Correlations of Perceived Deficits Questionnaire of Multiple Sclerosis Quality of Life Inventory with Beck Depression Inventory and neuropsychological tests

Jesus Lovera, MD, MSPH;1-2* Bridget Bagert, MD, MPH;3 Kyle H. Smoot, MD;2 Katherine Wild, PhD;2 Rachel Frank, BA;2 Kristin Bogardus, BS;2 Barry S. Oken, MD;2 Ruth H. Whitham, MD;1-2 Dennis N. Bourdette, MD1-2

1Multiple Sclerosis Center of Excellence West, Portland Department of Veterans Affairs (VA) Medical Center,
Portland, OR; 2Department of Neurology, Oregon Health & Science University School of Medicine, Portland, OR; 3Department of Environmental Health, Harvard School of Public Health, Cambridge, MA

Patients with multiple sclerosis (MS) can experience deterioration in their quality of life (QOL) in physical, cognitive, and emotional domains. Instruments that measure the impact of MS in health-related QOL have been developed to capture the impact of the disease on other domains besides physical disability. The prevalence of cognitive dysfunction in people with MS has been estimated to be between 45 and 65 percent [1-2].

Cognitive impairment in people with MS is associated with decreased employment and social interactions [3].

Instruments for measuring QOL in MS should include useful scales that measure the impact of cognitive impairment. The MS QOL Inventory (MSQLI) is a modular MS-specific health-related QOL instrument consisting of a widely used generic measure, the 36-item short form Medical Outcomes Study Health Status Questionnaire that is supplemented by nine symptom-specific measures [4].

» Read More