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Wednesday, June 7, 2017

Depression and Anxiety Under-diagnosed in MS

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Int J MS Care; ePub 2017 May 18; Marrie, et al
June 6, 2017

Depression and, to a greater extent, anxiety remain underdiagnosed and undertreated in multiple sclerosis (MS), according to a recent study, and both substantially contribute to reduced health-related quality of life (HRQOL) in MS. Researchers linked clinical and administrative data for 859 participants with MS; HRQOL was measured by the Health Utilities Index (Mark III). They classified participants as depressed or anxious using administrative data, self-reported physician diagnoses, and the Hospital Anxiety and Depression Scale (HADS). They found:
  • Lifetime prevalence estimates for depression were approximately 30% regardless of methods used, but 35.8% with current depressive symptoms were not captured by either method.
  • Prevalence estimates of anxiety ranged from 11% to 19%, but 65.6% with current anxiety were not captured by either method.
  • Prior diagnoses did not decrease HRQOL after accounting for current symptoms.

Marrie RA, Patten SB, Berrigan LI, et al. Diagnoses of depression and anxiety versus current symptoms and quality of life in multiple sclerosis. [Published online ahead of print May 18, 2017]. Int J MS Care. doi:10.7224/1537-2073.2016-110.

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