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Friday, March 31, 2017

Aaron Boster, MD Discusses How OCRELIZUMAB works in MS


Dr.Boster explains how OCRELIZUMAB works in #MS

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Anonymous said...

So if this new medicine is so good, why do I want to use Rebif any more? If it's the same cost, and it's better, I would rather have two IV treatments. Aren't rebif et al. about the same cost?

Look at this comparison of costs:

Anonymous said...

You would want to stay on Rebif, as I am going to stay on Copaxone, because Rebif and Copaxone have been proven to be effective if they are used as directed and have less dangerous side effects than Ocrevus (ocrelizumab).

Anonymous said...

Rebif, Copaxone and Avonex are much much older medications and are not as effective (in general) in slowing progression. ALL medications have risks -- Rebif/Copaxone/Avonex can cause liver problems. Yes, the new drugs have more "risks" - but those that are on them (Tysabri for example) are monitored much more closely then those that are on the injectibles. I have had MS since 1996 officially -- Rebif/Copaxone/Avonex did absolutely nothing to slow progression. I was relapsing every 3 months for nearly 10 yrs. It wasn't until I started Tysabri in Jan 2010 that within 6 months my MS was actually in remission. I've only had 1 mild relapse in a little over 7 yrs. It all comes down to how much risk you are willing to undertake, how agressive your MS is. Since MS has taken much from me -- I choose quality of life -- the newer medicines give quality of life back to many of us.

Anonymous said...

So, if Tysabri disables your T cells and that puts you at a higher risk of PML because the T cells can't fight off the JCV then disabling or killing off the B cells (with ocrelizumab) will not allow the T cells to be charged to enable them to fight off JCV and therefore put you at higher risk for PML?