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Saturday, November 15, 2014
Friday, November 14, 2014
Genzyme’s Lemtrada Approved by the FDA - GOOD News for MANY affected by MS That needed another Treatment Option.....
The genetic starting point for autoimmune diseases like multiple sclerosis (MS) and type 1 diabetes may be TK, according to a study published in Nature on October 29, 2014.
A multifaceted team of researchers developed a new mathematical formula to scour existing DNA databases in order to determine why inherited DNA variations contribute to disease. The sequencing techniques they developed examined epigenetic characteristics of specialized immune cells. Previously, the researchers had used a similar tool to study 21 different autoimmune diseases, and they were able to apply that method to the current project.
The researchers probed 39 genome-wide association studies (GWAS) – which each enlist thousands of participants – to identify DNA blocks implicated in genetic factors for diseases. GWAS rarely point to altered proteins, however. The researchers believe this is because only a few protein-encoding gene variants with these DNA codes have been investigated, let alone associated with autoimmune disease.
Investigators found the presence of specific gene variants differ among autoimmune diseases, which can further alter the functional ability of the immune system. This remained true even though the genetic variants are not within genes.
The majority of DNA changes related to autoimmune diseases occurred in the section of DNA known as “enhancers.” The enhancers of DNA – which is typically shaped in stringy molecules – allow DNA to fold so the various proteins can interact with each other. The enhancers also allow the bending of DNA to activate switches that can turn on specific genes. The enhancers the researchers identified as essential to DNA interaction had not been previously thought to have any functional role. -
“Once again, research is revealing new meaning in the world of DNA once thought of as junk — short, seemingly random DNA sequences that in fact serve meaningful roles in human physiology,” Alex Marson, MD, PhD, the corresponding author for the study, said in a press release.
- See more at: http://www.hcplive.com/articles/Multiple-Sclerosis-Stems-from-Immune-System-Not-Nervous-System#sthash.NepbNPou.dpuf
Patients Report Increased Quality of Life After Including Lifestyle and Alternative Medicine Approaches in Their Treatment Plan
Dr. Allen Bowling Outlines New Integrative Approach to Multiple Sclerosis (MS) Treatment
On average, a person who lives with Multiple Sclerosis does so for forty or more years. MS is a complicated disease that strikes many in the prime of their lives, while they are building families and careers.As a result, MS patients and their loved ones are often presented with a host of challenging and difficult transitions and emotional issues that are MS specific.
The MS Social Worker has many roles:
Educating and empowering MS patients and their families/caregivers
Keeping them up-to-date on the newest MS research, literature, and educational forums
Providing preventative techniques to avoid isolation and depression common to MS patients, improving their quality of life
Providing individuals and their families with counseling to address the many issues specific to the person living with MS
Providing education, knowledge, and support- Specific knowledge enables our MS Social worker to counsel and assist patients’ loved ones and/or caregivers to better support the patient
Keeping patients up to date on any changes/improvements to current therapies.
Our MS Social Worker has established relationships with pharmaceutical companies, is familiar with their drug therapies, is aware of the latest pharmaceutical advancements, and has knowledge of affordable pharmaceutical programs.
Referrals and connections to community Resource specific to MS, such as:
Group or individual hydrotherapy
Therapeutic horseback riding (Hippotherapy)
A monthly support group led by our MS Social Worker
Connecting Patients to a certified driver rehabilitation specialist for an evaluation (if adaptive devices are needed to continue driving)
Obtaining equipment and referrals to Home Health Services
Thursday, November 13, 2014
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Article source: http://multiplesclerosis.net/living-with-ms/whats-like/