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Monday, September 19, 2016
Siponimod May Slow Worsening in SPMS
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EXPAND study shows 21% reduction in 3-month confirmed disability progression
September 17, 2016
LONDON -- A novel sphingosine-1-phosphate (S1P) receptor modulator may stall disability progression in patients with secondary progressive MS, researchers reported here.
In the EXPAND study, SPMS patients on siponimod had a 21% reduced risk of 3-month confirmed disability progression compared with those on placebo (HR 0.79, 95% CI 0.65 to 0.95, P=0.013), Ludwig Kappos, MD, of University Hospital Basel in Switzerland, reported during a late-breaking session at the ECTRIMS meeting here.
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