Please visit our MS learning channel on Youtube, which provides hundreds of topics from our education programs, that were video-recorded and archived here: www.youtube.com/msviewsandnews -- Be empowered with MS news by registering with us: www.register.msviewsandnews.org

joomla ecommerce template -- Scroll left side of this blog for needed resources. Also, use our 'search by topic' tool, to find specific information.

Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.

============================================================

Saturday, June 18, 2016

Trigeminal neuralgia: New classification and diagnostic grading for practice and research


                                                                  
  

Click here to receive MS news via e-mail


Review article
Cruccu G, et al. Neurology. 2016.

Abstract

Trigeminal neuralgia (TN) is an exemplary condition of neuropathic facial pain. However, formally classifying TN as neuropathic pain based on the grading system of the International Association for the Study of Pain is complicated by the requirement of objective signs confirming an underlying lesion or disease of the somatosensory system. The latest version of the International Classification of Headache Disorders created similar difficulties by abandoning the term symptomatic TN for manifestations caused by major neurologic disease, such as tumors or multiple sclerosis. These diagnostic challenges hinder the triage of TN patients for therapy and clinical trials, and hamper the design of treatment guidelines. In response to these shortcomings, we have developed a classification of TN that aligns with the nosology of other neurologic disorders and neuropathic pain. We propose 3 diagnostic categories. Classical TN requires demonstration of morphologic changes in the trigeminal nerve root from vascular compression. Secondary TN is due to an identifiable underlying neurologic disease. TN of unknown etiology is labeled idiopathic. Diagnostic certainty is graded possible when pain paroxysms occur in the distribution of the trigeminal nerve branches. Triggered paroxysms permit the designation of clinically established TN and probable neuropathic pain. Imaging and neurophysiologic tests that establish the etiology of classical or secondary TN determine definite neuropathic pain.
© 2016 American Academy of Neurology.






MS Views and News
Providing educational information, resources and services for those affected by MS





Learn about "Therapeutic inertia" which has been defined as the failure of health-care provider to initiate or intensify therapy when therapeutic goals are not reached


                                                                  
  

Click here to receive MS news via e-mail



 2014 Jul 2;15:130. doi: 10.1186/1471-2296-15-130.

Lebeau JP1Cadwallader JSAubin-Auger IMercier APasquet TRusch EHendrickx KVermeire E.

Abstract


BACKGROUND:
Therapeutic inertia has been defined as the failure of health-care provider to initiate or intensify therapy when therapeutic goals are not reached. It is regarded as a major cause of uncontrolled hypertension. The exploration of its causes and the interventions to reduce it are plagued by unclear conceptualizations and hypothesized mechanisms. We therefore systematically searched the literature for definitions and discussions on the concept of therapeutic inertia in hypertension in primary care, to try and form an operational definition.

METHODS:
A systematic review of all types of publications related to clinical inertia in hypertension was performed. Medline, EMbase, PsycInfo, the Cochrane library and databases, BDSP, CRD and NGC were searched from the start of their databases to June 2013. Articles were selected independently by two authors on the basis of their conceptual content, without other eligibility criteria or formal quality appraisal. Qualitative data were extracted independently by two teams of authors. Data were analyzed using a constant comparative qualitative method.

RESULTS:
The final selection included 89 articles. 112 codes were grouped in 4 categories: terms and definitions (semantics), "who" (physician, patient or system), "how and why" (mechanisms and reasons), and "appropriateness". Regarding each of these categories, a number of contradictory assertions were found, most of them relying on little or no empirical data. Overall, the limits of what should be considered as inertia were not clear. A number of authors insisted that what was considered deleterious inertia might in fact be appropriate care, depending on the situation.

CONCLUSIONS:

Our data analysis revealed a major lack of conceptualization of therapeutic inertia in hypertension and important discrepancies regarding its possible causes, mechanisms and outcomes. The concept should be split in two parts: appropriate inaction and inappropriate inertia. The development of consensual and operational definitions relying on empirical data and the exploration of the intimate mechanisms that underlie these behaviors are now needed.


Model of shared decision-making leading to either appropriate inaction or inappropriate inertia. click: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094689/figure/F2/


article source found here:
http://www.ncbi.nlm.nih.gov/pubmed/24989986 





Fostering effective Communications with your MS healthcare team - video with Ben Thrower, MD


                                                                  
  Click here to receive MS news via e-mail
        
 
May 3, 2016 from Atlanta, Ga,


With Dr. Ben Thrower, MD of Neurology








MS Views and News
Providing educational information, resources and services for those affected by MS


Be an Active Member of your MS Village while learning about the immune sytem


                                                                  
 

 Click here to receive MS news via e-mail
         
* Optimize and Expand your Village. 
* The MS Patient being the head of the Village
* Learn to take a more active role in your MS

* How people get MS
* Being a good listener
* Vitamins
* MS Risk Factors
* Remission vs. Relapse
* MRI * white spots * contrast * enhancing lesions * dark spots
* Progressive MS







Here is the form, that Dr. Boster refers-to, (at 17:01 into this video)


Listen to Dr. Boster speak about the immune system, the armies involved and the battles.


Watch this video then share with family and friends using social media or direct email

.
.


MS Views and News
Providing educational information, resources and services for those affected by MS





Resources and support for Veterans, children with pediatric MS, and African American and Hispanic/Latino individuals living with and affected by MS


                                                                  
  Click here to receive MS news via e-mail
        
 

Information acquired from the National MS Society website








MS Views and News
Providing educational information, resources and services for those affected by MS





Insurance & Financial Information


                                                                  
  Click here to receive MS news via e-mail
        
 


Whether you simply need to stay in financial shape, or you’re struggling financially as a result of MS, the National MS Society wants to help. This section provides information and resources to people with MS about staying financially secure by knowing how to take best advantage of your health coverage options and needs, by staying insured when circumstances change, and by planning for your future needs. 






MS Views and News
Providing educational information, resources and services for those affected by MS





Scooter Buyer's Guide


                                                                  
  Click here to receive MS news via e-mail
        
 

a publication of the National Multiple Sclerosis Society:

The Buyer’s Guide helps people in the process of purchasing a scooter with valuable questions to ask to make sure the equipment meets your needs. This guide is in PDF format and requires Adobe Acrobat Reader to view/print.

View Buyer’s Guide





MS Views and News
Providing educational information, resources and services for those affected by MS





Friday, June 17, 2016

Video Presentation - A discussion on tolerability, recognizing the invisible symptoms


                                                                  
  Click here to receive MS news via e-mail
        
 


 from Atlanta, Georgia - Tracy Walker FNP-C, WOCN, MSCN, provides discussion on adherence, tolerability, recognizing the invisible symptoms and how to effectively discuss issues with your healthcare provider

.
.

MS Views and News
Providing educational information, resources and services for those affected by MS





Myelination Relies on Mechanical Stimuli Like That Used for Bone Repair, Study Finds


                                                                  
  Click here to receive MS news via e-mail
        
June 14, 2016

Researchers at the University of Buffalo’s Hunter James Kelly Research Institute (HJKRI) discovered that the cells that form myelin in the nervous system respond to mechanical stimulation by activating molecules from a specific pathway, which are transferred to the nucleus, triggering myelination.
The findings, which may be key to developing new therapies for myelin diseases such as multiple sclerosis (MS), were published in the journal Nature Neuroscience, in the study “YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells.
“There were hints in previous studies that mechanical properties of tissues could influence the behavior of myelin-forming cells,” M. Laura Feltri, MD, the study’s senior author, a professor of biochemistry and neurology in the Jacobs School of Medicine and Biomedical Sciences at Buffalo and a researcher at HJKRI, said in a press release. “Our work proves for the first time, in vivo, that this is indeed the case. We have demonstrated that mechanical information is necessary for myelination to occur.”
Mechanical signaling is already accepted as a major factor in the injury and repair of muscles and bones. Putting weight on a broken bone is known to generate a mechanical force that improves the formation of new bone cells. “Now we know that a similar phenomenon is occurring with myelin cells,” she said.
The study also found that Yap and Taz, two proteins of the Hippo pathway known to be crucial for mechanical signal transduction by moving into the nucleus and regulating gene expression upon a mechanical stimuli, were involved in myelin formation. When mice were genetically engineered to lack these proteins, they showed symptoms of severe peripheral neuropathy, including atrophy, weakness, and tremor.
Such findings may pave the way for the development of new therapies for myelin-related disorders.



MS Views and News
Providing educational information, resources and services for those affected by MS





Processed Foods and Additives May Lead To MS, Autoimmune Diseases


                                                                  
  Click here to receive MS news via e-mail
        
 

Processed foods have been added to the list of “no-no” items that we are not supposed to eat if you, like me, are unfortunate enough to have MS. We were already warned against gluten, salt and various other ingredients in our diet; now it’s processed foods and additives.

This is because research says that additives commonly used in processed foods can cause damage to the intestinal tolerance and immunity balance. This appears to be a knock-on effect of the food additives seriously harming the tight junctions that protect the intestinal mucosa, also called the gastric mucosa, which is the lining of the gastrointestinal tract.

The immunity balance is important as it works to prevent multiple sclerosis and other autoimmune diseases.

As the incidence of autoimmune disease continues to rise around the world, according to a variety of authorities, so both processed food and food additive industries continue to grow.

Professor Aaron Lerner, of the Technion Faculty of Medicine and Carmel Medical Center, in Haifa, Israel, and a lead author of the study that led to this latest warning, said: “In recent decades there has been a decrease in incidence of infectious diseases but, at the same time, there has been an increase in the incidence of allergic diseases, cancer and autoimmune diseases.

“Since the weight of genetic changes is insignificant in such a short period, the scientific community is searching for the causes at the environmental level,” he said.

Avoid Processed Foods

The result of the study: “Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease,” was published in the journal Autoimmunity Reviews.


Continue reading




MS Views and News






Thursday, June 16, 2016

Educating Physicians and Scientists about Regenerative Medicine


                                                                  
  Click here to receive MS news via e-mail
        
 


This is an interview with Joseph Krieger, President of Boston Biolife. Boston BioLife is an innovative organization that presents workshops for physicians and scientists to educate them about novel advances in regenerative medicine. Its training programs are characterized by using both didactic and interactive, “hands-on” approaches, which physicians can get ACCME accreditation for attending. Its next event will be “Hands–On Stem Cell Therapies and Biologics for the Clinical Application of Pain Management” in Boston on July 16-17, 2016.





MS Views and News
Providing educational information, resources and services for those affected by MS





Stem Cell Therapy Shows Promise for Treatment of MS – Q&A with Dr. Sadiq of the Tisch MS Research Center of NY


                                                                  
  Click here to receive MS news via e-mail
        


In breaking news released January 13th, 2016, Dr. Sadiq announced that the Tisch MS Research Center of New York will be pursuing a Phase II clinical trial exploring the use of stem cells in the treatment of MS.1 The announcement followed positive results from a FDA-approved Phase I stem cell trial. In this Phase I trial, MS patients received multiple spinal injections of neural progenitors derived from bone marrow mesenchymal stem cells (called MSC-NPs).


Compellingly, it was the first time ever that a treatment method has demonstrated reversal of established disability in MS patients.

For more than 20 years, Dr. Saud Sadiq has aimed to merge clinical excellence with innovative research targeted at finding the cure for multiple sclerosis. Today, the Tisch MS Research Center of New York, a non-profit research center, has a close relationship with its affiliated clinical practice, the International Multiple Sclerosis Management Practice. This partnership enables the testing of new MS treatments and accelerates the pace at which research discoveries are translated into clinical practice, as demonstrated by the center’s innovative work with use of neural progenitors derived from bone marrow mesenchymal stem cells.

Enjoy the question and answer interview with Dr. Sadiq below to learn about recent progress with the use of stem cell therapy to reverse disability in MS patients and Tisch MSRCNY’s need for funding to facilitate research aimed at finding a cure for MS, an outcome that would change the lives of the 400,000 people in the U.S. and about 2.5 million people worldwide who are affected by the disease.

READ MORE


MS Views and News
Providing educational information, resources and services for those affected by MS