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Wednesday, October 1, 2014
Pilot Study Finds Stem Cell Treatment Safe for MS Patients
Source: MSFYI newsletter - August 2014
Researchers found that
stem cell transplantation may be safe and feasible for MS patients. Using stem
cells harvested from the bone marrow of the test subjects, the Phase I study
suggests that the procedure deserves further study.
Following up on prior
studies that found that stem cells were safe and effective in the treatment of
other diseases, 24 participants with relapsing forms of MS were involved in a
study that tested the use of bone-marrow-derived, culture-expanded Mesenchymal
stem cells (MSCs). Led by Dr. Jeffrey Cohen of the Cleveland Clinic,
researchers injected 16 women and eight men – 10 with relapsing-remitting and
14 with secondary-progressive MS – with MSCs and found that cell infusion was
well-tolerated, and there were no treatment-related severe or serious adverse
While neither disease
activation nor significant improvement was observed, researchers said that
future trials to assess efficacy more definitively are warranted.
Cohen’s research was
presented at the ACTRIMS-ECTRIMS MS Boston 2014.