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Monday, January 23, 2017

MS Patients with Spasticity Needed for Study of Extended-release Baclofen Capsules


                                                                  
  

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A new clinical trial evaluating the effectiveness of extended-release baclofen capsules in relieving spasticity related to multiple sclerosis (MS) is calling for 135 people with any form of the disease. The study, taking place in six U.S. states, is sponsored by Sun Pharma, the drug’s developer.
Baclofen, an approved MS treatment available in different forms, acts as a muscle relaxer and an antispastic agent. As an extended-release treatment, Baclofen GRS distributes the drug’s active ingredients over time in a patient’s body, possibly allowing for less frequent dosing than is now common.
Spasticity refers to feelings of stiffness, and a wide range of involuntary muscle spasms, and is one of the more common symptoms of MS, according to the National Multiple Sclerosis Society, which spotlights this study on its website.
To take part, patients must be 18 or older and diagnosed with any form of MS, have a known history of spasticity, and may already be using baclofen in its current approved formulations.
Participants should have no clinical history of hypersensitivity to baclofen and no previously treatment with intrathecal baclofen, a method that delivers the drug directly to the intrathecal space (area of the spine) via a surgically implanted infusion pump and catheter.




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