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Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, for your personal knowledge and to keep you informed of current health-related issues. It is not a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.


Friday, December 12, 2008

Novartis’s Multiple Sclerosis Drug (FTY720) Cuts Relapse Rates

A Bloomberg Report

Novartis’s Multiple Sclerosis Drug Cuts Relapse Rates (Update1)

By Dermot Doherty and Naomi Kresge

Dec. 12 (Bloomberg) -- Novartis AG, Switzerland’s second- biggest drugmaker, said its experimental oral treatment FTY720 kept multiple sclerosis at bay in a study.

The medicine cut annualized relapse rates by 38 to 52 percent in the study, depending on the dose, compared with treatment with Biogen Idec Inc.’s interferon therapy Avonex, the Basel, Switzerland-based company said today.

The compound was “generally well-tolerated” and the side effects were in line with previous trials, Novartis said. Seven patients in the study were diagnosed with skin cancer in the FTY720 group, compared with one patient in the interferon group. All the skin cancers were successfully removed, the Swiss company said. Novartis already reported two fatal herpes infections in patients being treated with its drug, which suppresses the immune system.

“The safety profile of FTY720 has been a primary concern for investors, and over time more and more safety issues have shown up,” Tim Anderson, an analyst for Sanford C. Bernstein & Co., wrote in a note to investors. “It is important to realize, however, that all currently available MS drugs have significant side effects.”

Novartis fell as much as 3 percent to 53.5 Swiss francs in Swiss trading. The stock declined 60 centimes, or 1.1 percent, to 54.55 francs at 11:54 a.m.

The Swiss drugmaker said it will release full results at a major scientific conference in 2009. The company plans to ask regulators in Europe and the U.S. by the end of 2009 to approve FTY720, potentially the first oral pill for multiple sclerosis.

To contact the reporter on this story: Dermot Doherty in Geneva at ddoherty9@bloomberg.net

Last Updated: December 12, 2008 06:01 EST

Suggestions, Comments and/or Questions are always appreciated.. - Thank you

Take some time for yourself and relax

Provided by Joe in Florida:

This holiday season, MS LifeLines® wants to remind you to take some time for yourself and relax!

Amidst the hustle and bustle of the season, it's important to try to schedule some downtime for yourself. Even finding twenty minutes in a day to unwind and relax can go a long way to relieving tension and recharging your batteries.

MS LifeLines Ambassador Teresa knows how important it is to relax. Whether it's crocheting, reading, doing crossword puzzles or watching her favorite television game show, Teresa knows that relaxing is an important part of her day that also delivers real health benefits. "I love doing word puzzles because they help me unwind and keep my mind sharp."

Relaxing can provide lots of health and wellness benefits, including helping you have better sleep, a decrease in tension and more energy. And there are many, many ways to relax. For instance, reading is a wonderful way to exercise your mind and escape from the day-to-day. If reading is difficult on your eyes, find books with larger print or books on tape or CD, all of which are available at most local libraries.

Learn about how different activities like exercising, meditation, and laughing can help you relax!

Suggestions, Comments and/or Questions are always appreciated.. - Thank you

Thursday, December 11, 2008

MRI Can Spot Presymptomatic MS

HealthDay News

A third of patients with suspect scans develop the disease within 5 years, study finds

Posted December 10, 2008

WEDNESDAY, Dec. 10 (HealthDay News) -- Among people whose brain scans show signs of multiple sclerosis but who have no symptoms, one-third will develop MS within about five years, researchers say.

The study included 44 people who had MRI brain scans for a variety of reasons, including migraines or head trauma. The scans detected abnormalities similar to those that occur in MS. After the researchers confirmed these abnormalities were MS-related and ruled out other causes, they followed the patients for a number of years to find out if they developed the disease.

Suggestions, Comments and/or Questions are always appreciated.. - Thank you

Wednesday, December 10, 2008

MS Research Studies underway at: Neurological Associates Research

Research Ctr information found below the listing of:


  • Relapsing-Remitting MS - A 24 month study comparing the efficacy and safety of 2 different doses of oral Fingolimod versus placebo with an optional extension phase. For more information visit: www.msclinicaltrials.com.

  • Relapsing- Remitting MS - A 4 year study to compare 2 annual cycles of intravenous low and high dose alemtuzumab(Campath) to three times weekly subcutaneous Rebif in patients who have relapsed on therapy. For more information visit: : www.clinicaltrials.gov/ct2/show/NCT00548405

  • Relapsing-Remitting MS - A 2 year study comparing safety and efficacy of 2 different doses of oral Fumarate versus placebo with Copaxone as an active comparator. For more information visit: www.clinicaltrials.gov/ct/show/NCT00451451.

  • Relapsing Remitting MS - an 85 day study to assess safety and efficacy of 2 oral doses of Dextromethorphan/Quinidine in the treatment of Pseudobulbar Affect (inappropriate laughter/crying) with an optional extension phase. For more information visit: www.pbatrial.com.

  • Relapse-Remitting MS- A 2 year study comparing safety and efficacy of 2 cycles of Alemtuzumab (Campath) intravenous Versus 3 times weekly subcutaneous Interferon Beta-1a (Rebif).

Learn More of the above studies by contacting the office of: Neurological Associates Research (Dr. Brian Steingo)
>>>>> Click here to review contact information


Large Study of Oral Laquinimod Seeking People with Relapsing-Remitting MS

Large Study of Oral Laquinimod Seeking People with Relapsing-Remitting MS

To learn more of ORAL LAQUINIMOD,

click here to review info ad found on the MS Views and Related News website

>> click here to review the Teva Clinical Trial Ad.

There are two Laquinimod Clinical Trials.
Allegro, which is now closed to enrollment (that sought 1000 patients) and Bravo, whose enrollment is still open and seeking 1200 patients.
...,,, Click here to review the Bravo Clinical Trial Information


Rationale: Multiple sclerosis occurs when the immune system mistakenly attacks nerve fiber-insulating myelin and other brain and spinal cord tissues. Laquinimod is believed to affect this attack. Oral laquinimod (Teva Pharmaceutical Industries) reduced disease activity by 40.4% compared with inactive placebo in a phase 2 study of 306 people with relapsing-remitting MS. (Lancet 2008; 371: 2085–92) A phase 3 study of laquinimod versus inactive placebo is currently underway in 1000 people with relapsing-remitting MS.


Great Strides Moved MS Research Forward During 2008

Dec 02, 2008

The year saw rapid research progress in virtually every field of science and medicine that impacts our understanding of the unpredictable neurological disease of multiple sclerosis. Thanks to its generous contributors, in 2008 the National MS Society invested nearly $50 million to support over 440 new and ongoing MS research projects as part of its international effort to prevent, treat and cure MS.

Significant advances have been made in both clinical and laboratory studies in MS. In addition, more than 130 clinical trials are underway around the world – with over one dozen final-phase trials of new therapies including some taken by mouth. Key highlights of the last year include:

To Read Balance of this article from the Nat'l MS Society, Click Here

Return to this page if you want to leave a comment. Thank You

What is pseudobulbar affect (PBA)?

What is pseudobulbar affect (PBA)?
PBA is a condition characterized by episodes of uncontrollable laughing and/or crying that may be inappropriate, unrelated to the situation at hand, or not expressing the person's mood. The condition is known by other terms, including emotional lability, emotional incontinence, and pathological laughing and crying.

PBA is associated with neurologic disorders that may include, but are not limited to multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), dementias including Alzheimer's disease, Parkinson's disease, stroke, and traumatic brain injury.

How many people live with PBA?
A significant percentage of patients with neurologic disorders also suffer from PBA - estimates of frequency range from 10 percent to 50 percent. More than one million people may suffer from PBA in the United States alone.

Suggestions, Comments and/or Questions are always appreciated..
- Thank you


How Schwann Cells Might Be Altered So That They Might Be Better Candidates For Myelin Transplantation

From the Myelin Project:

How Schwann Cells Might Be Altered So That They Might Be Better Candidates For Myelin Transplantation
Author: Anne Baron-Evercooren, PhD
Release Date: Wednesday 10-Dec-08 2:00 PM
Dr. Anne Baron-Evercooren, Centre Hospitalier Universitaire, Pitié-Salpêtrière, Paris, presented her investigation of how Schwann cells might be altered so that they might be better candidates for myelin transplantation. By forcing the cells to express an enzyme, sialyltransferase, their ability to migrate was greatly improved. Schwann cells (SC) form myelin in the peripheral nerves and are easy to get. Despite their obvious repair potential in the central nervous system (CNS),... [More Info]

Suggestions, Comments and/or Questions are always appreciated.. - Thank you

How Can the "MS Hug" be Managed?

info obtained from ms.abouts.com

The "MS Hug" is an annoying and often painful MS symptom. If the symptom is severe enough to cause discomfort breathing, your neurologist may define this as a true relapse, run an MRI and give a course of Solu-Medrol. There are also several medications which can be prescribed that can provide varying degrees of relief (see below).

The following suggestions have been taken from different patient accounts of what helps them – different things may work for you at different times:

Deep Breathing Exercises: Breathe in as deeply as you can (really engaging the diaphragm) through your nose and blow out through your mouth.

Apply Pressure: Place the flat of your hand on the area and press fairly hard. I have even heard of people wrapping themselves in Ace bandages for the same effect.

IF YOU Suffer from the MS Hug, please tell others what you do to manage this symptom.
Leave your comment here. - Thank you


Help the Obama Administration Frame Comprehensive Health Care Reform More Info

As the Obama Administration and the 111th Congress prepare to convene, we have an early opportunity to make an impact on the discussion around comprehensive health care reform.

President-elect Barack Obama recently sent out a call to action for all Americans. The incoming Administration wants you to engage your family and friends in a dialogue about comprehensive health care reform.

» Read More



Misc. Info: If you want to reduce the amount of SPAM you are receiving...

Information provided by Susan in Miami

AND IT IS TRUE --- If you want to reduce the amount of SPAM you are receiving, stop doing what is mentioned below

In case you are unaware:
Forwarded to me today:
Here is a nice little tidbit of information that came my way this morning. So if any of you are wondering why I didn't return something to you that said something like "if I don't get this back, I'll". . . or "See how many flowers you can get back," or "Forward this to 10 people in the next 5 mins. or something bad will happen to you," etc.

The following is why I don't send them back.

ADVICE from Snopes.com

1) Any time you see an email that tells you to forward this on to '10' of your friends, or sign this petition or you'll get bad luck, good luck, or whatever, it almost always has an email tracker program attached that tracks the cookies and emails of those folks you forward to.

The host sender is getting a copy each time it gets forwarded, and then is able to get lists of "active" emails to use in spam emails, or sell to other spammers.

2) Almost all emails that ask you to add your name and forward on to others are similar to that mass letter years ago that asked people to send business cards to the little kid in Florida who wanted to break the Guinness Book of Records for the most cards.

All it is, and all any of this type of email is, is a way to get names and "cookie" tracking information for telemarketers and spammers - - to validate active email accounts for their own profitable purposes.

You can do your friends and family members a GREAT favor (PLEASE) by sending this information to them. You will be providing a service to your friends, and will be rewarded by not getting thousands of spam emails in the future!

If you have been sending out (forwarding) the above kinds of emails, now you know why you get so much spam!

Do yourself a favor and STOP adding your name to those types of listings regardless how inviting they might sound! You may think you are supporting a GREAT cause, but you are NOT in the long run. Instead, you will be getting tons of junk mail later! Plus, you are helping the spammers get rich! Let's not make it easy for them!

Also, email petitions are NOT acceptable to Congress or any other organization. To be acceptable, petitions must have a signed signature and the full address of the person signing the petition.

Read the full story here:


Tuesday, December 9, 2008

UK MS Society calls for law change on unproven stem cell trials

Info obtained from the MSIF.

UK MS Society calls for law change on unproven stem cell trials
Following the recent guidelines on unproven stem cell treatments by the International Society for Stem Cell Research (ISSCR), the UK MS Society is calling on the UK government to change the law on advertising medicines.

The MS Society supports the advice from the ISSCR that patients and their families should approach stem cell therapy with caution. To read more click here.

ISSCR: patient handbook on stem cell therapies

Source: UK MS Society

Suggestions, Comments and/or Questions are always appreciated.. - Thank you

MRI in the diagnosis of pediatric multiple sclerosis

Neurology. 2008 Nov 26. [Epub ahead of print]

Summary: MRI diagnostic criteria have not yet been adopted for MS in children. The authors looked for differences in MRI features of MS and other demyelinating diseases and proposed some modifications to the current criteria for adults.

BACKGROUND: MRI diagnostic criteria have not yet been adopted for pediatric multiple sclerosis (MS). MRI plays a pivotal role in supporting the diagnosis of MS in adults. We sought to quantitatively define the MRI features of pediatric MS, to determine features that distinguish MS from nondemyelinating relapsing childhood neurologic disorders, and to propose MRI criteria for lesion dissemination in space in children with MS.

» Read More

Suggestions, Comments and/or Questions are always appreciated.. - Thank you

Role of MRI in the differentiation of ADEM from MS in children

Neurology. 2008 Nov 26. [Epub ahead of print]

Summary: ADEM is a disease which can present in a similar way to a first attack of MS, particularly in children. This study showed some differences in the MRI patterns between them that may be useful to distinguish them.

BACKGROUND: Acute disseminated encephalomyelitis (ADEM) is typically a monophasic demyelinating disorder. However, a clinical presentation consistent with ADEM can also be the first manifestation of multiple sclerosis (MS), particularly in children. Quantitative analyses of MRI images from children with monophasic ADEM have yet to be compared with those from children with MS, and MRI criteria capable of distinguishing ADEM from MS at onset have yet to be derived.

» Read More

Comments and/or Questions are always appreciated.. - Thank you

Observation: Natalizumab Use in Pediatric Multiple Sclerosis

Vol. 65 No. 12, December 2008

Archives of Neurology

Peter Huppke, MD; Wiebke Stark, MD; Claudia Zürcher, MD; Brenda Huppke, MD; Wolfgang Brück, MD; Jutta Gärtner, MD

Arch Neurol. 2008;65(12):1655-1658.

Background: Natalizumab, a humanized monoclonal antibody raised against 4 integrins, is approved for treatment of active relapsing-remitting multiple sclerosis (RRMS) in adult patients.

Objective: To determine the safety, effectiveness, and tolerability of natalizumab use in pediatric patients with MS.

Design: Case report.

» Read More Please Return to this page to Leave your Comments


Monday, December 8, 2008

Welcome To Education & Resources for Stem Cell Therapy


1] To Help Readers understand why Adult Stem Cell therapy (aka 'Repair' Stem Cell therapy) does NOT have controversial moral & ethical issues, contrary to embryonic stem cell research ~ please take time to read & learn how the most promising stem cell research & treatment does NOT require destruction of human embryos.

2] To Form a Community among:
~ Potential Adult Stem Cell Therapy Patients
~ Previous Adult Stem Cell Therapy Patients
~ Benefactors to Adult Stem Cell Therapy Patients
~ Family & Friends of Loved Ones w/ a Dreaded Disease
~ Caregivers
~ Medical Professionals
~ Research Students
~ Sign-Up Today to Show Unity in the Universal Hope for Healing

About some of this websites' content:
Due to the broad spectrum of potential, all natures of repair stem cell therapies will be broached here to help readers become better informed of distinctions between current & proposed embryonic stem cell research debates vs. available & proven Adult Stem Cell Therapy treatments.

The long-term focus of this site continues to be on the advancements of Adult Stem Cell Therapy ~ what it can do ~ where it can be found ~ how it can be be obtained.

Comments and/or Questions are always appreciated.. - Thank you

Sunday, December 7, 2008

Multiple Sclerosis News from the MS News Channel

Timothy L. Vollmer, MD

Department of Neurology
University of Colorado Health Sciences Center
Co-Director of the RMMSC at Anschutz Medical Center
Medical Director-Rocky Mountain MS Center
My Educational Video on MS and MS Trials
Produced by www.MSNewsChannel.com
Suggestions, Comments and/or Questions are always appreciated.. - Thank you

A Stem Cell therapy update from Preston Walker

From: Preston Walker [mailto:pwalker2644@sbcglobal.net]
Sent: Sunday, December 07, 2008 3:28 PM
Subject: Interview before/after treatment in Costa Rica

As most of you know, I have had Multiple Sclerosis since December of 2001. I pursued stem cell treatment in Costa Rica in May 2008. I can absolutely say that pursuing the treatment was the best decision I have made. For now, I am MS symptom free. I can't/won't say I have been cured for quite some time now but the treatment was worth every moment working extra to pay for the treatment and praying the funds would come in through the fund raisers.

The company offering the treatment there is the Institute for Cellular Medicine. The long and short of it is that my entry and exit interview has been posted on YouTube. Through these sort of videos and exposure, I know the company is going to make a lot of money but I also know spreading the word of the treatment is providing a lot of hope through the MS Community.

If you want to watch the video, go to YouTube and search the site for me. There I am!!

I hope this finds everyone doing well,
Preston Walker

Suggestions, Comments and/or Questions are always appreciated.. - Thank you

In Response to The Headache Posting, found just below

Guillermo, from the Dominican Republic has offered the following information with regards to headaches and MS:

Hi Stuart:
I've read on your blog that you want more investigations about headaches and MS.
I think this will help you.

I suffered from an everyday terrible migraine-like headache . Everyday I took 6 or 8 tylenols for about 6 months, with success only until the effects of the tylenols.
I didn't tolerate noise, odors or anything.

One day I was reading on the internet about calcium, and between one page and another I read that calcium orotate helps people with lupus and MS. And when I was reading the article, it said that people with MS should follow the same protocol of people with lupus, but those who suffer from a migraine like headache should take a higher dose.

I immediately order this calcium to see if it can help me, and with the 1st tablet, the headache disappeared.
That was 6 years ago, and that headache hasn't appeared again.
I take 1-745mg in the morning with an empty stomach, and 1-745mg with dinner.
I have made some tests to see if it's real, quitting the calcium for a couple of days, and the headache came back.

I recommended this calcium to 3 friendS with MS and the headache, and all of them are headache free.

Here's the part of the article where talks about it:

Around 1975 Dr. Nieper began treating lupus erythematosus patients with calcium orotate. 35 He found that a dose of 1 to 2.5 grams was surprisingly effective when administered over a period of at least one year, even in advanced cases with pulmonary constriction, pleural effusions, or cardiomyopathy. 35, 50 Therapy also involved low-dose prednisone and a variety of nutrients to promote adrenal steroid synthesis, such as selenium and vitamins C and D2, as well as other calcium and magnesium salts. An account of one patient’s successful response to therapy with calcium orotate and other Nieper compounds can be found in an article available from the Brewer Science Library. 51 In addition Nieper found that multiple sclerosis sometimes accompanies lupus, so it’s not surprising that his protocol for treating MS is strikingly similar to that for treating lupus. 52, 53 He recommended a dose of 1 gram calcium orotate per day for MS patients, with a higher dose given to those patients with a tendency toward migraine-like headaches.

The complete article is:



Suggestions, Comments and/or Questions are always appreciated.. - Thank you

Multiple sclerosis seen associated with headache

Yahoo News
Reuters - Wed Dec 3, 3:31 pm ET

(Stuart will insist that more needs to be known of Headaches and MS, as he has battled almost daily headaches for more than 10 years)

NEW YORK (Reuters Health) – Patients with multiple sclerosis are more apt to suffer from headaches than the general population, results of a study hint.

Multiple sclerosis, or MS, is a disease in which the immune system mistakenly attacks and damages the myelin sheath that protects nerve cells. It can cause symptoms ranging from vague tingling to blindness and paralysis.

"Headache is not generally considered a symptom of MS, and studies investigating the relationship between the two conditions have produced conflicting results," Dr. Mario Zappia, of the University of Catania, and colleagues note in a report published this month.

» Read More

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Beware of Bogus Clinics Offering Stem Cell Cures

Discover Magazine

Clinics around the world are offering unproven stem cell treatments to desperate patients with diseases like Parkinson’s and multiple sclerosis, a new report says, and consumers should be on the lookout for snake oil salesmen. A new set of guidelines issued by the International Society for Stem Cell Research (ISSCR) gives consumers some hints on how to identify the scammers: Beware, it warns, of clinics claiming to treat multiple diseases with the same cells, boasting that there is no risk, and offering patient testimonials - rather than results from clinical research - as evidence that their treatment works. “Patients want to believe so much that a treatment is helping them that they can convince themselves that is has” [New Scientist], the guidelines caution.

» Read More ( Come back to this page to leave your comments )


re: Progressive MS

Information obtained from the MS News Channel

Saturday, December 6

Long Term Outcomes of Autologous Hematopoietic Stem Cell Transplantation in Progressive Multiple Sclerosis

Progressive multiple sclerosis (MS) is going with continuously disability and unresponsive to high dose steroid and immunomodulation. The autologous hematopoietic stem cell transplantation (ASCT) has been introduced in treatment of the forms of multiple sclerosis.

Click: Blood (ASH Annual Meeting Abstracts) 2008 112: Abstract 4438
Suggestions, Comments and/or Questions are always appreciated.. - Thank you