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Saturday, December 3, 2016

Multiple sclerosis: Newly discovered signal mechanism causes T cells to turn pathogenic


                                                                  
  

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Date: December 1, 2016
Source:
Technical University of Munich (TUM)
Summary:
Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. In this case, modified T cells destroy the myelin sheath surrounding nerve cells. Myelin protects the neural pathways and is thus essential to the ability of nerve cells to transmit information. A recent study has demonstrated that a substance known as interleukin 6 (IL-6) plays an important role in instructing T cells to cause damage to myelin sheaths in the central nervous system.
Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. In this case, modified T cells destroy the myelin sheath surrounding nerve cells. Myelin protects the neural pathways and is thus essential to the ability of nerve cells to transmit information.
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