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Tuesday, November 18, 2014
Researchers Find Link Between MS, Eye Disease
A retrospective study shows that almost 60 percent of patients with both uveitis and MS are diagnosed with each within five years. This is the first study to provide a detailed description of the relative onset of uveitis and MS and to calculate the likelihood of an MS diagnosis among uveitis patients.
Researchers from Casey Eye Institute at the Oregon Health and Science University and the University of Heidelberg in Germany conducted a database search of approximately 3,000 patients with uveitis from the Casey Eye Institute and 5,319 patients from the University of Heidelberg between 1985 and 2013.
Researchers found that MS is 18 times more likely in an American population 21 times and more likely in a European population with uveitis, relative to the general population. The study found that MS was diagnosed before uveitis in 29 percent of patients, simultaneously in 15 percent of patients, and after uveitis diagnosis in 56 percent of patients.
Uveitis causes swelling and irritation of the middle layer of the eye and can lead to permanent vision loss if left untreated. Uveitis can be a sign of MS, and it is estimated that 1 to 10 percent of MS patients have uveitis.
The study was presented at AAO 2014, the 118th annual meeting of the American Academy of Ophthalmology in Chicago.