Please visit our MS learning channel on YouTube, which provides hundreds of MS related topics from many of our video recorded education programs and archived here: -- Be empowered with MS views and news. Opt-in with us:

~~ Scroll left side of this blog for needed resources. Also, use our 'search by topic' tool, to find specific information.

Disclaimer: 'MS Views and News' DOES NOT endorse any products or services found on this blog. It is up to you to seek advice from your healthcare provider. The intent of this blog is to provide information on various medical conditions, medications, treatments, and procedures for your personal knowledge and to keep you informed of current health-related issues. It is not intended to be complete or exhaustive, nor is it a substitute for the advice of your physician. Should you or your family members have any specific medical problem, seek medical care promptly.


Thursday, December 8, 2016

Study Detailing New Way T-cells Attack Myelin May Explain Why Some MS Therapies Fail


Click here to receive MS news via e-mail

In a new and possibly important insight into the workings of the immune system, researchers discovered what it takes for T-cells to start targeting myelin sheets in multiple sclerosis (MS). The findings may also explain why some drugs fail to prevent autoimmunity in MS.
In earlier studies, the research team at Technical University of Munich(TUM) in Germany showed that the immune mediator IL-6 was part of the machinery that instructed T-cells (of a type called Th17) to attack myelin.
When T-cells are formed, they travel to lymph nodes throughout the body and wait for signals to act. Another immune cell — the dendritic cell — is crucial in telling the T-cells where their work is needed. This is done by presenting bits of the invader that the body wants to get rid of.
Most often, these are bits of bacteria or a virus. But in people with MS, dendritic cells wrongfully bring pieces of myelin to the T-cells. The TUM research team discovered that T-cells did not attack the myelin until an IL-6 signal was present.
Read More

MS Views and News
Providing educational information, resources and services for those affected by MS

No comments: