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Friday, January 18, 2013
Thursday, January 17, 2013
ELAN is looking for approval to sell the drug Tysabri to more multiple sclerosis sufferers.
Wednesday, January 16, 2013
Walking (Gait), Balance, & Coordination Problems
Dizziness and Vertigo
Respiration / Breathing Problems
SOURCE: National MS Society
Tuesday, January 15, 2013
on January 14, 2013 at 4:30 PM
Whether in society or nature, decisions are often the result of complex interactions between many factors. Because of this it is usually difficult to determine how much weight the different factors have in making a final decision. Neuroscientists face a similar problem since decisions made by the brain always involve many neurons. Working in collaboration, the University of Tübingen and the Max Planck Institute for Biological Cybernetics, supported within the framework of the Bernstein Network, researchers lead by CIN professor Matthias Bethge have now shown how the weight of individual neurons in the decision-making process can be reconstructed despite interdependencies between the neurons.
When we see a person on the other side of the street who looks like an old friend, the informational input enters the brain via many sensory neurons. But which of these neurons are crucial in passing on the relevant information to higher brain areas, which will decide who the person is and whether to wave and say 'hello'? A research group lead by Matthias Bethge has now developed an equation that allows them to calculate to what degree a given individual sensory neuron is involved in the decision process.
To approach this question, researchers have so far considered the information about the final decision that an individual sensory neuron carries. Just as an individual is considered suspicious if he or she is found to have insider information about a crime, those sensory neurons whose activity contains information about the eventual decision are presumed to have played a role in reaching the final decision. The problem with this approach is that neurons – much like people – are constantly communicating with each other. A neuron which itself is not involved in the decision may simply have received this information from a neighboring neuron and "joined in" the conversation. Actually, the neighboring cell sends out the crucial signal transmitted to the higher decision areas in the brain.
The new formula that has been developed by scientists addresses this by accounting not just for the information in the activity of any one neuron but also for the communication that takes place between them. This formula will now be used to determine whether only a few neurons that carry a lot of information are involved in the brain's decision process, or whether the information contained in very many neurons gets combined. In particular, it will be possible to address the more fundamental question: In which decisions does the brain use information in an optimal way, and for which decisions is its processing suboptimal?
Read more at: http://medicalxpress.com/news/2013-01-neuroscientists-decision-making-neurons.html#jCp
Monday, January 14, 2013
JANUARY 14, 2013
Scientists in recent years have found a way to infuse stem cells into the brains of animals to repair damage to the central nervous system, offering some of the most encouraging news yet for multiple sclerosis patients.
Now, a key $12.1 million study soon will be under way in Buffalo and two other upstate medical centers that will for the first time begin to test the procedure in people.
The hope is that the stem cells will generate new myelin, the fatty substance that surrounds nerves like the insulation on a wire. Myelin is damaged in MS, leading to weak or lost signals between nerves. Eventually, the painful disease spreads in a slow, unpredictable path toward paralysis.
“This is a promising strategy. It has been extraordinarily effective in mice, and there is great hope the technique will be successful in people,” said Dr. Steven Goldman, co-principal investigator and co-director of the University of Rochester Center for Translational Neuromedicine.
The study by researchers in Rochester, the University at Buffalo and Upstate Medical University in Syracuse has far-ranging implications. It potentially could be applied to millions of patients with a host of other conditions, including Alzheimer’s and Parkinson’s disease.
Although stem cells show great promise, the approach is a ways from reality.
What works in mice does not always work in humans. In addition, scientists don’t know what causes MS, so they can’t exactly replicate MS in animals, complicating tests of the potential new treatment.
“Expectations have to be kept under control. You’re not going to implant stem cells in people and suddenly see them running around,” said Dr. Bianca Guttman-Weinstock, co-principal investigator at UB.
Stem cells are often referred to as master cells because they develop into the many different types of cells in the body that form organs and tissue. Stem cells also have the potential to repair or replace damaged cells.
Other scientists are looking at whether it may be possible to use certain stem cells to prevent the body’s immune system from attacking nerves.
“There is a lot happening in stem cell research, and it’s exciting because five years ago, these were just ideas. Now, they are reality,” said Dr. Timothy Coetzee, chief research officer at the National MS Society.
Until recently, scientists didn’t know exactly which master stem cells ultimately developed into cells that make myelin in a complicated process. They now know that cells called oligodendrocytes produce myelin. They also learned how to turn stem cells into a type of cell called glial progenitor cells. Glial progenitor cells are the cells that make oligodendrocytes.
Sunday, January 13, 2013
re: a Stem Cell Therapy
Watch and Listen to this report
of Nan Luke - an MS patient Advocate
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Hear of the Fatigue and the Friction within the marriage, and the concerns.
Then after his introduction to Nancy Davis, watch Her video of "Lean on Me" - found here:
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