A new assessment of ocrelizumab (Ocrevus) in patients with primary progressive multiple sclerosis (PPMS) has found the monoclonal antibody has capability to reduce patient risk of upper extremity (UE) disability progression.
In new findings from the phase 3 randomized ORATORIO trial, investigators analyzed ocrelizumab versus placebo in an intent-to-treat patient population stratified by Nine-Hole Peg Test (9HPT) and Expanded Disability Status Scale (EDSS) scores at baseline. Assessing for reduced risk of disability progression remains a focal point for progressing MS care.
Led by Edward J. Fox, MD, of Penn State Health, the team emphasized how the rare MS subtype PPMS is characterized by the gradual debilitation of patient neurological ability that could affect their everyday motor, sensory, coordination, and cognitive function.
In new findings from the phase 3 randomized ORATORIO trial, investigators analyzed ocrelizumab versus placebo in an intent-to-treat patient population stratified by Nine-Hole Peg Test (9HPT) and Expanded Disability Status Scale (EDSS) scores at baseline. Assessing for reduced risk of disability progression remains a focal point for progressing MS care.
Led by Edward J. Fox, MD, of Penn State Health, the team emphasized how the rare MS subtype PPMS is characterized by the gradual debilitation of patient neurological ability that could affect their everyday motor, sensory, coordination, and cognitive function.
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