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Friday, April 15, 2016

Biogen Data at 2016 AAN Annual Meeting Highlight Its Expansive Portfolio of MS Therapies That Meets Diverse Needs of Patients

− Strong and Sustained Efficacy of TECFIDERA® Supported by Clinical Data and Real-World Evidence –
− New ZINBRYTA™ Data Show Impact on Cognitive Outcomes and Reversibility of its Targeted MOA −


Tuesday, April 12, 2016 7:30 am EDT

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Biogen (NASDAQ: BIIB) will present new data demonstrating the breadth and diversity of its marketed and pipeline multiple sclerosis (MS) therapies at the 68th annual meeting of the American Academy of Neurology (AAN) in Vancouver, Canada, the company announced today. These data support Biogen’s established portfolio, which includes the most-prescribed oral MS treatment in the world, TECFIDERA® (dimethyl fumarate), and demonstrate the ability of its differentiated products to meet the distinct needs of people living with MS.
“MS is a complex, life-long disease that affects each person differently. Because people with MS have diverse treatment needs, it is critical that they have a variety of therapeutic options available that not only provide robust efficacy and different mechanisms of action, but also offer the flexibility to transition to another treatment, if needed,” said Ralph Kern, M.D., senior vice president, Worldwide Medical. “With the world’s leading MS portfolio and growing pipeline, Biogen continues to focus on MS care to impact the greatest number of people living with MS globally.”
TECFIDERA data will showcase its strong and sustained efficacy in newly diagnosed MS patients, reinforcing that earlier treatment with TECFIDERA is critical to improve long-term clinical outcomes. In addition, real-world comparative effectiveness data will show that TECFIDERA is associated with significantly lower annualized relapse rates (ARR) relative to glatiramer acetate, interferon β and teriflunomide, and ARR were similar between TECFIDERA and fingolimod. These data support the established combination of benefits TECFIDERA offers, including strong and sustained efficacy, a well-characterized long-term safety profile and oral convenience.
With nearly 10 years of clinical experience, TYSABRI® (natalizumab) data will highlight real-world evidence demonstrating its proven long-term efficacy and safety, particularly when used earlier in the course of the disease. Additional Biogen data presentations will highlight the impact of ZINBRYTA™ (daclizumab HYP) on cognitive outcomes and its targeted mechanism of action (MOA), with data showing it did not cause broad immune cell depletion and that its effects on total lymphocyte counts were reversible within approximately eight to 12 weeks upon treatment discontinuation.
Highlights of Biogen’s AAN Data for Presentation:
       Continue reading of Biogen current and future MS treatments by clicking here

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