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Sunday, November 13, 2016

Alemtuzumab Better than Interferon in Multiple Sclerosis -


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Alemtuzumab provided more benefits to patients with relapsing remitting multiple sclerosis (RRMS) who had poor response to other therapies than subcutaneous interferon-B-1a (SC IFN-B-1a) provided, according to the results of a recent study. Conducted by Gavin Giovannoni, MD, PhD, of Queen Mary University of London, and colleagues, the study was published in the journal Neurology on October 12, 2016.   

The authors begin by discussing the fact that limiting disability is an important part of caring for patients with MS, but that interest is increasing in not only limiting disability but in helping patients with disability improve. They say, “Interest is growing in aiming for confirmed disability improvement (CDI), a higher standard for therapeutic efficacy than merely slowing disability accumulation.” In pursuit of that goal, the researchers say the aim of the present study was “to characterize effects of alemtuzumab treatment on measures of disability improvement in patients with relapsing remitting multiple sclerosis with inadequate response to prior therapy.” 

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