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Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.
Saturday, December 20, 2014
First, to learn how to say these pharma names of these emerging therapies
Daclizumab (Dac-li-zu-mab) (trade name Zenapax)
is a therapeutic humanized monoclonal antibody. It is used to prevent rejection in organ transplantation, especially in kidney transplants. The drug is also under investigation for the treatment of multiple sclerosis.
Read more here
is a humanized anti-CD20 monoclonal antibody. It targets mature B lymphocytes and hence is an immunosuppressive drug candidate. It is under development by Hoffmann–La Roche's subsidiary Genentech, and Biogen Idec.
Ocrelizumab in MS: Encouraging Long-term Data
Friday, December 19, 2014
What is the role of dalfampridine (Ampyra) in multiple sclerosis patients? We asked four clinicians to comment: Brian Weinshenker, MD, of the Mayo Clinic in Rochester, Minn.; Neil Lava, MD, of Emory University in Atlanta; Andrew Goodman, MD, of the University of Rochester's Multiple Sclerosis Center; and Lana Zhovtis Ryerson, MD, of NYU Langone Medical Center's Multiple Sclerosis Comprehensive Care Center in New York City. The drug boosts walking ability in some patients, our panel agreed; trying it for a few weeks will identify those who respond without marked adverse effects.
Watch a video presentation on this subject by clicking here
What Happens During a Relapse?
When you experience a multiple sclerosis relapse (also known as an exacerbation or flare-up), it's because new damage in the brain or spinal cord disrupts nerve signals. That's why you might notice new symptoms or the return of old symptoms. A true relapse lasts more than 24 hours and happens at least 30 days after any previous relapses. Relapses vary in length, severity, and symptoms. Over time, symptoms should improve. Many people recover from their relapses without treatment.
Continue reading while watching a slideshow by clicking here
Thursday, December 18, 2014
Click here to listen and watch a video presentation
Relationship between iron accumulation and white matter injury in multiple sclerosis: a case-control study.
Iron in our bodies performs some fundamental functions such as transporting oxygen within the blood. However, in certain conditions, too much iron can harm us.
In healthy brains, iron is stored in the cells that produce myelin and in myelin sheaths. When, because of MS, these are destroyed, iron is released. This can lead to inflammation.
It has been reported that increased iron is associated with decreased brain volume. It can also precede brain atrophy, suggesting that it is involved with neurodegeneration.
Several studies have shown that magnetic resonance imaging (MRI) can indirectly detect increased iron in the brains of people with MS. However the role of iron in disease progression and development of disability is poorly understood.
In 2007, researchers from New York University pioneered a new MRI technique to detect iron increase in the deep brain areas.
The same team recently published a study of 31 patients with MS and 17 healthy volunteers. Using the new MRI method, they found increased iron in several deep brain areas of people with MS, but not in the volunteers.
This means that iron could be a useful biomarker, helping us understand the MS inflammation process. It might also be a useful marker of disease progression.
However, whether there is a definite iron accumulation in specific brain areas has to be further assessed in a larger number of patients.
Read the full article
Wednesday, December 17, 2014
Tuesday, December 16, 2014
- Legal 'electronic joint' developed to help ailments eased by cannabis
- It will help calm, relax and ease people's pain, but will not give a 'high'
- This is because it contains cannabidiol (CBD) which acts as a painkiller
- Does not contain psychoactive ingredient THC which gives a 'high'
- Product will be available to patients in France from January 2015
An 'electronic joint' made from hemp plants is being developed by a French manufacturer. It claims the e-joint, called KanaVape, will provide all the relaxing and painkilling effects of marijuana, without the high, as it does not contain the psychoactive ingredient THC
Sunday, December 14, 2014
Two Professionals Answer FAQs About Coping
Psychotherapist Allison Shadday and attorney Jeffrey Gingold adjusted their lives and goals after MS changed their careers. Here, they share their knowledge as well as their personal experiences about moving on.
Allison: One of the most difficult challenges you may ever face is the loss of your job due to MS. It is critical that you acknowledge your feelings and grieve, if necessary. Seek out the support of others who understand what you are going through, such as a local support group or an online forum.
While change is difficult, it is also important for you to be proactive during this transitional period to avoid feelings of victimization or hopelessness.
MS Help for 5 Common Problems
Multiple sclerosis is a chronic disease that attacks the central nervous system. An overactive immune system causes inflammation, which damages or destroys myelin, the fatty sheath that insulates nerves.
When that happens, “nerves can’t talk to each other – they can’t exchange signals from one neuron to the next,” explains Rodrigo Rodriguez Jr., M.D., a neurologist with Kaiser Permanente’s Bellflower Medical Center near Los Angeles.
As a result, MS patients may face a long list of nerve-related symptoms: pain or numbness, mobility problems, bladder dysfunction, vision changes, cognitive and emotional issues, dizziness and fatigue.
MS affects about 400,000 people in the U.S., and most are women, according to the National MS Society. The average patient is diagnosed in her 30s or 40s, Dr. Rodriguez says.
The condition is incurable, but the sooner drug therapy treatment begins, the better a patient will do over time, he notes.
The most commonly used medications for MS, known as disease-modifying agents, help “control the degree of inflammation and the rate of inflammatory attacks,” he says. “If these first-line agents don’t work, there are other medications that may be more aggressive in controlling inflammation.”
What is vitamin D's role in multiple sclerosis? Four experts gave us their thoughts: Nancy L. Sicotte, MD, of Cedars-Sinai Medical Center in Los Angeles; Peter Riskind, MD, PhD, of University of Massachusetts Medical School in Worcester, Mass.; Aaron Miller, MD, of the Icahn School of Medicine and Mt. Sinai Hospital in New York City; and Dennis Bourdette, MD, of Oregon Health and Science University in Portland. They agreed that the epidemiological evidence for an influence is indisputable, but whether supplements make a difference is still up in the air.
Learn more - WATCH this video presentation
What are the most under-recognized and undertreated aspects of multiple sclerosis? Three prominent MS specialists share their thoughts: John Corboy, MD, of the University of Colorado in Denver; Florian Thomas, MD, PhD, of St. Louis University; and Rock Heyman, MD, of the University of Pittsburgh Medical Center. Sleep disruption was a common theme, but bladder problems and cognitive impairment were named as well.
Watch this presentation here
MS in the News: What is the role of MRI is both diagnosing MS and following the course of the disease?
What is the role of MRI in both diagnosing multiple sclerosis and following the course of the disease? That's the question we posed to two prominent MS specialists: John Corboy, MD, of the University of Colorado in Denver, and Jerry S. Wolinsky, MD, of the University of Texas Health Science Center in Houston. They agreed that this imaging method has revolutionized the management of MS, both at onset and during its subsequent progression.
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Progressive multiple sclerosis represents a significant management challenge, so we asked three well-known researchers and clinicians to share their thoughts on the "best" treatment regimen: Stuart D. Cook, MD, of Rutgers-New Jersey Medical School in Newark; Tanuja Chitnis, MD, of Brigham and Women's Hospital in Boston; and Robert Fox, MD, of the Cleveland Clinic's Mellen Center for Multiple Sclerosis. They noted that drugs currently approved for relapsing-remitting MS may also hold promise for progressive disease, but a host of new treatment approaches are in the works, too.
Watch this video presentation found here:
Read more: Tributes paid to MS campaigner Glen | Redditch Standard
The MS World to recognize people like Glen, who Fight for them and who bring them knowledge ---