Please visit our MS learning channel on Youtube, which provides hundreds of topics from our education programs, that were video-recorded and archived here: www.youtube.com/msviewsandnews -- Be empowered with MS news by registering with us: www.register.msviewsandnews.org

joomla ecommerce template -- Scroll left side of this blog for needed resources. Also, use our 'search by topic' tool, to find specific information.

Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

============================================================

Friday, December 2, 2016

Could ALS Be Caused By A Virus?


                                                                  
  

Click here to receive MS news via e-mail



December 2, 2016
Written By:  Jack Florin, Neurologist, Headache Medicine and Multiple Sclerosis Specialist
Could that same virus be the antigen that triggers the immune response in MS?

If confirmed, these observations carry monumental implications.

A recent report was published in Neurology, October 25, 2016, by lead author Lauren Bowen, MD. Five patients with HIV infection who later developed an ALS-like disease were reported. Three of the five patients who received anti-retroviral therapy within 6 months of onset had reversal of their symptoms. The other two had slow progression over several years. In 3 of the patients, blood levels for the human endogenous retrovirus K (HERV-K) were elevated. Further, those levels responded to antiviral therapy. This is an archaic virus that has been integrated into the human genome for thousands of years and, in fact, endogenous retroviruses constitute approximately 8% of the human genome. The specific HERV-K group is the most recently required of these retroviruses.

ALS associated with HIV infection has been recognized for over 15 years, but the association with HERV-K virus is new.

Regarding MS, studies are controversial, but some seem to indicate that the virus is in the brain and that it triggers the immune response, and this supports the concept that MS is “inside-out” rather than “outside-in.” This theory explains progressive MS better.


It does not take much imagination to envision patients and families of patients with ALS clamoring for treatment with anti-retroviral therapy. According to Drs Berger and Power in an editorial in the same issue, commenting upon the article by Bowen, patients with ALS that is not associated with HIV infection should receive this treatment only in a clinical trial.


Keep in mind that much is lost between the cup and the mouth

Article Source 






MS Views and News
Providing educational information, resources and services for those affected by MS
MS Views and News is MAKING an IMPACT on those affected by Multiple Sclerosis

No comments: