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Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

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Friday, January 15, 2016

How Does MS Become More Advanced?

How Multiple Sclerosis Changes Over Time



Multiple sclerosis (MS) is different for everyone who has it. The symptoms it causes and when they flare up vary not only between people but also throughout one person’s life. This means it can be hard for doctors to diagnose someone with the condition. They might say you "probably" or "possibly" have MS.

Your diagnosis is based on the symptoms you have, how and when they flare up or improve, which of your body’s functions give you trouble, and your test results. There’s no way to predict how your condition will change throughout your life. It may take time, but as your doctor gets more clues about the type of MS you have, you can have a clearer idea of how it will affect you in the coming years.

The way the disease changes and gets worse is different for each of the four types of MS:

Relapsing-remitting MS: People with this type have attacks when their symptoms get worse, called relapses, followed by full, partial, or no recovery. These flares seem to change over several days to weeks. Recovery from an attack takes weeks, sometimes months, but symptoms don’t get worse during this time. Most people have this type when they’re first diagnosed with MS.

Primary-progressive MS: In this type, symptoms gradually get worse without any obvious relapses or remissions. About 15% of all people with MS have this form, but it’s most common type for people diagnosed after age 40.

Secondary-progressive MS: People who get this type usually start with relapsing-remitting MS. Over time, symptoms stop coming and going and begin getting steadily worse. The change may happen shortly after MS symptoms appear, or it may take years or decades.

Progressive-relapsing MS: This is the least common form of the disease. Symptoms steadily get worse, but people also have flares that may or may not be followed by some recovery. At first, people with this type may seem to have primary-progressive MS.

What Is a True Relapse of Multiple Sclerosis?

An MS relapse starts when nerves in the brain and spinal cord get inflamed (swollen or irritated). Then, those nerves lose the coating, called myelin, that surrounds and protects them. A plaque forms around them instead.
Learn more from WebMD



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Does Your Diet Affect Your MS?

By Melinda Wenner Moyer
WebMD Feature
Reviewed by Neil Lava, MD
It’s natural to want to do anything you can to help tame your multiple sclerosis symptoms. You take your medicine and keep up with your doctor visits. Would it also make a difference to change what you eat?
Although no diet is proven to give you relief, some nutrients may make a difference for better or worse.
There is no such thing as a special “MS diet” that has been proven to improve symptoms.  Most doctors recommend you eat a low-fat, high-fiber diet similar to the one recommended for the general public by major medical organizations.
Go for a variety of fruits and vegetables, whole grains, low-fat dairy products, skinless poultry and fish, nuts, and legumes. Avoid items that are highly processed and high in saturated fat.
Gluten-Free May Not Help
Ditching gluten is popular, and for people who have celiac disease, it’s a must. But no research shows that it improves MS symptoms.
Several studies have found that people with MS aren’t more likely than anyone else to be sensitive to gluten. So if you decide to go gluten-free, MS probably is not the reason to do so.
Should You Go Paleo?
These plans favor lean meats, nuts, and berries. The approach stems from the idea that your body can process these ancient staples better than modern items, such as dairy products and processed carbohydrates.
There isn’t much research on Paleo diets and multiple sclerosis. In one small study, people with MS who followed the diet for a year said they were less tired than people who didn’t. But that might not just be about their diet, since they also exercised, stretched, and meditated during the study.
Mediterranean Diet
This traditional diet is one of the healthiest in the world. Although it’s not specific to MS, it’s good for you in general.
You’ll eat a lot of fish, whole grains, fruits and vegetables, legumes, and olive oil. There’s no research on how this diet affects MS in particular. But many studies show that it’s good for you overall and may help lower inflammation.

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Stubborn or Stupid - a Patient's testimonial


Stubbornness is a trait often revered in those with a disability. That attitude of defiance that we give to our disease so we can power through the tougher times. That ability to raise our middle finger and shout “Take that, MS!” as we soldier on in our quest for normalcy. Alas, there’s a fine line between stubborn and stupid, especially when you have multiple sclerosis—and I’ve got both pretty well covered. Don’t make my mistakes…

Walking around the kitchen, eschewing your walker, cane, even the helpful wall? Stubborn! Falling in said kitchen and breaking a leg? Ah, stupid. Killing a big, very hairy spider for your wife despite your physical limitations? Stubborn! Slipping and falling after cleaning up said spider, bumping your head necessitating a trip to the ER before you bleed out? Ah, stupid. Decorating the Christmas tree, insisting on hanging every sharp, star-shaped ornament personally even though you have crummy balance? Stubborn! Teetering into the Christmas tree, bear hugging it before knocking it completely over onto your unsuspecting dog, while in the process impaling yourself on multiple stars, glass icicles, and a pointy Santa that gets lodged deep inside your left nostril? That would indeed be stupid, especially since I don’t even have a dog. Thankfully I’ve avoided such an accident to date. (Memo to self: don’t do that.)


Read more from here: http://activemsers.blogspot.com/2016/01/stubborn-or-stupid.html





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Thinking of the Future

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If you want to attend this Dinner Gala honoring:
 Brian Steingo MD of Neurology 
and Don McNeal, 
Former Alabama Crimson Tide Hall of Fame
/ Miami Dolphins NFL,

You can wait for a postal invitation Or you can simply
register online:  www.champions.msvn.org
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Thank you for helping us get closer to our goals
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MS Views and News 
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concerning Multiple Sclerosis (MS).  Through partnering relationships, MSVN provides education, 
advocacy and service to empower and enhance the quality of life of the MS community.

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Thursday, January 14, 2016

Ask the MS Clinician Series - Topic: Injectable MS Treatment Options


Video Recorded on December 30, 2015

MS Clinician Digest Interview with James (Stuart) Shafer, MD from Vero Beach, Florida
Topic: Injectable MS Treatment Options




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Ask the MS Clinician - Topic: ORAL Multiple Sclerosis (MS) Medications


Megan R. Weigel, DNP, ARNP-c, MSCN - expertly answers questions regarding current Oral medications and what looms in the pipeline

Video Recorded on December 15, 2015






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Simple MS Blood Test Said to Be Able to Diagnose Disease at Symptom Onset

IQuity Labs ready to launch series of early stage autoimmune disease diagnostic tests in 2016

<span class="entry-title">Simple MS Blood Test Said to Be Able to Diagnose Disease at Symptom Onset</span><span class="entry-subtitle">IQuity Labs ready to launch series of early stage autoimmune disease diagnostic tests in 2016 </span>IQuity Labs, which specializes in diagnostic tests for autoimmune and other diseases, recently announced that it has received $2 million in seed funding to support the launch of its test panels, diagnostic tests designed to confirm the presence or absence of disease at the very onset of symptoms. The first to debut, in early to mid-2016, will be a test for multiple sclerosis (MS).
“People often search for years to find answers that will help them address symptoms related to autoimmune disease,” said IQuity’s CEO, Dr. Chase Spurlock, in a press release. “It’s our goal to equip providers with a tool to diagnose patients faster so they can lead happier, healthier lives.”
Panels to diagnose other autoimmune diseases will be released during the second half of 2016. The company also plans to launch tests — still under development — for diseases related to the fields of gastroenterology and rheumatology later this year.
READ MORE



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MS Study Questions Safety of Bacteria commonly used to increase immune response

In a recent study, a team of researchers argued that, contrary to what has been proposed,subclinical Bordetella pertussis colonization is an important cause of multiple sclerosis (MS). The study, “The potential role of subclinical Bordetella Pertussis colonization in the etiology of multiple sclerosis,” was published in the journal Immunobiology.
The bacteria Bordetella pertussis and its secreted toxin have been extensively used within the last 50 years as a potent adjuvant, or substance added to a vaccine to increase the body’s immune response to it. When co-administered with neural antigens, the bacteria induces neuropathology in experimental autoimmune encephalomyelitis, the key animal model for human MS.
Researchers now hypothesize that subclinical Bordetella pertussis nasopharyngeal colonization is not innocuous to hosts, and can actually behave as a human neuropathogen causing MS.
The team reviewed three epidemiological cases that offer evidence supporting their hypothesis. The first is the major MS-related epidemiologic phenomenon of the last century — the MS epidemic in the Faroe Islands during and immediately after World War II. According to the article, authors who studied the outbreak noted that “MS is the rare late outcome of a specific but unknown infectious disease of adolescence and young adulthood.”
The second evidence comes from ---  LEARN MORE




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MS Progression Halted Using Stem Cells Derived from Gum Tissue

JANUARY 13, 2016


 Study reports that cells isolated from periodontal ligament stopped disease progression in mice

A new source of stem cells, the mesenchymal stem cells (MSCs) isolated from the human periodontal ligament (hPDLSCs), offers a potential treatment capable of halting multiple sclerosis (MS) progression. The study, “Alternative source of stem cells derived from human periodontal ligament: a new treatment for experimental autoimmune encephalomyelitis,” was published in the Stem Cell Research & Therapy journal.
Current treatments for MS are administered only as a palliative relief, without a cure, and many are associated with adverse side effects. The development of techniques that allow for harvesting and culture of MSCs, especially those derived from the bone marrow, aids investigations into its properties in promoting tissue repair and disease control in the established mouse model for human MS, the experimental autoimmune encephalomyelitis (EAE) model.
LEARN MORE




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10 Ways to Boost Your Exercise Motivation

You know exercise is good for you. Doing it, though, is another thing.
To stick with an exercise routine, you need to get out there when that little voice inside you says, "I'll do that tomorrow. Or the day after -- maybe."
Motivation does that, and it's not about just powering through.

1. Lighten Up Your Goals

Your fitness goal may be too big for you right now, especially if you're new to exercise.
Beginners "want to go for maximal goals, but they tend to get overwhelmed," says Gerald Endress, exercise physiologist at Duke Center for Living in North Carolina.
So don’t start off trying to work out an hour every day. Instead, set more reasonable, achievable goals, like exercising 20 to 30 minutes two or three times a week.

2. Track Your Progress

Chart your workouts, whether you do it online or in an old-school fitness journal. Seeing improvements, whether running faster, doing more reps, or working out more often, makes you want to keep going.

3. Delete Guilt

Get real. You're going to miss a day or two. If you accept that there will be some side steps on your fitness journey, you’ll be better prepared mentally to deal with setbacks, Endress says.
Don’t let a misstep be an excuse for giving up.

4. Focus Only On Yourself

There will always be someone fitter, faster, or more flexible than you.
Don’t compare yourself to them, Endress says. Forget about them. Do not let them deter you from your goal. Your workout time is for you, and about you.

5. Get a Cheering Squad




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Wednesday, January 13, 2016

Can Cannabinoid Chewing Gum Treat Multiple Sclerosis Pain and Spasticity?


MedChew Rx, by AXIM Biotechnology, Inc., the world’s first patented cannabinoid release chewing gum for pain and spasticity in multiple sclerosis (MS), is moving into clinical testing. If all goes well, the company plans for a global release date of 2017.
<span class="entry-title">Can Cannabinoid Chewing Gum Treat Multiple Sclerosis Pain and Spasticity?</span><span class="entry-subtitle">AXIM Biotech hoping for 2017 release of its pain-relief gum, MedChew Rx, moving into clinical testing</span>
Medical cannabis is believed to have considerable promise as a therapy for difficult-to-treat pain associated with disorders like MS and other conditions that cause nerve pain. AXIM Biotech, based in New York and Ridderkerk, the Netherlands, says that if approved as expected by the FDA (U.S. Food and Drug Administration) and the EMA (European Medicines Agency), MedChew Rx — formulated with 5 mg of cannabidiol (CBD) and 5 mg of tetrahydrocannabinol (THC) — will be marketed as a pharmaceutical drug for treating MS.
AXIM and MedChew Rx were profiled in a feature article this week by the Reuters global news agency’s Natalie Grover, documenting AXIM’s early testing of MedChew Rx, being conducted in the Netherlands, and comparing AXIM’s product to U.K.-based GW Pharmaceuticals’ Sativex, which is not as yet approved in the United States, as well as to noncannabis-based Botox, and baclofen, a muscle relaxant.
Among the estimated 400,000 people in the U.S. and 2.5 million worldwide with MS, roughly 80 percent suffer from spasticity, which is frequently treated with baclofen.  AXIM anticipates that MedChew Rx could amount to more than $4.8 billion per year in the U.S. market (an estimate it derives from Sativex’s four daily treatments at $8.24 per dose), although Ms. Grover notes that state health systems in some countries, including GW Pharmaceuticals’ home market, do not consider the drug cost-effective enough to justify coverage.


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Suppressing Immune Disorders in Multiple Sclerosis

There may be an easy way to treat immune related disorders in mice models of multiple sclerosis (MS), according to a study published in the Journal of Immunology 

Research. Researchers from the University of Florida used an infusion of spleen cells in combination with an autoantigen to block MS in mice models. The process used attaches disease related protein fragments, the autoantigens, to spleen cells to prevent MS. In mice models, MS causes brain and spinal cord inflammation, similar to human MS. The process was able to “dramatically reverse” MS in its early stages in the mice, the researchers said. - 



See more at: http://www.hcplive.com/medical-news/suppressing-immune-disorders-in-multiple-sclerosis#sthash.gJ4Po6M9.dpuf





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CME presentation: "So Many Options, So Little Time: Clinical Considerations to Assess MS Therapies"


MS leaders e-mail logo header 

Dear MS-Leaders Registrant,
Can you correctly answer this question:
Which of the following statements with respect to MS treatment is CORRECT?

A. Putatively remyelinating therapies have not yet begun investigation in MS
  
B. Approximately 5% of patients experience new or increased depression within 6 months of initiating interferon beta-1b therapy
 
C. Teriflunomide is rapidly eliminated from the hepatobiliary circulation

D. Male mediated teratogenicity is a concern with teriflunomide

Participate in our Clinical Dialogue and eCase Challenge to learn the answer to this and other questions related to MS therapy.

Earn Up to 1.0 Free CME or CNE Credit!

Postgraduate Institute for Medicine and Medical Logix, LLC, are currently offering this educational program certified for CME and CNE credit, at no charge to participants:


Activity valid for credit through February 6, 2016

Acknowledgement of Commercial Support
Supported by an independent educational grant from EMD Serono.
Intended Audience
This activity is intended for physicians, advanced practice nurses, physician assistants, registered nurses, and other allied healthcare professionals involved in the diagnosis and treatment of multiple sclerosis.
Accreditation Statement
ACCME - This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Postgraduate Institute for Medicine and Medical Logix, LLC. Postgraduate Institute for Medicine is accredited by the ACCME to provide continuing medical education for physicians.
ANCC - Postgraduate Institute for Medicine is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.
Credit Designation Statement
ACCME - The Postgraduate Institute for Medicine designates these enduring materials for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
ANCC - This educational activity for 0.5 contact hours is provided by Postgraduate Institute for Medicine (per web activity). Pharmacotherapy contact hours for Advance Practice Registered Nurses will be designated on your certificate.
Format and Method of Participation
There are no fees for participating and receiving CME or CNE credit for this activity. During the accreditation period, participants must read the learning objectives and faculty disclosures and review this internet-based activity. To take the post-test, please click on the post-test button below the slide window of the player. Complete the post-test and evaluation and attest to the amount of time spent in the activity. Upon receiving a score of 70% or above, print your CME or CE certificate.

For CME or CNE questions, please contact Postgraduate Institute for Medicine at: information@pimed.com or (303) 799-1930. 
Please keep in mind that you will need to login with your email address and password to access this program.  If you forgot your password, click on the 'Forgot Password' link in the top right corner of the site.
We hope you enjoy these informative educational programs! 

The MS-Leaders Team


Produced in cooperation with:
Medical Logix, LLC



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Monday, January 11, 2016

CHAMPIONS TACKLING MS Gala - Request letter sponsor for business and or individuals



MS Views and News is a nonprofit 501c3 organization based out of South Florida which provides those affected by Multiple Sclerosis with access to live educational events, on-line education, resources and services to help improve the quality of life for those impacted by Multiple Sclerosis. To date MS Views and News has over 17,000 views on our YouTube Learning Channel, reaches 50,000  individuals through our e-newsletters, blogs and social media and educated over 3500 persons affected by Multiple Sclerosis in 2015. Since our first educational program in February 2010, MS Views and News has provided over 190 programs to this current date.

On April 9th, 2016 we will be hosting our Awards Gala titled “Champions Tackling MS” which will be honoring those who have made great impacts in the Multiple Sclerosis community. We anticipate over 150 guests from all of South Florida to attend this Gala. Additionally, the Awards Gala will be professionally photographed and video recorded.

Please consider becoming a “champion” by selecting a sponsorship and or advertising opportunity that you feel best would best represent you or your business in support of Multiple Sclerosis awareness, education and services. There are many appealing advertising opportunities that will be seen by many.  Your business name can be featured in different ways including; event signage, event brochure advertising opportunities, logo placement on tables and more.

Please review the accompanying Sponsorship Opportunity flyer to select your choice. We appreciate your support of MS Views and News and the Multiple Sclerosis community.

All proceeds from our Awards Gala helps maintain the programs and services that MS Views and News provides. With your support, we will continue leading in the effort to provide quality education, information and services for the Multiple Sclerosis community.

Sponsorship values begin at just $50.00

-- Click here please to see how you can help us, to help the
                             Multiple Sclerosis Community


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Sunday, January 10, 2016

Multiple sclerosis eye problems: Optic neuritis, nystagmus, and diplopia

Optic neuritis is a condition of blurry or hazy vision which only affects one eye. Eye pain or discomfort may occur in optic neuritis, more so when the eye moves. The cause of optic neuritis isn’t well understood and many cases are deemed idiopathic meaning no identifiable cause is found. In multiple sclerosis optic neuritis is common and is often the first symptom of MS. Infections, too, can lead to optic neuritis.
Common symptoms of optic neuritis are:
  • Vision loss in one eye – this is temporary and can last seven to 10 days
  • Periocular pain – when pain worsens when the eye moves
  • Dyschromatopsia – inability to see colors correctly
  • Photopsias – seeing flashing lights
  • Changes to how the pupil reacts to light
  • Uhthoff’s phenomenon – vision worsens with an increase in body temperature
Risk factors for optic neuritis include:
  • Being female between the ages 18 to 45
  • Having a diagnosis of multiple sclerosis
  • Living in a high latitude

Read More by clicking here


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Multiple sclerosis occurrence in women three to four times more likely than men

By: Emily Lunardo | Women's Health | Friday, January 08, 2016

Occurrence of multiple sclerosis in women is three to four times higher compared to men. Multiple sclerosis (MS) in women is usually diagnosed in their twenties or thirties. Because women have different health concerns than men, multiple sclerosis can lead to many complications in women including in regards to their menstrual cycles, contraception, menopause and pregnancy and birth.
Multiple sclerosis occurrence in women three to four times more likely than men
Multiple sclerosis symptoms can become worse during a woman’s menstrual cycle where they may feel loss of balance, depressed and especially fatigued. Multiple sclerosis does not affect fertility but if you choose to use an oral contraceptive it’s important to consider how it may or may not interact with other medications specific to multiple sclerosis. During menopause, similar to menstrual cycles, symptoms of multiple sclerosis may appear worse but it’s important to note that hormonal therapies can be used as directed by your doctor.

Steps to understand why men are better protected from MS than women

What began as an experiment gone wrong, when a graduate student used male mice instead of female mice for her experiment she unintentionally gave researchers insight as to why women are at a higher risk to develop multiple sclerosis compared to men.
Lead researcher Melissa Brown said, “When we induce the disease in this strain of female mice, virtually 100 percent of them get very sick. Male mice either get no disease or very little, so MS researchers typically use females in their studies.”

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7 HABITS TO ADOPT NOW TO EASE MULTIPLE SCLEROSIS (MS) FLARES LATER

Multiple sclerosis (MS) can be a sneaky disease: Symptoms that have been dormant for a long time can flare at any moment. “An MS flare is when the immune system attacks a region of the brain or spine,” says Peter Bergmann, MD, a neurologist with Kaiser Permanente Colorado in Denver.“There’s a multitude of possible symptoms, and they’re different for everyone. Some MS symptoms can last more than 24 hours — and sometimes even weeks.”
Common MS symptoms include impaired vision, loss of sensation, weakness, trouble thinking, and fatigue. While taking daily medications is essential, you can also practice certain healthy habits every day to better prepare yourself for an MS flare.

Exercise Every Day

Whether you play with your kids, walk, or run, regular exercise can help you prepare for an MS flare. “When you’re doing something healthy for your body,” Dr. Bergmann says, “you’re doing something healthy for your nervous system.” If you’re able to exercise, it will help your nervous system rewire after a flare. Combination exercises — such as strengthening, stretching, balancing, and aerobic moves — can reduce fatigue and other MS symptoms while improving quality of life, according to a study published in the Iranian Red Crescent Medical Journal in 2014.

Eat Healthy

There’s no special diet for MS, but it’s important to eat healthy foods. “A nutritious, well-balanced diet helps to control body weight, blood pressure, blood sugar, and more,” Bergmann says. “All of this helps people with MS function better.” The National Multiple Sclerosis Society recommends eating a high-fiber, low-fat diet and avoiding specific or fad diets because there’s no concrete research indicating that special diets benefit MS or reduce flares.

Reduce Stress

Stress management — such as deep breathing and other relaxation techniques — is an essential daily habit for staying healthy, says Bergmann. A review of research published in the journal Neurology Research International in 2014 found that 85 percent of MS flares may be related to stress and that new brain lesions may form after stressful events. Researchers also found that regular meditation improves MS symptoms, enhancing quality of life.


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