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Tuesday, May 9, 2017

Pregnant Women with Relapsing MS Can Use Copaxone Without Harming Baby, Study Indicates

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Babies of women with relapsing multiple sclerosis (RMS) who receive daily injections of Copaxone (glatiramer acetate) while pregnant carry the same risk of developing birth defects as babies as a whole, according to a study by the therapy’s developer, Teva Pharmaceutical Industries.

The findings can help doctors counsel and treat women with RMS who become pregnant. The study, “Pregnancy Outcomes From The Branded Glatiramer Acetate Pregnancy Database,” was published in the International Journal of MS Care.
Copaxone is a synthetic protein that simulates the production of myelin, a substance that protects nerve fibers in the brain and spinal cord and that is degraded in MS. The drug also suppresses the immune system by preventing T-cells — a type of immune system cells — from damaging myelin in a process called demyelination.
There have been no well-controlled studies in pregnant women’s use of Copaxone until now.
Teva decided to investigate whether babies born to MS patients treated with Copaxone while pregnant were at higher risk of having a congenital problem than babies as a whole.
Researchers compared data on babies born to Copaxone-treated MS patients with data on babies born to healthy women.

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Losing Our Independence Due to Multiple Sclerosis

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Losing our independence due to multiple sclerosis is a profound loss. With that loss comes the grieving process and inevitable change.
On in “A Message from David Kessler,” he discusses the five stages of grief: denial, anger, bargaining, depression and acceptance. I have experienced all of these stages with each new obstacle I encounter. For me, the hardest stages to conquer are denial and acceptance.
Driving was probably the biggest thing that gave me independence and freedom. I was in denial that I had to give it up at first, but then made the decision on my own that it was for the best. Cognitive issues not only make driving unsafe for me, but for others as well.
When my brain gets overstimulated, I get overwhelmed and stressed. Once I get stressed I can’t think clearly, my mind will drift off focus or even go blank. It becomes a chain reaction of events that keep me from driving. I accept that this is where I’m at right now, but it was not an easy decision.

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Statins could soon treat multiple sclerosis as 'momentous' trial begins

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Sarah Knapton, science editor 9 MAY 2017 • 12:01AM

Statins could soon be prescribed to treat multiple sclerosis after a groundbreaking trial began to see if the cheap cholesterol busting drug could delay symptoms.

The £6 million project is being led by University College London and involves 1,180 people at 30 centres across Britain.

It follows a successful small trial in 2014 which showed a significant reduction in the rate of brain shrinkage and an increase in mobility after two years for people on high doses of simvastatin , which usually prescribed to lower cholesterol.

Read complete article by clicking here

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Monday, May 8, 2017

How Patients Cope With The Impact of Multiple Sclerosis

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Apr 14 2017 - 1:37pm
Multiple Sclerosis Life
Living with Multiple Sclerosis means coping with a number of daily challenges. These stories of people living with MS tell that fatigue, pain, brain fog, constipation, hands feeling swollen like balloons, feet on fire, tingling pins and needles are all daily problems to be dealt with.
I would like to share some of these stories from people who live with Multiple Sclerosis with the hope to inspire other people. Yesterday I asked how people with MS cope with the daily life on Multiple Sclerosis Support Facebook group. Here are some of the stories from them.
"The way I handle my fatigue is to take a nap. I try to rest without falling asleep. However, I have yet to master the art," writes Desta from the group. She says she also forces herself to get up. That depends on when she rests. "If I rest in the early afternoon (1, 2, or 3), I am good for the night. If I rest late afternoon (4-5, or 6) I will have trouble sleeping. I also try to get up at 5AM for devotions and meditations. I also try to get in a half hour of stretching. I am usually ready by 7AM. I try to keep a routine so I can sleep at nights," she adds. See how assistive devices can help people with MS.
Living with MS is like having fatigue, joint pains, heat rash, sometimes pins and needles and spasms, writes Jackie. "A lot depends on weather and how tired I am. Try and get a lot of rest. It's easier now as I am retired and exercise."
"My MS story is filled with fatigue, joint pain, insomnia, migraines and even memory loss," writes Krissy. "I just take every day slowly. I try not to overwhelm myself. And I relax as much as possible."
Cope With MS Symptoms by Making a To-Do List
Another group member, named Linda, writes that she rests every day after lunch time. Her memory is short. She uses a to-do list, which she writes on a binder. This helps her to remember the things she needs to do. Living life with Multiple Sclerosis and with a plan works for her and helps to get her life more organized.

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Managing the Emotional Side of Multiple Sclerosis

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Medical approaches and lifestyle changes can help keep anxiety
 and depression in check.

By Heidi Godman, Contributor | April 28, 2017, 

A sad woman sitting on a sofa.

You may think of multiple sclerosis as a physical condition, one that injures nerves and results in symptoms such as weakness, fatigue, trouble walking, bladder problems or vision loss. But MS has a profound, lifelong emotional component that includes mood swings, anxiety and depression. “MS is a chronic condition. Dealing with the emotional part of it requires an evolving approach, just like dealing with the neurological part of it,” says Dr. Christopher Stewart, a neuropsychologist and assistant professor at Rush University Medical Center.
The Emotional Link
In MS, your immune system attacks the coating of the nerves (called myelin) as well as the nerve fibers. Damage can occur along the spinal cord and optic nerves, and in the brain. “Damage in areas of the brain associated with mood – such as the prefrontal cortex and the amygdala – may affect emotional processing,” suggests Dr. Peter Arnett, a professor of psychology at Penn State University who’s been studying emotional function in people with MS for 20 years. He says the interruption of nerve signals causes the neurons to misfire, which may lead to irritability and mood swings.
MS is also commonly associated with anxiety disorders – characterized by obsessive worrying or fear that doesn’t go away – and clinical depression, which can include persistent feelings of hopelessness or sadness that last for more than two weeksTreatment guidelines issued in 2014 by the American Academy of Neurology suggest that over a lifetime, up to 54 percent of people with MS will experience depression at some point. “But a lot of people with MS may not yet be diagnosed. At any given time, more than 20 percent of people with MS may have depression,” Arnett says.
It’s unclear why and when depression develops in people with MS. “It depends on the location of the lesions and the amount of brain atrophy (shrinkage) and disruption of pathways in the brain. That explains about 40 percent of depression in MS,” Arnett explains.

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Here is a video showing (to a degree), what it's like to have MS - SHARE Please


This video, "The Show MUST GO ON" - was filmed by one of our peers in 2007.
 I have been posting this to various sites, on and off since the beginning and now it is time again.

This is a film by Kristie Salerno Kent about living with MS.


 Kristie did an awesome job in helping to describe what many of us feel and yet cannot describe to others. Kristie made this film several years ago, and as said, I have shared it before and want to share it again and again...

Especially now, when Governments needs to be better aware

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