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Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

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Saturday, November 21, 2015

Empowering Columbia, South Carolina's MS Community with MS information


Dr. Walker's presentation begins at approximately 7 minutes into this video.



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Building Wellness and Quality of Life for MS Patients



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Mastering the prism of 7 VIBRANTs : mental, physical, emotional, spiritual, professional, financial, and social.

An MS Patient's story of his own beliefs





Master your life practicing the 7 VIBRANTs 


Nov 20, 2015 11:00 pm
Might sound bold, but I believe life mastery begins with an understanding that all we are, is what moves through us—our thoughts, rote beliefs, feeling, routine actions, and habits generated by the things we eat, drink, think, smell, listen to, and breathe.

Every moment influences who we are and is an opportunity to live the desired life mindful of the things entering and moving through us. If choices are made aligned with what you want, the desired life unfolds. Might be obvious, but how many of us are doing it?
Master Your Life, Jon Chandonnet, 7 VIBRANTsThink about it, very little that you allow into your body or moving through you is outside your ability to influence. Consider your situation. You’re a life generation machine responsible for the result. Do you take time to think about what you’re creating? Are you generating the desired life?

Master Your Life

By examining thoughts, actions and habits through the prism of 7 VIBRANTs, the primary states of being, countless opportunities appear to enhance your life vibrancy and live your desired life.

The 7 states are: mental, physical, emotional, spiritual, professional, financial, and social. Simply put: the 7 VIBRANTs. These states of being are based on eons of life experience passed through Sanskrit.

Since the 7 VIBRANTs reflect your life, looking at your holistic experience through them enables you to clearly see which is excelling and which is lagging. Like a prism, the VIBRANTs allow you to separate principal life elements and identify where to focus for enhanced vibrancy.

Focus thought and action to attract and reflect the most energy into your life. Get all aligned and focused to live your most VIBRANT life.

I assist people to take an objective look at their life, to ask the hard questions and determine if they’re living the desired life. If all’s good, great! If not, we get to work.
It’s in your hands.

My story

I looked Multiple Sclerosis, a disease bringing on paralysis, in the eye and asked what I needed to do to live a more VIBRANT, holistic life. MS is a disease that often leads to a great ambiguity, anxiety, and suffering. The medical and scientific community aren’t sure what causes it. They do know how to diagnose it, and I have it.

I denied the MS for years until it brought me to my knees and gave me no choice but to pay attention. After mindful listening, reflection, and action, what I found amazed me. I discovered I could influence the trajectory of the disease and life, through deliberate action. Let me be honest, it didn’t happen over night. It was like changing the destination of a speeding train headed through the Rockies to San Francisco from Denver and ending up in LA.

But I altered my course. The result was better health, clearer thinking, relationships that served me, work that fulfilled me, emotions that enriched my life and didn’t lead to unintended consequences, a financial existence of abundance and prosperity rather than anxiety and scarcity.

The point is, I shifted the trajectory of my life with failing health, a new bride, and a job that wasn’t headed in to good place and found a life of health, harmony, happiness and hope aligned with the 7 VIBRANTs.

Are you living your best life? Do you want to make changes? If so, let’s talk. My email address is jonchandonnet@yahoo.com.
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Friday, November 20, 2015

How Living With MS Is Like Cooking Mushrooms

Published Nov 19, 2015
Two of the most diverse ingredients in cookery are the egg and the mushroom. They’re also two of the most difficult to master.
While cooking 2.3 kilograms (5 pounds) of mushrooms for a dinner party today, I thought about how the lessons of cooking edible fungi have helped me live a life with multiple sclerosis (MS).
(Oh, I can hear you now: He’s likened living with MS to a baseball game, a dance, and even a sports team. But cooking mushrooms?! Where is he going now?)
First, of course, there are several different kinds of mushrooms. One must identify the edible (and delicious) from the unpalatable and even poisonous. Next, we must understand what we want out of our fungi: They can be so many things to so many different dishes that we must know how to best get what we need from what we have.
We cannot choose the type of MS we end up with, but the comparison that drew me from hob to keyboard today was in the cooking of mushrooms, not the choosing. That’s where my sense as a chef met my observation as a writer, and the idea simmered while my sauce came together.

Quickly Seared, or Slowly Stewed?

As I mentioned at the beginning, it takes much work to master the cookery of a mushroom. Many unflattering versions of the food have passed through my kitchen as I made — and learned from — mistakes.
In the beginning, I, like many people, thought cooking mushrooms involved using a hot pan and a little fat to quickly sear them so the water in the mushrooms evaporated quickly, leaving highly browned, tasty shavings of intensely mushroom-flavored, well … mushrooms.
Today, I often prefer to cook mushrooms slowly so they release their moisture, and so they can mingle with aromatics that can be concentrated — then reabsorbed — into their spongy bodies to create something deeper and richer than themselves.
Similarly, my old life may have been a series of quick sautés of individual experiences, hurried side dishes, and a searing pace.
But today, I appreciate the slow gaining of experience, the mingling with interesting companions, and the right amount of heat and time to create something wholly different from a simple combination of single ingredients. More and more, this slow, warm mingling of people and places affords me deeper connections, and the dish I find myself enjoying nowadays has a richness and complexity because of contact with people like us.

Making the Most of Living Slowly

The analogy takes a bit of a turn when I realize that while I may have mastered the cooking of ’shrooms, I don’t yet have a perfect batting average with the “living with MS thing.”
Life with MS has forced me to slow down. It’s not something I chose. But I can choose how to use my time to make my life full and rich, even if it’s not the same as the way I used to do it.
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Novel Protein Suppresses MS in Mouse Model, Inhibits Neuroinflammation in Spinal Cord


IL-32 might be a potential new therapeutic avenue for MS
Nov 18, 2015

<span class="entry-title">Novel Protein Suppresses MS in Mouse Model, Inhibits Neuroinflammation in Spinal Cord</span><span class="entry-subtitle">IL-32 might be a potential new therapeutic avenue for MS</span>  November 18, 2015
 In a recent study entitled “Myelin oligodendrocyte glycoprotein (MOG35-55)-induced experimental autoimmune encephalomyelitis is ameliorated in interleukin-32 alpha transgenic mice,” a team of researchers investigated whether interleukin (IL)-32, a cytokine with an established role in rheumatoid arthritis, has a protective function in a mouse model of human multiple sclerosis (MS). The study was published in the journal Oncotarget.
MS is a neurological autoimmune disease characterized by immune destruction of themyelin layer within nerve cells, leading to a wide range of neurological symptoms (affecting sensory, motor, autonomic, and neurocognitive functions) that usually manifests between the ages of 20 and 40 years old. Currently, MS affects approximately 350,000 individuals in the United States.
IL-32 is a novel cytokine (cytokines are small proteins with key functions in cell signaling) expressed in a variety of human organs1 — including the spleen, thymus, leukocyte, lung, small intestine, colon, prostate, heart, placenta, liver, muscle, kidney, pancreas, and brain. IL-32 expression is increased in rheumatoid arthritis, a chronic inflammatory disorder, where its levels correlate with clinical and histological markers of the disease. The role of IL-32, however, on central nervous system injuries and demyelination is currently poorly understood.
In this new study, a team of researchers investigated how IL-32α may affect MS pathogenesis. To this end, they induced in vivo experimental autoimmune encephalomyelitis (EAE), an experimental and widely accepted mouse model of MS, by injecting mice with encephalitogenic peptide, MOG35-55. The same strategy was used in a transgenic mouse that overexpressed the human IL-32α protein (IL-32α transgenic mice).
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Tips for a Healthy Pregnancy with Multiple Sclerosis (MS)


Before Pregnancy

Talk to your doctor. If you want to start a family, or add to it, let your doctor know. Many MS medications -- like glatiramer acetate (Copaxone), interferons (AvonexBetaseronRebif) and natalizumab(Tysabri), and others -- aren't safe for your baby. You'll need to stop taking them before you try to get pregnant. Some others, like teriflunomide (Aubagio), are risky even for men who want to father a child.
Connect. If you aren't already part of a support group, now's a good time to seek one out. Talk to other women with MS who have kids. Get tips on how to manage pregnancy and life with a new baby.

Plan for the future. What would happen if you had a flare after your baby's birth? Do you have family and friends who can lend a hand if you need it? It's good to choose your go-to back-ups before you get pregnant.

During Pregnancy

Appreciate the benefits. Pregnancy naturally seems to ease MS symptoms for many women, especially in the third trimester. So if you get a reprieve, enjoy it.
Get treatment if you need it. Let your doctor know if you don't feel good or have problems. Being pregnant can be uncomfortable for anyone. If you have an issue, don't ignore it.
If you have a hard time getting around, it may get even tougher late in your pregnancy. A cane or other device may help you.
Plan for delivery. Most women with MS give birth just like anyone else. But muscle weakness can come into play. You may have a higher likelihood of needing a C-section. If your condition has caused a loss of feeling in your pelvis, you may need to be watched more closely the last month of your pregnancy.

After Your Baby's Birth



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Speech and Swallowing Problems From MS

People with multiple sclerosis, or MS, often have trouble swallowing, a problem called dysphagia. It can also lead to speech problems. It happens when the disease damages the nerves in the brain and spinal cord that make these tasks happen.
For some people, these problems are mild. Others have a harder time dealing with severe symptoms. But treatments and techniques can help you improve your speech and make swallowing easier.

Symptoms of a Swallowing Problem

You might:
  • Cough or choke when you eat
  • Feel like food is lodged in your throat
  • Get a lot of lung infections, like pneumonia, that you can’t explain
When you can’t swallow properly, you might inhale food or liquids into your windpipe instead of getting them down your esophagus and into your stomach. Once in the lungs, they can cause pneumonia or abscesses. You could also be at risk for malnutrition or dehydration because your food and water aren’t getting to your stomach.

Symptoms of Speech Problems

The kinds of speech problems MS causes can vary depending on which part of the brain is damaged. Someone with the disease might have mild trouble with words or severe problems that make it hard for them to speak and be understood. A problem that’s subtle in the beginning might get worse over time.
People with MS usually have a few distinctive language problems:
  • “Scanning" speech, when a person’s normal speech pattern is disrupted with long pauses between words or syllables
  • Slurring words. It usually happens because of weak tongue, lip, and mouth muscles.
  • Trouble changing tone of voice
  • Nasal-sounding speech

Getting a Diagnosis

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MS Society Invests in Research into Underlying Causes of Disease


<span class="entry-title">MS Society Invests in Research into Underlying Causes of Disease</span><span class="entry-subtitle">6 of 16 selected projects share £1.98 million society award</span>

The Multiple Sclerosis Society (MS Society) in the United Kingdom recently announced the investment of £1.98 million in new MS research. The 16 projects awarded funding through the MS Society’s 2015 grant round were thoroughly evaluated in a rigorous review process.
In total, 58 projects applied for MS Society grants this year. All applications were reviewed by a panel of experts who assessed the projects in terms of high scientific quality, sound evidence base, and alignment with the MS Society’s research strategy. In addition, the applications were reviewed by individuals living with MS as a way to guarantee that those selected were of relevance to people directly suffering directly from this condition.
In the end, 16 projects secured  a total of £1,979,879 in funding and can be divided into fourcategories: cause, cure, care and services, and symptom management, and are expected to get underway in the coming months.
Six projects were related to research on the underlying causes of MS. One, entitled “Establishing a zebrafish model to study brain inflammation” and led by Dr. Anne Astier at the University of Edinburgh, received £36,622. The goal of this project is to investigate the role of CD46, a protein present in some immune T cells that move into the brain and attack the protective myelin sheath covering nerve fibers, causing inflammation. CD46 is known to be involved in this process, and the team hypothesized that this protein might not be properly activated in MS. Researchers will use zebrafish as an animal model to conduct their studies in a living organism. This project is especially important because some MS therapies are based on an interaction with the CD46 molecule and the blockade of immune cell migration into the brain. A better understanding of this process might help optimize treatment, making it more specific and reducing possible side effects.
Another project, titled “Does vitamin D control the movement of immune cells?,” also led by Dr. Astier, was awarded £98,904 and will focus on how immune T cells migrate into the brain and spinal cord, and the possibility that vitamin D may be involved in controlling such processes.

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Treatment adherence in multiple sclerosis: a survey of Belgian neurologists

Authors Decoo D, Vokaer M

Received 8 July 2015

Accepted for publication 25 September 2015

Published 19 November 2015 Volume 2015:9 Pages 1669—1676

DOI http://dx.doi.org/10.2147/PPA.S91973

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Safaa Khaled

Peer reviewer comments 2

Editor who approved publication: Dr Johnny Chen

Danny Decoo,1 Mathieu Vokaer2

1Department of Neurology and Neurorehab, AZ Alma, Sijsele, Belgium; 2Multiple Sclerosis Clinic, Edith Cavell Hospital, CHIREC group, Brussels, Belgium


Background: Poor treatment adherence is common among patients with multiple sclerosis (MS). This survey evaluated neurologists’ perception of treatment adherence among MS patients.

Materials and methods: This questionnaire-based survey of Belgian neurologists treating MS patients was conducted between June and July 2014. Face-to-face interviews with the neurologists were based on a semistructured questionnaire containing questions regarding the perception of the treatment-adherence level.
Results: A total of 41 neurologists participated in the survey. Of these, 88% indicated frequent discussions about treatment adherence as beneficial for treatment efficacy. The mean time spent on the treatment-adherence discussion during the initial consultation was 11 minutes, with 24% of doctors spending 5 minutes and 24% of doctors spending 10 minutes discussing this issue. The majority of neurologists (56%) perceived the adherence level in MS as good, and 12% perceived it as excellent. The majority of neurologists (64%) indicated intolerance as a main cause of poor adherence, and all neurologists reported insufficient efficacy as a consequence of nonadherence. The importance of adherence in the neurologists’ practice was evaluated on a scale of 1–10, with 1= “not very important” and 10= “very important”: 44% of doctors indicated a score of 10, and the mean score was 9.0.

Conclusion: Belgian neurologists consider treatment adherence in MS as essential for the benefits of therapies. However, although neurologists are aware of the consequences of nonadherence, they generally spend limited time discussing the importance of treatment adherence with their patients.

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Macrophages, Monocytes Amplify Neuroinflammation in Multiple Sclerosis


Macrophages, Monocytes Amplify Neuroinflammation in Multiple Sclerosis November 19, 2015

Transcription factor Nr4a1, which regulates the production of norepinephine in macrophages, may be a good target for multiple sclerosis treatment, a mouse model suggests.  
Study data, published in Nature Immunology, indicates a previously unknown role for macrophages in neuroinflammation.
“Although multiple sclerosis (MS) is generally considered a T cell-driven disease, many studies have shown that monocytes and monocyte-derived macrophages are also crucial for the development of MS,” Catherine C. Hedrick, PhD, of the Division of Inflammation Biology at La Jolla Institute for Allergy and Immunology in La Jolla, CA told Neurology Advisor.  “It is increasingly clear that macrophages recruited in response to inflammation are fundamentally different from homeostatic local microglia within the CNS, and therefore should get special attention for their relevance in initiation and progression of CNS autoimmunity.”
Hedrick and colleagues hypothesized that Nr4a1 may be involved in the interaction of the immune system and sympathetic nervous system in the setting of neuroinflammation. Norepinephrine has previously been shown to play a role in experimental autoimmune encephalitis (EAE), the rodent model of MS. Using an established passive rodent module of EAE to better understand the role of Nr4a1 in CNS autoimmunity, the investigators conducted a series of experiments, including intravital microscopy to observe CNS damage and leukocyte infiltration, flow cytometry to look at the expression of tyrosine hydroxylase (TH), and a mouse macrophage cell line to understand Nr4a1's regulation of TH.
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Thursday, November 19, 2015

How does MS Affect Your Walking?

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Monday, November 16, 2015

Ask the MS Clinician's Digest - Topic Learning about MS Relapse and Treatments


Video recorded on September 26, 2015



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Ask the MS Clinician's Digest - Topic Learn about Multiple Sclerosis Infusion Treatments


A Video recorded interview

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Sunday, November 15, 2015

Ann Romney spearheads landmark MS study

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November 15th
Karen Weintraub, Special for USA TODAY


For three years after she was diagnosed with multiple sclerosis in 1998, Ann Romney was miserable. An active mother of five, the disease so exhausted her, she could barely get out of bed.

But after that horrible time, Romney, wife of former presidential candidate Mitt Romney, began to bounce back. She has fared well since, supporting her husband on the campaign trail, doing charitable work and playing with her grandchildren.

Despite tremendous advances in medication, doctors still don’t know why the early stage of MS can wax and wane so much, and why some people with MS end up debilitated within a few years and others can continue to thrive for decades.

Romney has volunteered to be one of the first of 2,000 participants in a new study aimed at unraveling that mystery.

“We’re hoping this will serve as a foundation for understanding MS in the modern era in a way that has not been understood,” says Howard Weiner, director of the MS center at the Brigham and Women’s Hospital in Boston and co-principal investigator of the new SysteMS study.

The research is a collaborative effort from the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital in Boston; the drug company Biogen, which makes several MS medications; and Google, which will handle the sensor tracking and data analysis. Biogen and Google will cover the undisclosed cost of the multi-year SysteMS study.

Volunteers will wear activity sensors, answer frequent questionnaires and allow deep biologic profiling of their genes, immune activity, blood, urine, saliva and stool.
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Maintaining Your Healthy Habits This Holiday Season

Every year people both look forward to AND dread the holidays. There’s the excitement of visits to (or from) family and friends, fun holiday events, and delicious delicacies that are enjoyed only this time of year.

But along with all that good stuff comes stressful travel and/or preparing for guests, an overflowing calendar, and food items that may not sit well with you. Sound familiar? There must be a way to keep yourself from getting rundown and run off the path of healthy habits.  Here are a few ideas that might help:

·         When it comes to food, being prepared is key. The combination of alcohol, finger foods and desserts can be problematic even for those who are most careful. After all, it’s a party!
o   Before you arrive, be sure that you have food in your stomach and you’re not “starving.”
o   Remain attentive to what you’re drinking, which in turn can help you be mindful of your food choices.
o   Finally, keep treats as treats – a small amount is often enough to satisfy a craving. Enjoy a bite of that special dessert or food!

·         Book ME time. Each day, be sure to carve out time for your own period of rejuvenation. Escape to a quiet room and you’ll hopefully emerge ready to enjoy the rest of the day.
o   Don’t be afraid to call it quits – your body knows what it needs, and you know your body. Pay attention to what it tells you, and then let others know if it’s time for a break.

When you plan in advance, and plan for your OWN needs, you’re most likely to enjoy the holidays!

In Health,
Elissa


Are there habits you’ve adopted over the years that you’d like to shed? Goals that you want to accomplish? As a Health Coach, I can help you make significant and meaningful change in your life. Take a look at www.HealthElissa.com or http://www.Facebook.com/HealthElissa. I look forward to talking with you.




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