition about this and sign so that we can get the FDA to see that Patients want a new choice.
Click here to review this petition


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Wednesday, March 12, 2014

MS community shocked by FDA's rejection of drug

March 08, 2014 11:00 pm  •  

Harold Johnson was going downhill fast. The medication he injected three times a week for his multiple sclerosis was making him feel like a zombie, and it wasn’t helping. His vision was getting worse, and he would choke when eating or drinking, and would shake and stumble.
“The day that bothered me the most was when I went to my mom and dad’s house on Mother’s Day. I had to use a cane to walk in front of my mom,” said Johnson, 43, of Swansea. “That affected me.”
Things dramatically changed about four years ago, after Johnson began taking part in a study of the experimental drug Lemtrada.
The canes and walker he sometimes used are collecting dust in his hallway. He can ride his bike, play in the park with his dog, build robots in his basement and work full time as a computer technician at Southwestern Illinois College. Imaging of his brain shows no new damage.
“Within three weeks, I felt like Superman,” Johnson said. He even got married.
Many with the debilitating neurological disease have stories like Johnson’s. A study of nearly 1,400 patients with progressive forms of multiple sclerosis showed those taking Lemtrada had nearly 50 percent fewer new attacks than those taking the current best medication. New brain lesions were also significantly reduced. The findings have already led Canada, Australia, Mexico and the European Union to approve the drug for treatment of multiple sclerosis.
However, in late December, the U.S. Food and Drug Administration ruled the drug was not ready for approval, surprising and disappointing doctors, patients and advocates.
“The data was highly impressive to neurologists involved in treating MS,” said Dr. Barry Singer, director of the MS Center for Innovations in Care at Missouri Baptist Hospital and who is involved in the clinical studies of the drug. “It frankly came as a shock that the medication did not get approved.”
Multiple sclerosis is an unpredictable and disabling disease where the immune system attacks the central nervous system. Symptoms range from numbness and tingling to blindness and paralysis. About 2.3 million people worldwide have MS, including 400,000 in the U.S.
FUTURE OF THERAPIES
Medical professionals are worried that the decision not only reduces much-needed treatment options but could have ramifications for future MS research. Doctors and nurses recently joined forces with advocates to send a letter to the FDA outlining their concerns.
“We’re trying through advocacy to have a fresh review of the results and a potential reversal of the decision,” Singer said.
The drugmaker, Genzyme, is appealing the ruling; and patients, friends and family members are urging citizens to sign an online petition asking the FDA to reverse its decision.
AFTER SIGNING the online petition, please continue reading this article, by clicking here



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Cuprizone-induced demyelination as a tool to study remyelination and axonal protection

Abstract

In the brain of multiple sclerosis (MS) patients, the conduction block of axons due to demyelination and inflammation underlies early neurological symptoms, whereas axonal transection accounts for permanent deficits occurring during later disease stages. The beneficial function of myelin for the protection of the axonal compartment and network stability between neurons has been shown in numerous studies. Thus, rapid and adequate remyelination is an important factor for axonal patronage during neuroinflammatory conditions. In this review article, we discuss frequently used experimental in vivo and in vitro animal models to examine remyelination and repair in MS. The focus of the discussion is the relevance of the toxin model 'cuprizone' to study the pathology of demyelination and the physiology of remyelination. This also includes recent findings in this animal model which implicate that axonal damage is an ongoing process independent of the initiation of endogenous remyelination.
PMID:
 
23666824
 
[PubMed - in process]   

http://www.ncbi.nlm.nih.gov/pubmed/23666824


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Demyelination and remyelination in anatomically distinct regions of the corpus callosum following cuprizone intoxication.

Abstract

Multiple sclerosis is a chronic demyelinating disease of the central nervous system. Spontaneous remyelination during early disease stages is thought to preserve and partially restore function. However, this process ceases in later stages despite the presence of pre-oligodendrocytes. Cuprizone-induced demyelination is a useful model with which to study the remyelination process. Previous studies have demonstrated heterogeneities in demyelination in individual animals. Here we investigated regional differences in demyelination and remyelination within the corpus callosum. C57BL/6 mice were fed 0.2% cuprizone for 5 weeks to induce demyelination. Remyelination was examined 2-5 weeks after cuprizone withdrawal. Immunohistochemistry and electron microscopy were used to quantify regional differences in demyelination, gliosis, and remyelination. We found that, while demyelination was limited in the rostral region of corpus callosum, nearly complete demyelination occurred in the caudal callosum, beginning at approximately -0.5mm from bregma. Astrogliosis and microgliosis were correlated with demyelination and differed between the rostral and caudal callosal structures. Remyelination upon cessation of cuprizone ensued at different rates with splenium remyelinating faster than dorsal hippocampal commissure. Our data show anatomical differences of cuprizone-induced demyelination and remyelination in the corpus callosum and the importance of examining specific callosal regions in myelin repair studies using this model.
Copyright © 2011 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.


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MSVN wants to develop ourselves across the USA

MS Views and News, a 501c3 Not for Profit, seeks an injection of Philanthropic dollars to help us to grow nationally as our unique style of MS education programs are needed throughout the USA so that people affected by Multiple Sclerosis can properly learn from a wide-scope of medications and treatments available. For more information contact Stuart Schlossman - at : stuart@msviewsandnews.org  - Your Help will enable us to make a difference in the lives of those affected by this Chronic Disabling disease.

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Tuesday, March 11, 2014

Scientists one step closer to treating multiple sclerosis

Multiple sclerosis attacks nerves

Multiple sclerosis attacks nerves


The recent discovery of a new type of blood cell may lead to strides in the treatment of multiple sclerosis, an autoimmune disease that currently affects approximately 2.3 million people worldwide.

The Biotech Research and Innovation Centre at the University of Copenhagen in Denmark announced the discovery of a new type of regulatory white blood cell in a study published Feb. 16 in the journal Nature Medicine. The cell has proven successful in combating the inflammatory T-cells in mice that induce the type of brain degeneration seen in diseases like multiple sclerosis.

In neurodegenerative diseases like MS, patients lose myelin, the insulation protecting neurons in the brain and spinal cord, because of inflammation caused by runaway T-cells.

The substance produced by the newly recognized cells, FoxA1, may counteract the nerve-damaging inflammation. The new cell is more abundant in patients treated with interferon, naturally occurring proteins that can help boost immune function, according to Dr. Anthony Reder, professor of neurology at the University of Chicago.



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Medical marijuana for multiple sclerosis: Portland symposium planned

medmarijuana.JPG
Some with multiple sclerosis benefit from using medical marijuana. (Beth Nakamura/The Oregoniat
Katy Muldoon | kmuldoon@oregonian.comBy Katy Muldoon | kmuldoon@oregonian.com 
 on March 10, 2014 at 6:00 AM

A symposium designed to educate patients with multiple sclerosis on use of medical marijuana, Oregon law and how patients can be safe, legal participants in the state's medical marijuana program is planned from 2 to 5 p.m. Sunday, April 6, at the Roseland Theater, 8 N.W. Sixth Ave.



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One-on-one peer connections

MS affects everyone differently- that’s why it is important to have someone you can count on to support you in the way that you need.

Through the Peer Connections program you can search for and connect with a peer support volunteer who has “been there” and can provide you with helpful tips, suggestions and emotional support for the challenges that MS throws at you.  You can connect with your peer via one-on-one ongoing telephone or email conversations.  Peer Connections volunteers have been through a rigorous screening and training process.

What are the benefits of a Peer Connections relationship?
  • Pick your own peer from a list of trained peer support volunteers from many different walks of life, including family members of those living with MS.
  • Connect with your peer via email or telephone.
  • Have confidential conversations with the same person about the topics most relevant to your life.
Search for a peer by clicking here

MSFriends

MS knows no timetable – this is why we offer support when you want and need it.

The MSFriends program connects you with volunteers living with MS. The common bond of living with MS creates a unique connection. MSFriends volunteers complete a rigorous screening and training program and are focused on the needs of those who call for support.

What are the benefits of an MSFriends peer relationship?
  • Having someone who knows first-hand what it is like to live with MS to talk with and share your story. MSFriends is there to help you deal with the changes brought about by MS.
  • Having a sounding board for good decision-making and problem solving.
  • MSFriends is just a telephone call away ― ready to help you.
  • MSFriends has a call-back service for family members of those living with MS. Leave a message with the volunteer who answers and a trained volunteer who also has a family member with MS will call you back to provide support.

Connect today by calling the MSFriends helpline at 1-866-673-7436. All of your conversations are confidential.

Interested in becoming a peer support volunteer?

Please let us know if you are interested in volunteering as a peer support volunteer. The qualifications to be a peer support volunteer include:
  • Personal relationship to MS (person with MS, partner or family member of a person with MS).
  • Strong listening and communication skills; empathetic listener.
  • Knowledge of and access to Internet/e-mail technologies and equipment.
  • Dedication to the mission of the National MS Society and a desire to make a difference for those living with MS.
If you are interested in learning more, please contact us at peerconnections@nmss.org.




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National Multiple Sclerosis Society Research Studies

Participate in RESEARCH Studies funded by 
the National Multiple Sclerosis Society


Learn more of these studies by clicking here: 
http://www.nationalmssociety.org/Research/Participate-in-Research-Studies



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Cullman Alabama Doctor Speaks Out about LEMTRADA

Subject: Doctor speaks out about Lemtrada




Click the link to see article. Read all the way down to the link found at the bottom, then click that link.










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