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Saturday, October 24, 2015
Anoctamin 2 occurred in about 16% of MS cases
CHICAGO -- Although its exact role isn't fully understood, the protein anoctamin 2 (ANO2) may have a role to play in multiple sclerosis, researchers reported here.
In a case-control study, about 16% of MS cases carried the protein, compared with only 3% of controls, Peter Nilsson, PhD, of the Royal Institute of Technology in Sweden, reported during a poster session at the Society for Neuroscience meeting here.
"Its role remains to be understood, but for sure we can say it's an interesting protein in context of autoimmunity and MS," Nilsson told MedPage Today. "But that's as far as we are today."
The work is part of the Human Protein Atlas, an international collaboration of researchers that has cataloged more than 25,000 antibodies, targeting proteins from more than 17,000 human genes -- about 86% of all human protein-coding genes.
The group also released the Mouse Brain Atlas, which captures 88 genes with in-depth protein profiling and 129 different mouse brain regions and cell types. Many of the mouse proteins have extensive homology with the human counterpart, the researchers said.
- You find yourself withdrawing from your friends and family.
- You lose interest in activities you used to enjoy.
- You feel blue, irritable, or hopeless.
- You notice you're losing or gaining weight.
- Your sleep patterns are changing.
- You get sick more often.
- You feel like you want to hurt yourself or the person you're caring for.
What You Can Do
Researchers from University of South Carolina examined RNA function in order to test the ability of axons to aid regeneration of nerves. The team set out to find a way to bridge what they called the “regenerative gap” between the peripheral nervous system and the central nervous system.
“If you injure a peripheral nerve, it will regenerate, spontaneously,” explained lead researcher Jeff Twiss in a press release. “It moves quite slowly, so it’s one of our objectives to speed it up, but it does regenerate. In contrast, with an injury to your spinal cord, it’s not going to regenerate.”
Short-chain fatty acids lessened symptoms of MS
Monday, October 19, 2015
- People with MS are at the center of their healthcare decision-making. (1)
- People with MS have access to a comprehensive network of providers and healthcare services focused on producing the best outcomes at affordable costs. (2)
- People with MS have access to comprehensive health insurance plans with affordable premiums, deductibles and other out-of-pocket costs. (3)
- Healthcare providers have greater awareness, resources and tools to enable the timely diagnosis, treatment and symptom management of MS. (4)
- People with MS have access to and receive high quality MS care regardless of disparities... (5)
- People with MS have access to high-quality long-term supports and services (...) in settings that best meet their needs and prevent financial hardship for the individual and family. (6)
the above information is found on the National Multiple Sclerosis website
CME event --- MS Think Tank: Putting it All Together - Understanding Treatment Options and Individualizing Therapy in MS