Targeting Gut Immune Cells May Alleviate Brain Inflammation in MS, Study Suggests

A type of immune cell from the gut can reduce brain inflammation in people with multiple sclerosis (MS), and increasing the numbers of these cells in a mouse model of the disease halts inflammation completely, new research reports.

These findings were reported in the study, “Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10,” published in the journal Cell.

In MS, immune cells in the central nervous system attack myelin — the protective sheath around nerve fibers that is critical to an efficient conduction of electrical impulses between the brain and other parts of the body.

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