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Wednesday, October 1, 2014

Pilot Study Finds Stem Cell Treatment Safe for MS Patients

Source: MSFYI newsletter - August 2014

Researchers found that stem cell transplantation may be safe and feasible for MS patients. Using stem cells harvested from the bone marrow of the test subjects, the Phase I study suggests that the procedure deserves further study.

Following up on prior studies that found that stem cells were safe and effective in the treatment of other diseases, 24 participants with relapsing forms of MS were involved in a study that tested the use of bone-marrow-derived, culture-expanded Mesenchymal stem cells (MSCs). Led by Dr. Jeffrey Cohen of the Cleveland Clinic, researchers injected 16 women and eight men – 10 with relapsing-remitting and 14 with secondary-progressive MS – with MSCs and found that cell infusion was well-tolerated, and there were no treatment-related severe or serious adverse events.

While neither disease activation nor significant improvement was observed, researchers said that future trials to assess efficacy more definitively are warranted.

Cohen’s research was presented at the ACTRIMS-ECTRIMS MS Boston 2014.

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